Zinc in PDB 4ado: Fusidic Acid Resistance Protein Fusb

The structure of Fusidic Acid Resistance Protein Fusb, PDB code: 4ado was solved by X.Guo, K.Peisker, K.Backbro, Y.Chen, R.K.Kiran, S.Sanyal, M.Selmer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.872 / 2.30
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	44.780, 47.310, 53.000, 89.87, 83.41, 85.66
R / Rfree (%)	20.41 / 25.43

The binding sites of Zinc atom in the Fusidic Acid Resistance Protein Fusb (pdb code 4ado). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Fusidic Acid Resistance Protein Fusb, PDB code: 4ado:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Fusidic Acid Resistance Protein Fusb


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Fusidic Acid Resistance Protein Fusb within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1223 b:19.7 occ:1.00 SG A:CYS204 2.3 16.1 1.0 SG A:CYS169 2.3 20.6 1.0 SG A:CYS198 2.4 15.8 1.0 SG A:CYS166 2.4 15.7 1.0 CB A:CYS166 3.0 13.5 1.0 CB A:CYS204 3.2 16.1 1.0 CB A:CYS169 3.3 13.9 1.0 CB A:CYS198 3.3 16.6 1.0 CA A:CYS204 3.6 28.4 1.0 N A:CYS169 3.7 18.5 1.0 N A:CYS198 3.9 19.2 1.0 CA A:CYS169 4.1 20.8 1.0 CA A:CYS198 4.2 20.2 1.0 CA A:CYS166 4.5 18.9 1.0 C A:CYS204 4.5 28.9 1.0 O A:CYS204 4.5 23.7 1.0 CB A:ILE168 4.5 21.0 1.0 OE1 A:GLN207 4.7 45.7 1.0 N A:CYS204 4.8 19.0 1.0 OG A:SER173 4.8 29.8 1.0 C A:ILE168 4.8 30.1 1.0 C A:CYS169 4.9 22.3 1.0 CG2 A:ILE168 4.9 22.2 1.0 O A:HOH2047 5.0 22.9 1.0

Zinc binding site 2 out of 2 in the Fusidic Acid Resistance Protein Fusb


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Fusidic Acid Resistance Protein Fusb within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1222 b:24.5 occ:1.00 SG B:CYS169 2.3 22.9 1.0 SG B:CYS204 2.3 16.1 1.0 SG B:CYS198 2.4 26.6 1.0 SG B:CYS166 2.4 22.1 1.0 CB B:CYS166 3.1 23.4 1.0 CB B:CYS169 3.2 20.7 1.0 CB B:CYS204 3.3 23.2 1.0 CB B:CYS198 3.3 15.9 1.0 CA B:CYS204 3.6 26.9 1.0 N B:CYS169 3.7 11.7 1.0 N B:CYS198 3.9 21.1 1.0 CA B:CYS169 4.0 21.7 1.0 CA B:CYS198 4.2 19.0 1.0 O B:CYS204 4.4 24.6 1.0 C B:CYS204 4.4 31.1 1.0 OE1 B:GLN207 4.5 42.3 1.0 CB B:ILE168 4.6 26.1 1.0 CA B:CYS166 4.6 22.8 1.0 O B:HOH2044 4.7 27.4 1.0 N B:CYS204 4.8 25.4 1.0 C B:ILE168 4.8 26.0 1.0 OG B:SER173 4.9 33.4 1.0 C B:CYS169 5.0 24.6 1.0

X.Guo, K.Peisker, K.Backbro, Y.Chen, R.K.Kiran, C.S.Mandava, S.Sanyal, M.Selmer. Structure and Function of Fusb: An Elongation Factor G-Binding Fusidic Acid Resistance Protein Active in Ribosomal Translocation and Recycling Open Biol. V. 2 20016 2012.
ISSN: ISSN 2046-2441
PubMed: 22645663
DOI: 10.1098/RSOB.120016