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Atomistry » Zinc » PDB 3vh2-3w51 » 3w51 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 3vh2-3w51 » 3w51 » |
Zinc in PDB 3w51: Tankyrase in Complex with 2-Hydroxy-4-MethylquinolineEnzymatic activity of Tankyrase in Complex with 2-Hydroxy-4-Methylquinoline
All present enzymatic activity of Tankyrase in Complex with 2-Hydroxy-4-Methylquinoline:
2.4.2.30; Protein crystallography data
The structure of Tankyrase in Complex with 2-Hydroxy-4-Methylquinoline, PDB code: 3w51
was solved by
A.E.Jansson,
E.A.Larsson,
P.L.Nordlund,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Tankyrase in Complex with 2-Hydroxy-4-Methylquinoline
(pdb code 3w51). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Tankyrase in Complex with 2-Hydroxy-4-Methylquinoline, PDB code: 3w51: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 3w51Go back to Zinc Binding Sites List in 3w51
Zinc binding site 1 out
of 2 in the Tankyrase in Complex with 2-Hydroxy-4-Methylquinoline
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 3w51Go back to Zinc Binding Sites List in 3w51
Zinc binding site 2 out
of 2 in the Tankyrase in Complex with 2-Hydroxy-4-Methylquinoline
Mono view Stereo pair view
Reference:
E.A.Larsson,
A.E.Jansson,
F.M.Ng,
S.W.Then,
R.Panicker,
B.Liu,
K.Sangthongpitag,
V.Pendharkar,
S.J.Tai,
J.Hill,
C.Dan,
S.Y.Ho,
W.W.Cheong,
A.Poulsen,
S.Blanchard,
G.R.Lin,
J.Alam,
T.H.Keller,
P.Nordlund.
Fragment-Based Ligand Design of Novel Potent Inhibitors of Tankyrases. J.Med.Chem. V. 56 4497 2013.
Page generated: Sat Oct 26 17:57:30 2024
ISSN: ISSN 0022-2623 PubMed: 23672613 DOI: 10.1021/JM400211F |
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