Zinc in PDB 3v19: Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health

The structure of Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health, PDB code: 3v19 was solved by Z.L.Wan, Q.X.Hua, N.P.Wickramasinghe, K.Huang, A.T.Petkova, S.Q.Hu, N.B.Phillips, I.J.Yeh, J.Whittake, F.Ismail-Beigi, P.G.Katsoyyannis, R.Tycko, M.A.Weiss, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	16.69 / 2.00
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	78.301, 78.301, 36.224, 90.00, 90.00, 120.00
R / Rfree (%)	20.8 / 26.6

The structure of Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health also contains other interesting chemical elements:

Chlorine

(Cl)

2 atoms

The binding sites of Zinc atom in the Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health (pdb code 3v19). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health, PDB code: 3v19:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn101 b:7.5 occ:0.33 NE2 B:HIS10 2.1 34.5 1.0 CL B:CL102 2.3 43.7 0.3 CE1 B:HIS10 3.1 37.6 1.0 CD2 B:HIS10 3.1 32.6 1.0 ND1 B:HIS10 4.2 36.8 1.0 CG B:HIS10 4.2 35.2 1.0 O B:HOH31 4.9 57.6 0.3

Zinc binding site 2 out of 2 in the Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn201 b:1.3 occ:0.33 NE2 D:HIS10 2.1 28.6 1.0 CL D:CL202 2.3 2.1 0.3 CE1 D:HIS10 3.0 32.9 1.0 CD2 D:HIS10 3.1 26.2 1.0 ND1 D:HIS10 4.2 28.3 1.0 CG D:HIS10 4.2 25.8 1.0 O D:LEU6 4.7 25.2 1.0 CB D:LEU6 4.7 26.4 1.0

Z.L.Wan, Q.X.Hua, N.P.Wickramasinghe, K.Huang, A.T.Petkova, S.Q.Hu, N.B.Phillips, I.J.Yeh, J.Whittake, F.Ismail-Beigi, P.G.Katsoyyannis, R.Tycko, M.A.Weiss. Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health To Be Published.