Zinc in PDB 3uwx: Crystal Structure of Uvra-Uvrb Complex

The structure of Crystal Structure of Uvra-Uvrb Complex, PDB code: 3uwx was solved by D.Pakotiprapha, D.Jeruzalmi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.06 / 4.40
Space group	P 42 21 2
Cell size a, b, c (Å), α, β, γ (°)	216.823, 216.823, 116.802, 90.00, 90.00, 90.00
R / Rfree (%)	28.8 / 34.9

The binding sites of Zinc atom in the Crystal Structure of Uvra-Uvrb Complex (pdb code 3uwx). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Crystal Structure of Uvra-Uvrb Complex, PDB code: 3uwx:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Crystal Structure of Uvra-Uvrb Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Uvra-Uvrb Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1004 b:0.0 occ:1.01 ND1 A:HIS123 2.0 0.8 1.0 SG A:CYS250 2.2 0.7 1.0 SG A:CYS120 2.3 0.3 1.0 CB A:HIS123 2.4 0.4 1.0 CG A:HIS123 2.5 0.1 1.0 CB A:CYS120 2.9 0.4 1.0 CE1 A:HIS123 3.3 0.4 1.0 N A:HIS123 3.5 0.5 1.0 CA A:HIS123 3.5 0.5 1.0 CB A:CYS250 3.6 0.2 1.0 SG A:CYS253 3.6 0.2 1.0 CD2 A:HIS123 3.8 0.4 1.0 CG2 A:ILE125 4.1 0.1 1.0 NE2 A:HIS123 4.1 0.9 1.0 C A:HIS123 4.4 0.5 1.0 CA A:CYS120 4.4 0.5 1.0 CD2 A:TYR252 4.5 0.1 1.0 C A:THR122 4.6 0.6 1.0 CB A:TYR252 4.7 0.9 1.0 N A:GLY124 4.7 0.5 1.0 CB A:CYS253 4.7 0.6 1.0 CB A:THR122 4.8 0.1 1.0 C A:CYS120 4.9 0.4 1.0 CA A:CYS250 4.9 0.3 1.0 N A:CYS253 5.0 0.3 1.0

Zinc binding site 2 out of 3 in the Crystal Structure of Uvra-Uvrb Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Uvra-Uvrb Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1005 b:0.0 occ:1.01 SG A:CYS277 2.2 0.5 1.0 SG A:CYS407 2.2 0.3 1.0 SG A:CYS404 2.4 0.2 1.0 CB A:CYS404 2.8 0.1 1.0 CB A:CYS277 3.1 0.3 1.0 SG A:CYS274 3.2 0.1 1.0 CB A:CYS407 3.4 0.4 1.0 CB A:CYS274 3.5 0.6 1.0 CA A:GLY281 4.0 0.7 1.0 N A:GLY281 4.0 0.7 1.0 CA A:CYS404 4.3 0.7 1.0 CA A:CYS277 4.3 0.2 1.0 CA A:ARG411 4.3 0.5 1.0 N A:CYS407 4.4 0.2 1.0 N A:CYS277 4.5 0.8 1.0 CA A:CYS407 4.5 0.2 1.0 N A:ARG411 4.5 0.6 1.0 C A:GLY281 4.7 0.9 1.0 C A:CYS404 4.9 0.6 1.0 O A:CYS404 4.9 0.4 1.0 C A:ARG411 4.9 0.9 1.0 CA A:CYS274 5.0 0.9 1.0 C A:CYS277 5.0 0.9 1.0

Zinc binding site 3 out of 3 in the Crystal Structure of Uvra-Uvrb Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of Uvra-Uvrb Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1006 b:0.0 occ:1.01 SG A:CYS739 2.2 0.4 1.0 CB A:CYS739 2.3 0.1 1.0 SG A:CYS736 2.3 0.7 1.0 N A:CYS739 2.4 0.6 1.0 SG A:CYS759 2.4 0.8 1.0 CA A:CYS739 2.8 0.5 1.0 CB A:CYS736 3.1 1.0 1.0 SG A:CYS762 3.4 0.3 1.0 CB A:CYS759 3.4 0.6 1.0 C A:ALA738 3.5 0.2 1.0 CB A:ALA738 3.7 0.3 1.0 O A:CYS736 3.8 1.0 1.0 C A:CYS739 3.9 0.8 1.0 CA A:ALA738 4.0 0.7 1.0 N A:ALA738 4.1 0.8 1.0 C A:CYS736 4.2 0.9 1.0 CA A:CYS736 4.2 0.1 1.0 N A:HIS740 4.3 0.7 1.0 CB A:CYS762 4.3 0.5 1.0 O A:ALA738 4.6 0.2 1.0 N A:CYS762 4.7 0.1 1.0 N A:GLY743 4.8 0.6 1.0 O A:CYS739 4.8 0.9 1.0 CA A:GLY743 4.9 0.1 1.0 CA A:CYS759 4.9 0.2 1.0 CB A:VAL761 4.9 0.3 1.0

D.Pakotiprapha, M.Samuels, K.Shen, J.H.Hu, D.Jeruzalmi. Structure and Mechanism of the Uvra-Uvrb Dna Damage Sensor. Nat.Struct.Mol.Biol. V. 19 291 2012.
ISSN: ISSN 1545-9993
PubMed: 22307053
DOI: 10.1038/NSMB.2240