|
Atomistry » Zinc » PDB 3tts-3u6m » 3tyn | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 3tts-3u6m » 3tyn » |
Zinc in PDB 3tyn: Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 2-(((2-(((3S,4S)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Ethyl)Amino)Methyl)PhenolEnzymatic activity of Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 2-(((2-(((3S,4S)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Ethyl)Amino)Methyl)Phenol
All present enzymatic activity of Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 2-(((2-(((3S,4S)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Ethyl)Amino)Methyl)Phenol:
1.14.13.39; Protein crystallography data
The structure of Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 2-(((2-(((3S,4S)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Ethyl)Amino)Methyl)Phenol, PDB code: 3tyn
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3tyn:
The structure of Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 2-(((2-(((3S,4S)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Ethyl)Amino)Methyl)Phenol also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 2-(((2-(((3S,4S)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Ethyl)Amino)Methyl)Phenol
(pdb code 3tyn). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 2-(((2-(((3S,4S)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Ethyl)Amino)Methyl)Phenol, PDB code: 3tyn: Zinc binding site 1 out of 1 in 3tynGo back to Zinc Binding Sites List in 3tyn
Zinc binding site 1 out
of 1 in the Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 2-(((2-(((3S,4S)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Ethyl)Amino)Methyl)Phenol
Mono view Stereo pair view
Reference:
K.J.Labby,
F.Xue,
J.M.Kraus,
H.Ji,
J.Mataka,
H.Li,
P.Martasek,
L.J.Roman,
T.L.Poulos,
R.B.Silverman.
Intramolecular Hydrogen Bonding: A Potential Strategy For More Bioavailable Inhibitors of Neuronal Nitric Oxide Synthase. Bioorg.Med.Chem. V. 20 2435 2012.
Page generated: Sat Oct 26 16:49:57 2024
ISSN: ISSN 0968-0896 PubMed: 22370337 DOI: 10.1016/J.BMC.2012.01.037 |
Last articlesZn in 9JYWZn in 9IR4 Zn in 9IR3 Zn in 9GMX Zn in 9GMW Zn in 9JEJ Zn in 9ERF Zn in 9ERE Zn in 9EGV Zn in 9EGW |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |