Zinc in PDB 3mwm: Graded Expression of Zinc-Responsive Genes Through Two Regulatory Zinc-Binding Sites in Zur

The structure of Graded Expression of Zinc-Responsive Genes Through Two Regulatory Zinc-Binding Sites in Zur, PDB code: 3mwm was solved by H.J.Jung, Y.J.An, S.-S.Cha, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	26.02 / 2.40
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	103.599, 36.978, 71.645, 90.00, 103.26, 90.00
R / Rfree (%)	20.6 / 24.6

The binding sites of Zinc atom in the Graded Expression of Zinc-Responsive Genes Through Two Regulatory Zinc-Binding Sites in Zur (pdb code 3mwm). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 6 binding sites of Zinc where determined in the Graded Expression of Zinc-Responsive Genes Through Two Regulatory Zinc-Binding Sites in Zur, PDB code: 3mwm:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6;

Zinc binding site 1 out of 6 in the Graded Expression of Zinc-Responsive Genes Through Two Regulatory Zinc-Binding Sites in Zur


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Graded Expression of Zinc-Responsive Genes Through Two Regulatory Zinc-Binding Sites in Zur within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn140 b:41.3 occ:1.00 SG A:CYS93 2.3 17.3 1.0 SG A:CYS130 2.3 18.8 1.0 SG A:CYS133 2.3 22.9 1.0 SG A:CYS90 2.3 17.2 1.0 CB A:CYS93 3.1 14.4 1.0 CB A:CYS90 3.3 15.4 1.0 CB A:CYS133 3.4 26.1 1.0 N A:CYS93 3.5 17.8 1.0 CB A:CYS130 3.6 16.1 1.0 CA A:CYS93 3.9 16.6 1.0 N A:CYS133 4.2 27.0 1.0 N A:CYS130 4.2 12.9 1.0 CB A:ALA92 4.3 17.6 1.0 CA A:CYS133 4.4 26.6 1.0 CA A:CYS130 4.4 15.5 1.0 C A:ALA92 4.5 19.3 1.0 CB A:LYS95 4.6 12.5 1.0 CE A:LYS95 4.7 17.1 1.0 NZ A:LYS95 4.7 21.0 1.0 CA A:CYS90 4.7 17.1 1.0 O A:CYS130 4.7 17.9 1.0 C A:CYS93 4.7 15.4 1.0 N A:GLY94 4.8 15.1 1.0 CA A:ALA92 4.8 19.7 1.0 C A:CYS130 4.9 17.4 1.0 N A:ALA92 5.0 19.2 1.0 N A:LYS95 5.0 11.9 1.0

Zinc binding site 2 out of 6 in the Graded Expression of Zinc-Responsive Genes Through Two Regulatory Zinc-Binding Sites in Zur


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Graded Expression of Zinc-Responsive Genes Through Two Regulatory Zinc-Binding Sites in Zur within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn141 b:35.1 occ:1.00 OD2 A:ASP65 1.9 21.0 1.0 NE2 A:HIS87 2.0 3.6 1.0 NE2 A:HIS85 2.0 8.8 1.0 SG A:CYS79 2.2 24.0 1.0 CD2 A:HIS87 2.8 3.8 1.0 CD2 A:HIS85 2.9 8.0 1.0 CG A:ASP65 2.9 20.1 1.0 CE1 A:HIS85 3.0 7.2 1.0 CE1 A:HIS87 3.0 2.6 1.0 CB A:CYS79 3.2 21.3 1.0 CB A:ASP65 3.4 17.0 1.0 OD1 A:ASP65 4.0 21.1 1.0 CG A:HIS87 4.0 3.7 1.0 ND1 A:HIS85 4.0 9.2 1.0 CG A:HIS85 4.0 8.3 1.0 ND1 A:HIS87 4.1 3.4 1.0 CG A:GLU98 4.4 15.3 1.0 CA A:CYS79 4.6 21.2 1.0 CA A:ASP65 4.9 17.2 1.0 OE2 A:GLU98 4.9 18.6 1.0 CD A:GLU98 5.0 17.9 1.0 NE A:ARG77 5.0 16.1 1.0

Zinc binding site 3 out of 6 in the Graded Expression of Zinc-Responsive Genes Through Two Regulatory Zinc-Binding Sites in Zur


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Graded Expression of Zinc-Responsive Genes Through Two Regulatory Zinc-Binding Sites in Zur within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn142 b:41.7 occ:1.00 OE2 A:GLU105 1.6 24.7 1.0 NE2 A:HIS84 2.0 16.3 1.0 NE2 A:HIS122 2.0 14.2 1.0 NE2 A:HIS86 2.0 12.4 1.0 CD A:GLU105 2.7 24.2 1.0 CD2 A:HIS84 2.9 15.9 1.0 CE1 A:HIS122 2.9 17.5 1.0 CE1 A:HIS86 2.9 11.1 1.0 CE1 A:HIS84 3.0 16.2 1.0 CD2 A:HIS86 3.1 8.6 1.0 CD2 A:HIS122 3.1 16.3 1.0 OE1 A:GLU105 3.2 27.2 1.0 CG A:GLU105 3.9 24.1 1.0 CG A:HIS84 4.0 15.5 1.0 ND1 A:HIS84 4.0 15.6 1.0 ND1 A:HIS122 4.1 16.6 1.0 ND1 A:HIS86 4.1 12.8 1.0 CG A:HIS86 4.2 10.1 1.0 CG A:HIS122 4.2 15.8 1.0 O A:HOH174 4.6 31.8 1.0 O A:HOH161 4.8 17.0 1.0

Zinc binding site 4 out of 6 in the Graded Expression of Zinc-Responsive Genes Through Two Regulatory Zinc-Binding Sites in Zur


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Graded Expression of Zinc-Responsive Genes Through Two Regulatory Zinc-Binding Sites in Zur within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn140 b:36.0 occ:1.00 NE2 B:HIS87 1.8 8.2 1.0 NE2 B:HIS85 2.0 15.2 1.0 OD2 B:ASP65 2.1 15.2 1.0 SG B:CYS79 2.2 18.4 1.0 CD2 B:HIS87 2.7 11.1 1.0 CE1 B:HIS87 2.9 8.8 1.0 CD2 B:HIS85 2.9 13.7 1.0 CE1 B:HIS85 3.0 14.3 1.0 CG B:ASP65 3.1 15.2 1.0 CB B:CYS79 3.2 19.3 1.0 CB B:ASP65 3.6 12.9 1.0 CG B:HIS87 3.8 10.2 1.0 ND1 B:HIS87 3.9 10.0 1.0 CG B:HIS85 4.0 14.0 1.0 ND1 B:HIS85 4.1 13.4 1.0 OD1 B:ASP65 4.2 14.8 1.0 CG B:GLU98 4.4 14.9 1.0 CA B:CYS79 4.6 20.0 1.0 NH2 B:ARG77 4.9 21.9 1.0 CZ B:PHE29 5.0 6.7 1.0

Zinc binding site 5 out of 6 in the Graded Expression of Zinc-Responsive Genes Through Two Regulatory Zinc-Binding Sites in Zur


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Graded Expression of Zinc-Responsive Genes Through Two Regulatory Zinc-Binding Sites in Zur within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn141 b:52.2 occ:1.00 SG B:CYS133 2.2 33.8 1.0 SG B:CYS93 2.3 19.8 1.0 SG B:CYS130 2.4 23.5 1.0 SG B:CYS90 2.6 10.1 1.0 CB B:CYS93 3.2 17.1 1.0 CB B:CYS90 3.3 11.2 1.0 CB B:CYS133 3.4 34.5 1.0 N B:CYS93 3.7 18.6 1.0 CB B:CYS130 3.8 20.6 1.0 CA B:CYS93 4.0 17.4 1.0 N B:CYS130 4.3 16.7 1.0 CB B:LYS95 4.4 16.7 1.0 N B:CYS133 4.5 33.8 1.0 CB B:ALA92 4.5 19.8 1.0 CA B:CYS133 4.5 35.0 1.0 C B:ALA92 4.6 20.1 1.0 CA B:CYS130 4.6 19.6 1.0 C B:CYS93 4.8 16.6 1.0 CA B:CYS90 4.8 12.0 1.0 N B:LYS95 4.9 15.1 1.0 CA B:ALA92 4.9 20.6 1.0 N B:GLY94 5.0 16.0 1.0

Zinc binding site 6 out of 6 in the Graded Expression of Zinc-Responsive Genes Through Two Regulatory Zinc-Binding Sites in Zur


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Graded Expression of Zinc-Responsive Genes Through Two Regulatory Zinc-Binding Sites in Zur within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn142 b:40.0 occ:1.00 NE2 B:HIS84 1.8 12.4 1.0 OE1 B:GLU105 1.8 9.4 1.0 NE2 B:HIS86 2.1 10.5 1.0 NE2 B:HIS122 2.1 18.6 1.0 CD B:GLU105 2.5 13.9 1.0 OE2 B:GLU105 2.7 11.9 1.0 CD2 B:HIS84 2.8 11.4 1.0 CE1 B:HIS84 2.8 8.2 1.0 CE1 B:HIS122 3.0 19.6 1.0 CE1 B:HIS86 3.0 9.5 1.0 CD2 B:HIS86 3.2 8.1 1.0 CD2 B:HIS122 3.2 19.2 1.0 ND1 B:HIS84 3.9 10.5 1.0 CG B:HIS84 3.9 11.7 1.0 CG B:GLU105 4.0 14.4 1.0 ND1 B:HIS122 4.2 19.3 1.0 ND1 B:HIS86 4.2 11.1 1.0 CG B:HIS86 4.3 10.3 1.0 CG B:HIS122 4.3 18.1 1.0

J.-H.Shin, H.J.Jung, Y.J.An, Y.-B.Cho, S.-S.Cha, J.-H.Roe. Graded Expression of Zinc-Responsive Genes Through Two Regulatory Zinc-Binding Sites in Zur Proc.Natl.Acad.Sci.Usa V. 108 5045 2011.
ISSN: ISSN 0027-8424
PubMed: 21383173
DOI: 10.1073/PNAS.1017744108