Zinc in PDB 3kqz: Structure of A Protease 2
Enzymatic activity of Structure of A Protease 2
All present enzymatic activity of Structure of A Protease 2:
3.4.11.1;
Protein crystallography data
The structure of Structure of A Protease 2, PDB code: 3kqz
was solved by
S.Mcgowan,
J.C.Whisstock,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
56.08 /
2.39
|
|
Space group
|
P 21 21 21
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
171.698,
173.728,
220.278,
90.00,
90.00,
90.00
|
|
R / Rfree (%)
|
17.6 /
24.2
|
Zinc Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
20;
Page 3, Binding sites: 21 -
24;
Binding sites:
The binding sites of Zinc atom in the Structure of A Protease 2
(pdb code 3kqz). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 24 binding sites of Zinc where determined in the
Structure of A Protease 2, PDB code: 3kqz:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Zinc binding site 1 out
of 24 in 3kqz
Go back to
Zinc Binding Sites List in 3kqz
Zinc binding site 1 out
of 24 in the Structure of A Protease 2
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Structure of A Protease 2 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn1004
b:27.2
occ:1.00
|
OD2
|
A:ASP379
|
1.9
|
25.3
|
1.0
|
|
OE1
|
A:GLU461
|
2.0
|
19.5
|
1.0
|
|
OD1
|
A:ASP459
|
2.1
|
23.4
|
1.0
|
|
O
|
A:ASP459
|
2.2
|
23.5
|
1.0
|
|
ZN
|
A:ZN1001
|
2.9
|
29.9
|
1.0
|
|
CG
|
A:ASP379
|
2.9
|
27.6
|
1.0
|
|
CD
|
A:GLU461
|
2.9
|
25.2
|
1.0
|
|
C
|
A:ASP459
|
3.2
|
23.9
|
1.0
|
|
OE2
|
A:GLU461
|
3.2
|
29.2
|
1.0
|
|
CG
|
A:ASP459
|
3.2
|
23.1
|
1.0
|
|
OD1
|
A:ASP379
|
3.2
|
33.2
|
1.0
|
|
CA
|
A:ASP459
|
3.6
|
22.9
|
1.0
|
|
NZ
|
A:LYS386
|
3.9
|
19.8
|
1.0
|
|
CB
|
A:ASP459
|
4.0
|
20.7
|
1.0
|
|
OD2
|
A:ASP459
|
4.1
|
27.5
|
1.0
|
|
OD2
|
A:ASP399
|
4.2
|
19.1
|
1.0
|
|
N
|
A:GLU461
|
4.2
|
22.4
|
1.0
|
|
CB
|
A:ASP379
|
4.2
|
19.6
|
1.0
|
|
O2
|
A:CO31002
|
4.3
|
30.5
|
1.0
|
|
CE
|
A:LYS386
|
4.3
|
28.6
|
1.0
|
|
N
|
A:ALA460
|
4.3
|
24.4
|
1.0
|
|
CG
|
A:GLU461
|
4.3
|
22.4
|
1.0
|
|
NZ
|
A:LYS374
|
4.6
|
16.1
|
1.0
|
|
ND2
|
A:ASN432
|
4.6
|
24.5
|
1.0
|
|
CA
|
A:ALA460
|
4.7
|
23.9
|
1.0
|
|
CA
|
A:GLY381
|
4.8
|
23.8
|
1.0
|
|
CB
|
A:GLU461
|
4.9
|
23.1
|
1.0
|
|
C
|
A:ALA460
|
5.0
|
24.6
|
1.0
|
|
N
|
A:ASP459
|
5.0
|
22.9
|
1.0
|
|
Zinc binding site 2 out
of 24 in 3kqz
Go back to
Zinc Binding Sites List in 3kqz
Zinc binding site 2 out
of 24 in the Structure of A Protease 2
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Structure of A Protease 2 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn1001
b:29.9
occ:1.00
|
OD2
|
A:ASP399
|
1.9
|
19.1
|
1.0
|
|
NZ
|
A:LYS374
|
2.0
|
16.1
|
1.0
|
|
OE2
|
A:GLU461
|
2.1
|
29.2
|
1.0
|
|
OD2
|
A:ASP379
|
2.6
|
25.3
|
1.0
|
|
CG
|
A:ASP399
|
2.8
|
26.2
|
1.0
|
|
CE
|
A:LYS374
|
2.8
|
28.5
|
1.0
|
|
ZN
|
A:ZN1004
|
2.9
|
27.2
|
1.0
|
|
CD
|
A:GLU461
|
3.0
|
25.2
|
1.0
|
|
OD1
|
A:ASP399
|
3.1
|
23.9
|
1.0
|
|
OE1
|
A:GLU461
|
3.2
|
19.5
|
1.0
|
|
CG
|
A:ASP379
|
3.4
|
27.6
|
1.0
|
|
O2
|
A:CO31002
|
3.8
|
30.5
|
1.0
|
|
CB
|
A:ASP379
|
4.0
|
19.6
|
1.0
|
|
CB
|
A:ASP399
|
4.2
|
19.7
|
1.0
|
|
O
|
A:THR486
|
4.2
|
29.2
|
1.0
|
|
CD
|
A:LYS374
|
4.3
|
23.6
|
1.0
|
|
OD1
|
A:ASP379
|
4.3
|
33.2
|
1.0
|
|
N
|
A:GLY462
|
4.4
|
22.2
|
1.0
|
|
CG
|
A:GLU461
|
4.4
|
22.4
|
1.0
|
|
CG1
|
A:ILE376
|
4.5
|
22.3
|
1.0
|
|
O
|
A:ASP459
|
4.6
|
23.5
|
1.0
|
|
CB
|
A:ILE376
|
4.7
|
20.2
|
1.0
|
|
CG2
|
A:ILE376
|
4.7
|
16.8
|
1.0
|
|
CA
|
A:GLY462
|
4.7
|
22.4
|
1.0
|
|
OD1
|
A:ASP459
|
4.8
|
23.4
|
1.0
|
|
OH3
|
A:1PE24
|
5.0
|
41.3
|
1.0
|
|
Zinc binding site 3 out
of 24 in 3kqz
Go back to
Zinc Binding Sites List in 3kqz
Zinc binding site 3 out
of 24 in the Structure of A Protease 2
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Structure of A Protease 2 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn1004
b:26.0
occ:1.00
|
OD2
|
B:ASP379
|
2.0
|
23.2
|
1.0
|
|
OD1
|
B:ASP459
|
2.0
|
29.3
|
1.0
|
|
O
|
B:ASP459
|
2.0
|
28.7
|
1.0
|
|
OE1
|
B:GLU461
|
2.1
|
19.2
|
1.0
|
|
CG
|
B:ASP379
|
2.9
|
20.7
|
1.0
|
|
ZN
|
B:ZN1001
|
2.9
|
27.3
|
1.0
|
|
CD
|
B:GLU461
|
2.9
|
23.9
|
1.0
|
|
C
|
B:ASP459
|
3.0
|
26.9
|
1.0
|
|
CG
|
B:ASP459
|
3.0
|
25.4
|
1.0
|
|
OD1
|
B:ASP379
|
3.1
|
19.1
|
1.0
|
|
OE2
|
B:GLU461
|
3.1
|
26.3
|
1.0
|
|
CA
|
B:ASP459
|
3.4
|
25.9
|
1.0
|
|
CB
|
B:ASP459
|
3.8
|
23.2
|
1.0
|
|
OD2
|
B:ASP459
|
3.9
|
26.1
|
1.0
|
|
NZ
|
B:LYS386
|
4.0
|
23.4
|
1.0
|
|
N
|
B:ALA460
|
4.1
|
25.6
|
1.0
|
|
N
|
B:GLU461
|
4.2
|
23.7
|
1.0
|
|
O2
|
B:CO31002
|
4.3
|
25.1
|
1.0
|
|
CE
|
B:LYS386
|
4.3
|
25.5
|
1.0
|
|
OD2
|
B:ASP399
|
4.3
|
25.8
|
1.0
|
|
CB
|
B:ASP379
|
4.3
|
20.6
|
1.0
|
|
CG
|
B:GLU461
|
4.4
|
20.7
|
1.0
|
|
ND2
|
B:ASN432
|
4.4
|
19.3
|
1.0
|
|
O
|
B:HOH2850
|
4.4
|
41.0
|
1.0
|
|
CA
|
B:ALA460
|
4.6
|
24.7
|
1.0
|
|
NZ
|
B:LYS374
|
4.6
|
25.9
|
1.0
|
|
N
|
B:ASP459
|
4.8
|
25.6
|
1.0
|
|
CB
|
B:GLU461
|
4.8
|
21.3
|
1.0
|
|
O
|
B:THR458
|
4.8
|
26.4
|
1.0
|
|
CA
|
B:GLY381
|
4.8
|
21.1
|
1.0
|
|
C
|
B:ALA460
|
4.9
|
24.0
|
1.0
|
|
C
|
B:CO31002
|
5.0
|
26.9
|
1.0
|
|
Zinc binding site 4 out
of 24 in 3kqz
Go back to
Zinc Binding Sites List in 3kqz
Zinc binding site 4 out
of 24 in the Structure of A Protease 2
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Structure of A Protease 2 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn1001
b:27.3
occ:1.00
|
OD2
|
B:ASP399
|
1.9
|
25.8
|
1.0
|
|
OE2
|
B:GLU461
|
1.9
|
26.3
|
1.0
|
|
NZ
|
B:LYS374
|
2.1
|
25.9
|
1.0
|
|
OD2
|
B:ASP379
|
2.4
|
23.2
|
1.0
|
|
CG
|
B:ASP399
|
2.8
|
25.9
|
1.0
|
|
ZN
|
B:ZN1004
|
2.9
|
26.0
|
1.0
|
|
CE
|
B:LYS374
|
2.9
|
19.1
|
1.0
|
|
CD
|
B:GLU461
|
2.9
|
23.9
|
1.0
|
|
OD1
|
B:ASP399
|
3.1
|
23.0
|
1.0
|
|
OE1
|
B:GLU461
|
3.3
|
19.2
|
1.0
|
|
CG
|
B:ASP379
|
3.4
|
20.7
|
1.0
|
|
O2
|
B:CO31002
|
3.6
|
25.1
|
1.0
|
|
CB
|
B:ASP379
|
4.0
|
20.6
|
1.0
|
|
CB
|
B:ASP399
|
4.2
|
21.1
|
1.0
|
|
O
|
B:THR486
|
4.2
|
28.6
|
1.0
|
|
OD1
|
B:ASP379
|
4.2
|
19.1
|
1.0
|
|
CG
|
B:GLU461
|
4.3
|
20.7
|
1.0
|
|
OH3
|
B:1PE40
|
4.3
|
36.2
|
1.0
|
|
CD
|
B:LYS374
|
4.3
|
26.5
|
1.0
|
|
O
|
B:ASP459
|
4.4
|
28.7
|
1.0
|
|
CG1
|
B:ILE376
|
4.4
|
20.3
|
1.0
|
|
N
|
B:GLY462
|
4.4
|
25.9
|
1.0
|
|
OD1
|
B:ASP459
|
4.7
|
29.3
|
1.0
|
|
CB
|
B:ILE376
|
4.7
|
23.5
|
1.0
|
|
CA
|
B:GLY462
|
4.7
|
26.8
|
1.0
|
|
C
|
B:CO31002
|
4.8
|
26.9
|
1.0
|
|
CG2
|
B:ILE376
|
4.8
|
19.6
|
1.0
|
|
Zinc binding site 5 out
of 24 in 3kqz
Go back to
Zinc Binding Sites List in 3kqz
Zinc binding site 5 out
of 24 in the Structure of A Protease 2
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Structure of A Protease 2 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn1001
b:23.9
occ:1.00
|
OE2
|
C:GLU461
|
1.9
|
17.4
|
1.0
|
|
OD2
|
C:ASP399
|
1.9
|
28.9
|
1.0
|
|
NZ
|
C:LYS374
|
2.1
|
24.4
|
1.0
|
|
OD2
|
C:ASP379
|
2.5
|
24.6
|
1.0
|
|
CG
|
C:ASP399
|
2.8
|
24.5
|
1.0
|
|
ZN
|
C:ZN1004
|
2.8
|
25.7
|
1.0
|
|
CD
|
C:GLU461
|
2.9
|
22.2
|
1.0
|
|
CE
|
C:LYS374
|
2.9
|
19.4
|
1.0
|
|
OD1
|
C:ASP399
|
3.1
|
28.8
|
1.0
|
|
CG
|
C:ASP379
|
3.3
|
24.4
|
1.0
|
|
OE1
|
C:GLU461
|
3.3
|
21.1
|
1.0
|
|
O1
|
C:CO31002
|
3.5
|
27.4
|
1.0
|
|
CB
|
C:ASP379
|
4.0
|
22.4
|
1.0
|
|
OD1
|
C:ASP379
|
4.2
|
23.9
|
1.0
|
|
O
|
C:THR486
|
4.2
|
20.1
|
1.0
|
|
CB
|
C:ASP399
|
4.3
|
20.9
|
1.0
|
|
CG
|
C:GLU461
|
4.3
|
21.1
|
1.0
|
|
CG1
|
C:ILE376
|
4.3
|
20.5
|
1.0
|
|
C13
|
C:1PE41
|
4.3
|
23.2
|
1.0
|
|
CD
|
C:LYS374
|
4.4
|
26.6
|
1.0
|
|
N
|
C:GLY462
|
4.5
|
22.6
|
1.0
|
|
OD1
|
C:ASP459
|
4.6
|
31.6
|
1.0
|
|
CB
|
C:ILE376
|
4.6
|
22.5
|
1.0
|
|
CG2
|
C:ILE376
|
4.7
|
21.6
|
1.0
|
|
CA
|
C:GLY462
|
4.7
|
22.5
|
1.0
|
|
O
|
C:ASP459
|
4.8
|
22.3
|
1.0
|
|
C
|
C:CO31002
|
4.8
|
29.9
|
1.0
|
|
Zinc binding site 6 out
of 24 in 3kqz
Go back to
Zinc Binding Sites List in 3kqz
Zinc binding site 6 out
of 24 in the Structure of A Protease 2
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Structure of A Protease 2 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn1004
b:25.7
occ:1.00
|
OD1
|
C:ASP459
|
1.9
|
31.6
|
1.0
|
|
OD2
|
C:ASP379
|
2.0
|
24.6
|
1.0
|
|
OE1
|
C:GLU461
|
2.0
|
21.1
|
1.0
|
|
O
|
C:ASP459
|
2.5
|
22.3
|
1.0
|
|
CD
|
C:GLU461
|
2.8
|
22.2
|
1.0
|
|
ZN
|
C:ZN1001
|
2.8
|
23.9
|
1.0
|
|
CG
|
C:ASP379
|
2.9
|
24.4
|
1.0
|
|
OE2
|
C:GLU461
|
3.0
|
17.4
|
1.0
|
|
CG
|
C:ASP459
|
3.1
|
26.3
|
1.0
|
|
OD1
|
C:ASP379
|
3.1
|
23.9
|
1.0
|
|
C
|
C:ASP459
|
3.1
|
20.2
|
1.0
|
|
CA
|
C:ASP459
|
3.4
|
18.4
|
1.0
|
|
O1
|
C:CO31002
|
3.8
|
27.4
|
1.0
|
|
CB
|
C:ASP459
|
3.8
|
19.3
|
1.0
|
|
OD2
|
C:ASP459
|
4.0
|
29.0
|
1.0
|
|
NZ
|
C:LYS386
|
4.1
|
25.1
|
1.0
|
|
N
|
C:GLU461
|
4.2
|
21.3
|
1.0
|
|
CE
|
C:LYS386
|
4.2
|
22.7
|
1.0
|
|
N
|
C:ALA460
|
4.3
|
21.0
|
1.0
|
|
OD2
|
C:ASP399
|
4.3
|
28.9
|
1.0
|
|
CB
|
C:ASP379
|
4.3
|
22.4
|
1.0
|
|
CG
|
C:GLU461
|
4.3
|
21.1
|
1.0
|
|
ND2
|
C:ASN432
|
4.4
|
16.4
|
1.0
|
|
NZ
|
C:LYS374
|
4.5
|
24.4
|
1.0
|
|
CA
|
C:ALA460
|
4.7
|
21.1
|
1.0
|
|
N
|
C:ASP459
|
4.7
|
18.7
|
1.0
|
|
CA
|
C:GLY381
|
4.8
|
21.0
|
1.0
|
|
CB
|
C:GLU461
|
4.8
|
23.4
|
1.0
|
|
C
|
C:CO31002
|
4.9
|
29.9
|
1.0
|
|
O
|
C:THR458
|
4.9
|
19.7
|
1.0
|
|
C
|
C:ALA460
|
4.9
|
20.5
|
1.0
|
|
Zinc binding site 7 out
of 24 in 3kqz
Go back to
Zinc Binding Sites List in 3kqz
Zinc binding site 7 out
of 24 in the Structure of A Protease 2
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of Structure of A Protease 2 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn1001
b:28.3
occ:1.00
|
OE2
|
D:GLU461
|
2.0
|
18.9
|
1.0
|
|
NZ
|
D:LYS374
|
2.0
|
22.9
|
1.0
|
|
OD2
|
D:ASP399
|
2.1
|
29.5
|
1.0
|
|
OD2
|
D:ASP379
|
2.8
|
33.5
|
1.0
|
|
CG
|
D:ASP399
|
2.9
|
27.8
|
1.0
|
|
CE
|
D:LYS374
|
2.9
|
17.9
|
1.0
|
|
ZN
|
D:ZN1004
|
3.0
|
29.8
|
1.0
|
|
CD
|
D:GLU461
|
3.0
|
19.9
|
1.0
|
|
OD1
|
D:ASP399
|
3.0
|
21.9
|
1.0
|
|
OE1
|
D:GLU461
|
3.3
|
20.4
|
1.0
|
|
C15
|
D:1PE23
|
3.3
|
18.4
|
1.0
|
|
CG
|
D:ASP379
|
3.5
|
23.7
|
1.0
|
|
O1
|
D:CO31002
|
3.6
|
25.1
|
1.0
|
|
C25
|
D:1PE23
|
3.9
|
30.4
|
1.0
|
|
CB
|
D:ASP379
|
4.0
|
20.7
|
1.0
|
|
O
|
D:THR486
|
4.2
|
26.2
|
1.0
|
|
OD1
|
D:ASP379
|
4.3
|
19.2
|
1.0
|
|
CD
|
D:LYS374
|
4.3
|
17.0
|
1.0
|
|
CG
|
D:GLU461
|
4.3
|
19.7
|
1.0
|
|
CB
|
D:ASP399
|
4.4
|
23.4
|
1.0
|
|
N
|
D:GLY462
|
4.4
|
23.2
|
1.0
|
|
CG1
|
D:ILE376
|
4.4
|
24.6
|
1.0
|
|
O
|
D:ASP459
|
4.6
|
24.4
|
1.0
|
|
CA
|
D:GLY462
|
4.6
|
21.0
|
1.0
|
|
CB
|
D:ILE376
|
4.7
|
22.3
|
1.0
|
|
OD1
|
D:ASP459
|
4.7
|
23.0
|
1.0
|
|
CG2
|
D:ILE376
|
4.8
|
13.9
|
1.0
|
|
C
|
D:CO31002
|
4.8
|
26.1
|
1.0
|
|
Zinc binding site 8 out
of 24 in 3kqz
Go back to
Zinc Binding Sites List in 3kqz
Zinc binding site 8 out
of 24 in the Structure of A Protease 2
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of Structure of A Protease 2 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn1004
b:29.8
occ:1.00
|
OE1
|
D:GLU461
|
1.9
|
20.4
|
1.0
|
|
OD1
|
D:ASP459
|
1.9
|
23.0
|
1.0
|
|
OD2
|
D:ASP379
|
2.0
|
33.5
|
1.0
|
|
O
|
D:ASP459
|
2.3
|
24.4
|
1.0
|
|
CD
|
D:GLU461
|
2.8
|
19.9
|
1.0
|
|
CG
|
D:ASP379
|
2.9
|
23.7
|
1.0
|
|
ZN
|
D:ZN1001
|
3.0
|
28.3
|
1.0
|
|
C
|
D:ASP459
|
3.0
|
22.5
|
1.0
|
|
OD1
|
D:ASP379
|
3.1
|
19.2
|
1.0
|
|
CG
|
D:ASP459
|
3.1
|
26.9
|
1.0
|
|
OE2
|
D:GLU461
|
3.2
|
18.9
|
1.0
|
|
CA
|
D:ASP459
|
3.4
|
23.4
|
1.0
|
|
C15
|
D:1PE23
|
3.5
|
18.4
|
1.0
|
|
CB
|
D:ASP459
|
3.8
|
22.1
|
1.0
|
|
NZ
|
D:LYS386
|
4.1
|
29.1
|
1.0
|
|
OD2
|
D:ASP459
|
4.1
|
20.8
|
1.0
|
|
N
|
D:ALA460
|
4.1
|
22.2
|
1.0
|
|
O1
|
D:CO31002
|
4.1
|
25.1
|
1.0
|
|
CE
|
D:LYS386
|
4.2
|
25.1
|
1.0
|
|
CG
|
D:GLU461
|
4.2
|
19.7
|
1.0
|
|
CB
|
D:ASP379
|
4.2
|
20.7
|
1.0
|
|
ND2
|
D:ASN432
|
4.3
|
21.3
|
1.0
|
|
N
|
D:GLU461
|
4.3
|
23.7
|
1.0
|
|
OD2
|
D:ASP399
|
4.4
|
29.5
|
1.0
|
|
CA
|
D:GLY381
|
4.6
|
24.8
|
1.0
|
|
CA
|
D:ALA460
|
4.6
|
21.4
|
1.0
|
|
NZ
|
D:LYS374
|
4.7
|
22.9
|
1.0
|
|
CB
|
D:GLU461
|
4.7
|
21.4
|
1.0
|
|
O
|
D:THR458
|
4.7
|
22.7
|
1.0
|
|
N
|
D:ASP459
|
4.8
|
22.5
|
1.0
|
|
C25
|
D:1PE23
|
4.9
|
30.4
|
1.0
|
|
C
|
D:CO31002
|
4.9
|
26.1
|
1.0
|
|
N
|
D:GLY462
|
5.0
|
23.2
|
1.0
|
|
C
|
D:ALA460
|
5.0
|
23.2
|
1.0
|
|
Zinc binding site 9 out
of 24 in 3kqz
Go back to
Zinc Binding Sites List in 3kqz
Zinc binding site 9 out
of 24 in the Structure of A Protease 2
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 9 of Structure of A Protease 2 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Zn1001
b:27.3
occ:1.00
|
OD2
|
E:ASP399
|
1.7
|
22.2
|
1.0
|
|
OE2
|
E:GLU461
|
2.1
|
22.6
|
1.0
|
|
NZ
|
E:LYS374
|
2.1
|
20.8
|
1.0
|
|
OD2
|
E:ASP379
|
2.6
|
28.1
|
1.0
|
|
CG
|
E:ASP399
|
2.8
|
21.7
|
1.0
|
|
ZN
|
E:ZN1004
|
2.9
|
31.6
|
1.0
|
|
CE
|
E:LYS374
|
3.0
|
23.4
|
1.0
|
|
CD
|
E:GLU461
|
3.0
|
17.5
|
1.0
|
|
OD1
|
E:ASP399
|
3.1
|
21.7
|
1.0
|
|
OE1
|
E:GLU461
|
3.3
|
24.1
|
1.0
|
|
CG
|
E:ASP379
|
3.5
|
24.5
|
1.0
|
|
O3
|
E:CO31002
|
3.6
|
31.4
|
1.0
|
|
CB
|
E:ASP379
|
4.0
|
22.6
|
1.0
|
|
CB
|
E:ASP399
|
4.2
|
22.0
|
1.0
|
|
O
|
E:THR486
|
4.3
|
23.5
|
1.0
|
|
N
|
E:GLY462
|
4.4
|
22.6
|
1.0
|
|
OD1
|
E:ASP379
|
4.4
|
24.4
|
1.0
|
|
CG
|
E:GLU461
|
4.4
|
20.7
|
1.0
|
|
CD
|
E:LYS374
|
4.5
|
21.5
|
1.0
|
|
O
|
E:ASP459
|
4.5
|
24.8
|
1.0
|
|
CG1
|
E:ILE376
|
4.5
|
21.8
|
1.0
|
|
OD1
|
E:ASP459
|
4.5
|
24.4
|
1.0
|
|
CA
|
E:GLY462
|
4.7
|
21.1
|
1.0
|
|
CB
|
E:ILE376
|
4.7
|
24.9
|
1.0
|
|
CG2
|
E:ILE376
|
4.8
|
22.9
|
1.0
|
|
C
|
E:CO31002
|
4.8
|
28.4
|
1.0
|
|
Zinc binding site 10 out
of 24 in 3kqz
Go back to
Zinc Binding Sites List in 3kqz
Zinc binding site 10 out
of 24 in the Structure of A Protease 2
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 10 of Structure of A Protease 2 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Zn1004
b:31.6
occ:1.00
|
OD1
|
E:ASP459
|
1.9
|
24.4
|
1.0
|
|
OE1
|
E:GLU461
|
2.0
|
24.1
|
1.0
|
|
OD2
|
E:ASP379
|
2.0
|
28.1
|
1.0
|
|
O
|
E:ASP459
|
2.2
|
24.8
|
1.0
|
|
CD
|
E:GLU461
|
2.9
|
17.5
|
1.0
|
|
ZN
|
E:ZN1001
|
2.9
|
27.3
|
1.0
|
|
CG
|
E:ASP379
|
2.9
|
24.5
|
1.0
|
|
CG
|
E:ASP459
|
3.0
|
21.6
|
1.0
|
|
C
|
E:ASP459
|
3.0
|
24.6
|
1.0
|
|
OE2
|
E:GLU461
|
3.2
|
22.6
|
1.0
|
|
OD1
|
E:ASP379
|
3.3
|
24.4
|
1.0
|
|
CA
|
E:ASP459
|
3.3
|
24.2
|
1.0
|
|
CB
|
E:ASP459
|
3.7
|
23.0
|
1.0
|
|
OD2
|
E:ASP459
|
4.0
|
25.4
|
1.0
|
|
OD2
|
E:ASP399
|
4.1
|
22.2
|
1.0
|
|
O3
|
E:CO31002
|
4.1
|
31.4
|
1.0
|
|
NZ
|
E:LYS386
|
4.1
|
19.6
|
1.0
|
|
N
|
E:ALA460
|
4.1
|
24.2
|
1.0
|
|
N
|
E:GLU461
|
4.2
|
22.1
|
1.0
|
|
CB
|
E:ASP379
|
4.3
|
22.6
|
1.0
|
|
CG
|
E:GLU461
|
4.3
|
20.7
|
1.0
|
|
CE
|
E:LYS386
|
4.3
|
23.6
|
1.0
|
|
ND2
|
E:ASN432
|
4.3
|
16.1
|
1.0
|
|
N
|
E:ASP459
|
4.6
|
25.3
|
1.0
|
|
CA
|
E:ALA460
|
4.6
|
23.8
|
1.0
|
|
CA
|
E:GLY381
|
4.7
|
21.5
|
1.0
|
|
NZ
|
E:LYS374
|
4.7
|
20.8
|
1.0
|
|
O
|
E:THR458
|
4.8
|
28.2
|
1.0
|
|
CB
|
E:GLU461
|
4.8
|
19.1
|
1.0
|
|
C
|
E:ALA460
|
5.0
|
23.7
|
1.0
|
|
Reference:
S.Mcgowan,
C.A.Oellig,
W.A.Birru,
T.T.Caradoc-Davies,
C.M.Stack,
J.Lowther,
T.Skinner-Adams,
A.Mucha,
P.Kafarski,
J.Grembecka,
K.R.Trenholme,
A.M.Buckle,
D.L.Gardiner,
J.P.Dalton,
J.C.Whisstock.
Structure of the Plasmodium Falciparum M17 Aminopeptidase and Significance For the Design of Drugs Targeting the Neutral Exopeptidases Proc.Natl.Acad.Sci.Usa V. 107 2449 2010.
ISSN: ISSN 0027-8424
PubMed: 20133789
DOI: 10.1073/PNAS.0911813107
Page generated: Sat Oct 26 07:59:53 2024
|
