Zinc in PDB 2vp7: Decoding of Methylated Histone H3 Tail By the Pygo-BCL9 Wnt Signaling Complex

The structure of Decoding of Methylated Histone H3 Tail By the Pygo-BCL9 Wnt Signaling Complex, PDB code: 2vp7 was solved by M.Fiedler, M.J.Sanchez-Barrena, M.Nekrasov, J.Mieszczanek, V.Rybin, J.Muller, P.Evans, M.Bienz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	56.70 / 1.65
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	32.650, 72.060, 91.810, 90.00, 90.00, 90.00
R / Rfree (%)	21.8 / 26.7

The binding sites of Zinc atom in the Decoding of Methylated Histone H3 Tail By the Pygo-BCL9 Wnt Signaling Complex (pdb code 2vp7). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Decoding of Methylated Histone H3 Tail By the Pygo-BCL9 Wnt Signaling Complex, PDB code: 2vp7:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Decoding of Methylated Histone H3 Tail By the Pygo-BCL9 Wnt Signaling Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Decoding of Methylated Histone H3 Tail By the Pygo-BCL9 Wnt Signaling Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1399 b:19.4 occ:1.00 ND1 A:HIS368 2.0 18.4 1.0 SG A:CYS371 2.3 20.1 1.0 SG A:CYS343 2.3 20.8 1.0 SG A:CYS346 2.4 20.9 1.0 CE1 A:HIS368 2.9 19.4 1.0 CB A:CYS343 3.0 23.4 1.0 CG A:HIS368 3.1 16.7 1.0 CB A:CYS371 3.3 20.0 1.0 CB A:CYS346 3.3 25.3 1.0 CB A:HIS368 3.5 15.4 1.0 N A:CYS346 3.8 26.1 1.0 NE2 A:HIS368 4.1 24.0 1.0 N A:HIS368 4.1 16.8 1.0 CD2 A:HIS368 4.1 20.6 1.0 CA A:CYS346 4.2 25.3 1.0 CA A:HIS368 4.4 15.8 1.0 CA A:CYS343 4.5 23.4 1.0 CA A:CYS371 4.7 18.9 1.0 CB A:ILE345 4.8 27.1 1.0 C A:ILE345 4.9 26.9 1.0 N A:CYS371 5.0 18.9 1.0 C A:CYS346 5.0 25.4 1.0

Zinc binding site 2 out of 2 in the Decoding of Methylated Histone H3 Tail By the Pygo-BCL9 Wnt Signaling Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Decoding of Methylated Histone H3 Tail By the Pygo-BCL9 Wnt Signaling Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1400 b:36.6 occ:1.00 SG A:CYS392 2.2 26.1 1.0 SG A:CYS363 2.2 43.8 1.0 SG A:CYS359 2.2 30.1 1.0 SG A:CYS395 2.6 45.9 1.0 CB A:CYS392 3.1 32.8 1.0 CB A:CYS359 3.1 29.8 1.0 CB A:CYS363 3.2 41.3 1.0 CB A:CYS395 3.4 45.1 1.0 N A:CYS363 3.8 41.4 1.0 CA A:CYS363 4.0 41.2 1.0 N A:CYS392 4.0 28.7 1.0 CA A:CYS392 4.1 31.4 1.0 CA A:CYS359 4.5 29.8 1.0 N A:CYS395 4.5 44.9 1.0 CA A:CYS395 4.6 45.0 1.0 N A:GLN364 4.7 38.7 1.0 N A:SER362 4.8 40.2 1.0 C A:CYS363 4.8 40.4 1.0 C A:SER362 5.0 41.4 1.0 C A:CYS359 5.0 31.1 1.0 CE A:LYS365 5.0 36.7 1.0 C A:CYS392 5.0 33.6 1.0

M.Fiedler, M.J.Sanchez-Barrena, M.Nekrasov, J.Mieszczanek, V.Rybin, J.Muller, P.Evans, M.Bienz. Decoding of Methylated Histone H3 Tail By the Pygo- BCL9 Wnt Signaling Complex. Mol.Cell V. 30 507 2008.
ISSN: ISSN 1097-2765
PubMed: 18498752
DOI: 10.1016/J.MOLCEL.2008.03.011