Zinc in PDB 2vk0: Crystal Structure Form Ultalente Insulin Microcrystals

The structure of Crystal Structure Form Ultalente Insulin Microcrystals, PDB code: 2vk0 was solved by A.Wagner, J.Diez, C.Schulze-Briese, G.Schluckebier, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.52 / 2.20
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	81.030, 81.030, 33.900, 90.00, 90.00, 120.00
R / Rfree (%)	24 / 28.2

The binding sites of Zinc atom in the Crystal Structure Form Ultalente Insulin Microcrystals (pdb code 2vk0). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure Form Ultalente Insulin Microcrystals, PDB code: 2vk0:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Crystal Structure Form Ultalente Insulin Microcrystals


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure Form Ultalente Insulin Microcrystals within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1031 b:19.4 occ:0.33 O B:HOH2025 1.9 18.3 0.3 NE2 B:HIS10 2.0 20.4 1.0 CE1 B:HIS10 2.9 20.6 1.0 CD2 B:HIS10 3.0 20.4 1.0 ND1 B:HIS10 4.0 20.6 1.0 CG B:HIS10 4.1 20.4 1.0 O B:HOH2001 4.8 27.9 1.0

Zinc binding site 2 out of 4 in the Crystal Structure Form Ultalente Insulin Microcrystals


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure Form Ultalente Insulin Microcrystals within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1030 b:13.0 occ:0.33 NE2 D:HIS10 2.0 21.0 1.0 CE1 D:HIS10 2.9 21.4 1.0 CD2 D:HIS10 3.1 21.1 1.0 ND1 D:HIS10 4.1 21.4 1.0 CG D:HIS10 4.2 21.3 1.0 O D:HOH2005 4.5 36.2 1.0 O D:HOH2007 4.6 32.5 1.0

Zinc binding site 3 out of 4 in the Crystal Structure Form Ultalente Insulin Microcrystals


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure Form Ultalente Insulin Microcrystals within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1031 b:15.2 occ:0.33 OE1 D:GLU13 1.9 22.6 1.0 O D:HOH2016 2.0 34.5 1.0 O D:HOH2017 2.1 26.3 1.0 ND1 D:HIS10 2.5 21.4 1.0 CE1 D:HIS10 3.0 21.4 1.0 CD D:GLU13 3.1 21.5 1.0 ZN D:ZN1032 3.2 28.0 0.3 OE2 D:GLU13 3.7 22.5 1.0 CG D:HIS10 3.7 21.3 1.0 NE2 D:HIS10 4.2 21.0 1.0 CG D:GLU13 4.3 21.3 1.0 CA D:HIS10 4.3 21.6 1.0 CB D:HIS10 4.3 21.5 1.0 CB D:GLU13 4.5 21.0 1.0 CD2 D:HIS10 4.6 21.1 1.0 OE2 B:GLU13 4.8 21.9 1.0 N D:HIS10 4.9 21.8 1.0

Zinc binding site 4 out of 4 in the Crystal Structure Form Ultalente Insulin Microcrystals


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure Form Ultalente Insulin Microcrystals within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1032 b:28.0 occ:0.33 O D:HOH2017 2.0 26.3 1.0 OE2 D:GLU13 2.2 22.5 1.0 CD D:GLU13 3.0 21.5 1.0 OE1 D:GLU13 3.0 22.6 1.0 ZN D:ZN1031 3.2 15.2 0.3 OE2 B:GLU13 3.9 21.9 1.0 O D:HOH2010 4.1 26.0 1.0 O D:HOH2016 4.3 34.5 1.0 CG D:GLU13 4.4 21.3 1.0 CD B:GLU13 4.7 21.1 1.0 OE1 B:GLU13 4.9 21.8 1.0

A.Wagner, J.Diez, C.Schulze-Briese, G.Schluckebier. Crystal Structure of Ultralente--A Microcrystalline Insulin Suspension. Proteins V. 74 1018 2009.
ISSN: ISSN 0887-3585
PubMed: 18767151
DOI: 10.1002/PROT.22213