Atomistry » Zinc » PDB 2qla-2qym » 2qvv
Atomistry »
  Zinc »
    PDB 2qla-2qym »
      2qvv »

Zinc in PDB 2qvv: Porcine Liver Fructose-1,6-Bisphosphatase Cocrystallized with Fru-2,6- P2 and ZN2+, I(T)-State

Enzymatic activity of Porcine Liver Fructose-1,6-Bisphosphatase Cocrystallized with Fru-2,6- P2 and ZN2+, I(T)-State

All present enzymatic activity of Porcine Liver Fructose-1,6-Bisphosphatase Cocrystallized with Fru-2,6- P2 and ZN2+, I(T)-State:
3.1.3.11;

Protein crystallography data

The structure of Porcine Liver Fructose-1,6-Bisphosphatase Cocrystallized with Fru-2,6- P2 and ZN2+, I(T)-State, PDB code: 2qvv was solved by J.K.Hines, X.Chen, J.C.Nix, H.J.Fromm, R.B.Honzatko, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.33 / 2.03
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 59.038, 165.709, 79.167, 90.00, 90.00, 90.00
R / Rfree (%) 20 / 23.4

Zinc Binding Sites:

The binding sites of Zinc atom in the Porcine Liver Fructose-1,6-Bisphosphatase Cocrystallized with Fru-2,6- P2 and ZN2+, I(T)-State (pdb code 2qvv). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Porcine Liver Fructose-1,6-Bisphosphatase Cocrystallized with Fru-2,6- P2 and ZN2+, I(T)-State, PDB code: 2qvv:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 2qvv

Go back to Zinc Binding Sites List in 2qvv
Zinc binding site 1 out of 2 in the Porcine Liver Fructose-1,6-Bisphosphatase Cocrystallized with Fru-2,6- P2 and ZN2+, I(T)-State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Porcine Liver Fructose-1,6-Bisphosphatase Cocrystallized with Fru-2,6- P2 and ZN2+, I(T)-State within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn403

b:22.0
occ:1.00
OD2 A:ASP118 2.1 18.0 1.0
OE2 A:GLU280 2.2 21.4 1.0
O A:HOH613 2.2 20.4 1.0
OD2 A:ASP121 2.2 20.9 1.0
O1 A:FDP402 2.3 22.9 1.0
CG A:ASP118 3.1 20.3 1.0
CG A:ASP121 3.2 19.9 1.0
CD A:GLU280 3.2 23.5 1.0
OD1 A:ASP118 3.4 21.7 1.0
CB A:ASP121 3.4 19.0 1.0
C1 A:FDP402 3.5 18.7 1.0
CA A:ASP121 3.6 21.6 1.0
CG A:GLU280 3.7 21.7 1.0
NH1 A:ARG276 3.8 26.6 1.0
O3 A:FDP402 3.9 16.2 1.0
N A:GLY122 4.3 21.4 1.0
OD1 A:ASP121 4.3 19.9 1.0
OE1 A:GLU280 4.3 23.1 1.0
C3 A:FDP402 4.3 16.7 1.0
O A:HOH641 4.3 37.7 1.0
CB A:ASP118 4.4 20.6 1.0
C2 A:FDP402 4.4 18.9 1.0
O2P A:FDP402 4.5 23.4 1.0
C A:ASP121 4.5 22.6 1.0
N A:ASP121 4.7 23.2 1.0
CD1 A:ILE135 4.9 22.0 1.0
O2 A:FDP402 4.9 19.1 1.0
CZ A:ARG276 5.0 27.7 1.0

Zinc binding site 2 out of 2 in 2qvv

Go back to Zinc Binding Sites List in 2qvv
Zinc binding site 2 out of 2 in the Porcine Liver Fructose-1,6-Bisphosphatase Cocrystallized with Fru-2,6- P2 and ZN2+, I(T)-State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Porcine Liver Fructose-1,6-Bisphosphatase Cocrystallized with Fru-2,6- P2 and ZN2+, I(T)-State within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn339

b:19.3
occ:1.00
OD2 B:ASP118 2.0 15.3 1.0
OE1 B:GLU280 2.1 16.2 1.0
OD2 B:ASP121 2.1 14.8 1.0
O B:HOH673 2.1 19.3 1.0
O1 B:FDP338 2.3 20.5 1.0
CG B:ASP118 3.0 17.4 1.0
CG B:ASP121 3.1 17.7 1.0
CD B:GLU280 3.1 19.9 1.0
CB B:ASP121 3.4 17.8 1.0
OD1 B:ASP118 3.5 18.9 1.0
C1 B:FDP338 3.5 19.3 1.0
CG B:GLU280 3.6 17.4 1.0
CA B:ASP121 3.6 19.6 1.0
NH2 B:ARG276 3.7 19.3 1.0
O3 B:FDP338 4.0 18.8 1.0
O B:HOH510 4.2 30.9 1.0
OD1 B:ASP121 4.2 17.4 1.0
OE2 B:GLU280 4.2 20.2 1.0
N B:GLY122 4.3 21.4 1.0
CB B:ASP118 4.3 15.4 1.0
C3 B:FDP338 4.4 18.7 1.0
O3P B:FDP338 4.4 23.0 1.0
C2 B:FDP338 4.4 18.7 1.0
C B:ASP121 4.5 20.9 1.0
N B:ASP121 4.7 20.0 1.0
CD1 B:ILE135 4.8 18.1 1.0
CG B:GLU97 4.9 24.8 1.0
CZ B:ARG276 4.9 24.1 1.0
O2 B:FDP338 5.0 19.4 1.0

Reference:

J.K.Hines, X.Chen, J.C.Nix, H.J.Fromm, R.B.Honzatko. Structures of Mammalian and Bacterial Fructose-1,6-Bisphosphatase Reveal the Basis For Synergism in Amp/Fructose 2,6-Bisphosphate Inhibition J.Biol.Chem. V. 282 36121 2007.
ISSN: ISSN 0021-9258
PubMed: 17933867
DOI: 10.1074/JBC.M707302200
Page generated: Wed Dec 16 03:51:05 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy