Zinc in PDB 2qmz: Quinone Reductase 2 in Complex with Dopamine

All present enzymatic activity of Quinone Reductase 2 in Complex with Dopamine:
1.10.99.2;

The structure of Quinone Reductase 2 in Complex with Dopamine, PDB code: 2qmz was solved by Y.Fu, L.Buryanovskyy, Z.Zhang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.10
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	83.442, 106.448, 56.533, 90.00, 90.00, 90.00
R / Rfree (%)	19.3 / 23.8

The binding sites of Zinc atom in the Quinone Reductase 2 in Complex with Dopamine (pdb code 2qmz). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Quinone Reductase 2 in Complex with Dopamine, PDB code: 2qmz:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Quinone Reductase 2 in Complex with Dopamine


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Quinone Reductase 2 in Complex with Dopamine within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn231 b:30.3 occ:1.00 ND1 A:HIS173 2.2 23.5 1.0 SG A:CYS222 2.3 29.5 1.0 O A:CYS222 2.4 31.3 1.0 CD2 A:HIS177 2.7 33.9 1.0 CB A:CYS222 2.8 31.5 1.0 CG A:HIS177 3.0 33.4 1.0 CG A:HIS173 3.1 21.6 1.0 C A:CYS222 3.1 31.5 1.0 CE1 A:HIS173 3.2 23.6 1.0 CB A:HIS177 3.2 28.4 1.0 CB A:HIS173 3.4 19.5 1.0 CA A:HIS173 3.6 20.3 1.0 CA A:CYS222 3.6 31.8 1.0 NE2 A:HIS177 3.6 35.7 1.0 ND1 A:HIS177 4.0 35.2 1.0 N A:THR223 4.2 30.9 1.0 O B:HOH608 4.2 53.0 1.0 CE1 A:HIS177 4.2 35.2 1.0 CD2 A:HIS173 4.3 23.0 1.0 NE2 A:HIS173 4.3 24.4 1.0 N A:HIS173 4.5 19.7 1.0 C A:HIS173 4.5 19.9 1.0 O A:HIS173 4.6 22.5 1.0 O A:GLN172 4.6 21.1 1.0 CA A:THR223 4.7 30.5 1.0 N A:CYS222 4.7 33.4 1.0 CA A:HIS177 4.8 26.9 1.0 C A:GLN172 4.9 19.1 1.0 CE1 A:TYR132 4.9 40.3 1.0 CE1 A:HIS227 5.0 29.4 1.0

Zinc binding site 2 out of 2 in the Quinone Reductase 2 in Complex with Dopamine


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Quinone Reductase 2 in Complex with Dopamine within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn232 b:22.9 occ:1.00 ND1 B:HIS173 2.2 14.5 1.0 O B:CYS222 2.3 18.2 1.0 ND1 B:HIS177 2.3 21.4 1.0 SG B:CYS222 2.4 21.1 1.0 CB B:CYS222 2.8 21.1 1.0 C B:CYS222 3.0 18.8 1.0 CG B:HIS173 3.1 14.6 1.0 CG B:HIS177 3.2 19.6 1.0 CE1 B:HIS173 3.2 13.6 1.0 CB B:HIS173 3.3 13.2 1.0 CB B:HIS177 3.3 13.9 1.0 CE1 B:HIS177 3.4 20.9 1.0 CA B:CYS222 3.5 20.0 1.0 CA B:HIS173 3.5 15.1 1.0 N B:THR223 4.1 18.6 1.0 CD2 B:HIS173 4.3 14.1 1.0 NE2 B:HIS173 4.3 15.3 1.0 CD2 B:HIS177 4.4 21.6 1.0 NE2 B:HIS177 4.4 21.9 1.0 N B:HIS173 4.4 14.4 1.0 C B:HIS173 4.6 15.4 1.0 O B:GLN172 4.6 12.9 1.0 CA B:THR223 4.6 18.0 1.0 N B:CYS222 4.7 20.6 1.0 O B:HIS173 4.7 14.5 1.0 CA B:HIS177 4.8 14.2 1.0 C B:GLN172 4.9 13.7 1.0

Y.Fu, L.Buryanovskyy, Z.Zhang. Quinone Reductase 2 Regulates Catecholamine Oxidation To Be Published.