Zinc in PDB 2qiu: Structure of Human Arg-Insulin

The structure of Structure of Human Arg-Insulin, PDB code: 2qiu was solved by R.Sreekanth, V.Pattabhi, S.S.Rajan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.26 / 2.00
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	80.491, 80.491, 37.640, 90.00, 90.00, 120.00
R / Rfree (%)	19.7 / 24.9

The binding sites of Zinc atom in the Structure of Human Arg-Insulin (pdb code 2qiu). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Human Arg-Insulin, PDB code: 2qiu:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of Human Arg-Insulin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Human Arg-Insulin within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn101 b:35.2 occ:0.33 NE2 B:HIS10 2.1 29.5 1.0 O B:HOH108 2.5 7.6 0.3 CE1 B:HIS10 2.9 21.4 1.0 CD2 B:HIS10 3.2 18.5 1.0 ND1 B:HIS10 4.1 21.2 1.0 CG B:HIS10 4.2 22.5 1.0 O B:LEU6 4.3 35.2 1.0 O B:HOH110 4.6 40.8 1.0 CG B:LEU6 5.0 28.4 1.0

Zinc binding site 2 out of 2 in the Structure of Human Arg-Insulin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Human Arg-Insulin within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn102 b:39.4 occ:0.33 NE2 D:HIS10 2.1 30.1 1.0 O D:HOH111 2.5 13.3 0.3 CD2 D:HIS10 3.0 30.0 1.0 CE1 D:HIS10 3.1 31.9 1.0 CG D:HIS10 4.2 40.0 1.0 ND1 D:HIS10 4.2 31.8 1.0 O D:HOH104 4.2 37.8 1.0

R.Sreekanth, V.Pattabhi, S.S.Rajan. Structural Interpretation of Reduced Insulin Activity As Seen in the Crystal Structure of Human Arg-Insulin Biochimie V. 90 467 2008.
ISSN: ISSN 0300-9084
PubMed: 18029081
DOI: 10.1016/J.BIOCHI.2007.09.012