Atomistry » Zinc » PDB 2omg-2ovx » 2omi
Atomistry »
  Zinc »
    PDB 2omg-2ovx »
      2omi »

Zinc in PDB 2omi: Structure of Human Insulin Cocrystallized with Protamine

Protein crystallography data

The structure of Structure of Human Insulin Cocrystallized with Protamine, PDB code: 2omi was solved by M.Norrman, G.Schluckebier, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.10 / 2.24
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 60.520, 61.840, 86.000, 90.00, 90.00, 90.00
R / Rfree (%) 19.9 / 26.8

Other elements in 2omi:

The structure of Structure of Human Insulin Cocrystallized with Protamine also contains other interesting chemical elements:

Chlorine (Cl) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Structure of Human Insulin Cocrystallized with Protamine (pdb code 2omi). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Human Insulin Cocrystallized with Protamine, PDB code: 2omi:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 2omi

Go back to Zinc Binding Sites List in 2omi
Zinc binding site 1 out of 2 in the Structure of Human Insulin Cocrystallized with Protamine


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Human Insulin Cocrystallized with Protamine within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn202

b:13.6
occ:1.00
NE2 F:HIS10 2.0 12.5 1.0
NE2 B:HIS10 2.0 18.6 1.0
CL B:CL402 2.1 14.5 1.0
NE2 D:HIS10 2.1 12.2 1.0
CE1 B:HIS10 2.9 17.7 1.0
CD2 F:HIS10 2.9 14.8 1.0
CE1 F:HIS10 3.0 15.0 1.0
CE1 D:HIS10 3.0 13.6 1.0
CD2 B:HIS10 3.1 12.7 1.0
CD2 D:HIS10 3.1 15.4 1.0
ND1 B:HIS10 4.0 15.7 1.0
ND1 F:HIS10 4.1 17.1 1.0
CG F:HIS10 4.1 11.7 1.0
CG B:HIS10 4.1 13.9 1.0
ND1 D:HIS10 4.1 13.2 1.0
CG D:HIS10 4.2 13.8 1.0
O B:LEU6 4.6 14.7 1.0
CB F:LEU6 4.7 14.9 1.0
O F:LEU6 4.8 14.9 1.0
O D:LEU6 4.8 15.7 1.0
CB B:LEU6 4.9 12.7 1.0
CB D:LEU6 4.9 12.4 1.0

Zinc binding site 2 out of 2 in 2omi

Go back to Zinc Binding Sites List in 2omi
Zinc binding site 2 out of 2 in the Structure of Human Insulin Cocrystallized with Protamine


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Human Insulin Cocrystallized with Protamine within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Zn201

b:15.6
occ:1.00
NE2 L:HIS10 1.9 15.0 1.0
NE2 J:HIS10 2.0 14.7 1.0
CL J:CL401 2.1 12.7 1.0
NE2 H:HIS10 2.2 19.5 1.0
CE1 L:HIS10 2.8 17.4 1.0
CE1 J:HIS10 2.8 11.2 1.0
CD2 L:HIS10 3.0 11.8 1.0
CD2 H:HIS10 3.1 14.9 1.0
CD2 J:HIS10 3.1 11.2 1.0
CE1 H:HIS10 3.3 19.8 1.0
ND1 L:HIS10 3.9 20.2 1.0
ND1 J:HIS10 4.0 9.6 1.0
CG L:HIS10 4.1 12.2 1.0
CG J:HIS10 4.2 12.4 1.0
CG H:HIS10 4.3 15.0 1.0
ND1 H:HIS10 4.3 20.0 1.0
O H:LEU6 4.5 17.1 1.0
O J:LEU6 4.6 15.3 1.0
O L:LEU6 4.8 16.0 1.0
CB L:LEU6 4.8 14.1 1.0
CB J:LEU6 4.8 12.9 1.0
CB H:LEU6 4.9 14.3 1.0

Reference:

M.Norrman, F.Hubalek, G.Schluckebier. Structural Characterization of Insulin Nph Formulations. Eur.J.Pharm.Sci. V. 30 414 2007.
PubMed: 17339105
DOI: 10.1016/J.EJPS.2007.01.003
Page generated: Thu Oct 17 02:41:54 2024

Last articles

Zn in 9FD2
Zn in 9GUW
Zn in 9GUX
Zn in 9F7C
Zn in 9GUR
Zn in 9F7A
Zn in 9DDE
Zn in 9DBY
Zn in 9EBZ
Zn in 9DGG
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy