Atomistry » Zinc » PDB 2g2n-2gc3 » 2g45
Atomistry »
  Zinc »
    PDB 2g2n-2gc3 »
      2g45 »

Zinc in PDB 2g45: Co-Crystal Structure of Znf Ubp Domain From the Deubiquitinating Enzyme Isopeptidase T (Isot) in Complex with Ubiquitin

Enzymatic activity of Co-Crystal Structure of Znf Ubp Domain From the Deubiquitinating Enzyme Isopeptidase T (Isot) in Complex with Ubiquitin

All present enzymatic activity of Co-Crystal Structure of Znf Ubp Domain From the Deubiquitinating Enzyme Isopeptidase T (Isot) in Complex with Ubiquitin:
3.1.2.15;

Protein crystallography data

The structure of Co-Crystal Structure of Znf Ubp Domain From the Deubiquitinating Enzyme Isopeptidase T (Isot) in Complex with Ubiquitin, PDB code: 2g45 was solved by F.E.Reyes-Turcu, J.R.Horton, J.E.Mullally, A.Heroux, X.Cheng, K.D.Wilkinson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 35.00 / 1.99
Space group P 64
Cell size a, b, c (Å), α, β, γ (°) 68.074, 68.074, 225.345, 90.00, 90.00, 120.00
R / Rfree (%) 22.9 / 26.8

Other elements in 2g45:

The structure of Co-Crystal Structure of Znf Ubp Domain From the Deubiquitinating Enzyme Isopeptidase T (Isot) in Complex with Ubiquitin also contains other interesting chemical elements:

Chlorine (Cl) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Co-Crystal Structure of Znf Ubp Domain From the Deubiquitinating Enzyme Isopeptidase T (Isot) in Complex with Ubiquitin (pdb code 2g45). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Co-Crystal Structure of Znf Ubp Domain From the Deubiquitinating Enzyme Isopeptidase T (Isot) in Complex with Ubiquitin, PDB code: 2g45:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 2g45

Go back to Zinc Binding Sites List in 2g45
Zinc binding site 1 out of 2 in the Co-Crystal Structure of Znf Ubp Domain From the Deubiquitinating Enzyme Isopeptidase T (Isot) in Complex with Ubiquitin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Co-Crystal Structure of Znf Ubp Domain From the Deubiquitinating Enzyme Isopeptidase T (Isot) in Complex with Ubiquitin within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn401

b:30.2
occ:1.00
ND1 A:HIS232 2.0 28.0 1.0
SG A:CYS202 2.3 31.3 1.0
SG A:CYS219 2.3 28.9 1.0
SG A:CYS199 2.4 29.9 1.0
CE1 A:HIS232 2.9 29.2 1.0
CG A:HIS232 3.1 29.1 1.0
CB A:CYS199 3.2 29.2 1.0
CB A:CYS219 3.3 25.5 1.0
CB A:CYS202 3.4 32.6 1.0
CB A:HIS232 3.5 26.8 1.0
N A:CYS202 3.8 35.4 1.0
N A:CYS219 3.9 26.4 1.0
CB A:ASN230 4.0 28.1 1.0
NE2 A:HIS232 4.0 29.4 1.0
CA A:CYS202 4.1 35.0 1.0
CD2 A:HIS232 4.2 27.7 1.0
CA A:CYS219 4.2 24.9 1.0
C A:LYS201 4.2 37.3 1.0
CB A:LYS201 4.5 38.9 1.0
OD1 A:ASN230 4.6 28.9 1.0
CA A:LYS201 4.7 37.8 1.0
N A:HIS232 4.7 26.1 1.0
CA A:CYS199 4.7 31.1 1.0
N A:LYS201 4.7 37.5 1.0
CA A:HIS232 4.8 26.4 1.0
CG A:ASN230 4.8 27.2 1.0
C A:CYS202 4.8 35.1 1.0
O A:LYS201 4.8 39.1 1.0
CA A:ASN230 4.9 27.2 1.0
C A:ASN230 5.0 26.8 1.0
O A:ASN230 5.0 26.3 1.0

Zinc binding site 2 out of 2 in 2g45

Go back to Zinc Binding Sites List in 2g45
Zinc binding site 2 out of 2 in the Co-Crystal Structure of Znf Ubp Domain From the Deubiquitinating Enzyme Isopeptidase T (Isot) in Complex with Ubiquitin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Co-Crystal Structure of Znf Ubp Domain From the Deubiquitinating Enzyme Isopeptidase T (Isot) in Complex with Ubiquitin within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn402

b:29.9
occ:1.00
ND1 D:HIS232 2.0 28.2 1.0
SG D:CYS199 2.4 29.6 1.0
SG D:CYS219 2.4 30.2 1.0
SG D:CYS202 2.4 30.1 1.0
CE1 D:HIS232 2.9 29.3 1.0
CG D:HIS232 3.1 28.8 1.0
CB D:CYS199 3.2 29.1 1.0
CB D:CYS202 3.3 32.9 1.0
CB D:CYS219 3.4 26.7 1.0
CB D:HIS232 3.6 25.4 1.0
N D:CYS202 3.8 35.4 1.0
N D:CYS219 3.9 26.8 1.0
CB D:ASN230 4.0 27.1 1.0
NE2 D:HIS232 4.0 29.0 1.0
CA D:CYS202 4.1 35.1 1.0
CD2 D:HIS232 4.2 27.6 1.0
C D:LYS201 4.2 36.7 1.0
CA D:CYS219 4.3 25.3 1.0
CB D:LYS201 4.5 37.2 1.0
O D:LYS201 4.6 38.4 1.0
CA D:CYS199 4.7 31.9 1.0
CA D:LYS201 4.7 37.1 1.0
OD1 D:ASN230 4.7 28.7 1.0
N D:HIS232 4.7 26.0 1.0
N D:LYS201 4.7 37.2 1.0
CA D:HIS232 4.8 25.1 1.0
C D:CYS202 4.8 35.4 1.0
CG D:ASN230 4.9 26.0 1.0
CA D:ASN230 4.9 27.1 1.0
O D:ASN230 5.0 27.1 1.0
C D:ASN230 5.0 27.1 1.0

Reference:

F.E.Reyes-Turcu, J.R.Horton, J.E.Mullally, A.Heroux, X.Cheng, K.D.Wilkinson. The Ubiquitin Binding Domain Znf Ubp Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin. Cell(Cambridge,Mass.) V. 124 1197 2006.
ISSN: ISSN 0092-8674
PubMed: 16564012
DOI: 10.1016/J.CELL.2006.02.038
Page generated: Thu Oct 17 00:01:07 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy