Zinc in PDB 2eli: Solution Structure of the Second Phorbol Esters/Diacylglycerol Binding Domain of Human Protein Kinase C Alpha Type

All present enzymatic activity of Solution Structure of the Second Phorbol Esters/Diacylglycerol Binding Domain of Human Protein Kinase C Alpha Type:
2.7.11.13;

The binding sites of Zinc atom in the Solution Structure of the Second Phorbol Esters/Diacylglycerol Binding Domain of Human Protein Kinase C Alpha Type (pdb code 2eli). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Solution Structure of the Second Phorbol Esters/Diacylglycerol Binding Domain of Human Protein Kinase C Alpha Type, PDB code: 2eli:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Solution Structure of the Second Phorbol Esters/Diacylglycerol Binding Domain of Human Protein Kinase C Alpha Type


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Solution Structure of the Second Phorbol Esters/Diacylglycerol Binding Domain of Human Protein Kinase C Alpha Type within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:0.0 occ:1.00 ND1 A:HIS18 2.1 0.0 1.0 SG A:CYS67 2.2 0.0 1.0 SG A:CYS51 2.3 0.0 1.0 SG A:CYS48 2.3 0.0 1.0 HE1 A:HIS18 2.6 0.0 1.0 CE1 A:HIS18 2.6 0.0 1.0 HG22 A:THR50 2.9 0.0 1.0 HB2 A:CYS48 3.2 0.0 1.0 CB A:CYS48 3.3 0.0 1.0 CG A:HIS18 3.3 0.0 1.0 H A:CYS51 3.3 0.0 1.0 HA A:HIS18 3.4 0.0 1.0 HB3 A:CYS51 3.4 0.0 1.0 HB2 A:CYS67 3.4 0.0 1.0 HB3 A:CYS48 3.5 0.0 1.0 HG23 A:THR50 3.5 0.0 1.0 CB A:CYS51 3.5 0.0 1.0 CB A:CYS67 3.5 0.0 1.0 CG2 A:THR50 3.6 0.0 1.0 H A:LYS19 3.7 0.0 1.0 HG21 A:THR50 3.7 0.0 1.0 NE2 A:HIS18 3.8 0.0 1.0 HB3 A:HIS18 3.9 0.0 1.0 CB A:HIS18 4.0 0.0 1.0 HE1 A:PHE20 4.0 0.0 1.0 N A:CYS51 4.1 0.0 1.0 CA A:HIS18 4.2 0.0 1.0 CD2 A:HIS18 4.2 0.0 1.0 CE1 A:PHE20 4.2 0.0 1.0 HB3 A:CYS67 4.2 0.0 1.0 HZ A:PHE20 4.2 0.0 1.0 HA A:CYS67 4.3 0.0 1.0 CZ A:PHE20 4.3 0.0 1.0 HB2 A:CYS51 4.3 0.0 1.0 CA A:CYS51 4.4 0.0 1.0 H A:THR50 4.4 0.0 1.0 N A:LYS19 4.5 0.0 1.0 CA A:CYS67 4.5 0.0 1.0 HB2 A:MET53 4.6 0.0 1.0 HE2 A:HIS18 4.6 0.0 1.0 H A:MET53 4.6 0.0 1.0 CA A:CYS48 4.7 0.0 1.0 H A:GLY68 4.8 0.0 1.0 HB3 A:MET53 4.8 0.0 1.0 CD1 A:PHE20 4.9 0.0 1.0 C A:HIS18 4.9 0.0 1.0 HA A:CYS48 4.9 0.0 1.0 H A:ASP49 5.0 0.0 1.0 CB A:THR50 5.0 0.0 1.0 H A:ASP52 5.0 0.0 1.0

Zinc binding site 2 out of 2 in the Solution Structure of the Second Phorbol Esters/Diacylglycerol Binding Domain of Human Protein Kinase C Alpha Type


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Solution Structure of the Second Phorbol Esters/Diacylglycerol Binding Domain of Human Protein Kinase C Alpha Type within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:0.0 occ:1.00 ND1 A:HIS56 2.1 0.0 1.0 SG A:CYS59 2.2 0.0 1.0 SG A:CYS34 2.4 0.0 1.0 SG A:CYS31 2.4 0.0 1.0 H A:CYS34 2.9 0.0 1.0 HB2 A:HIS56 2.9 0.0 1.0 CE1 A:HIS56 3.0 0.0 1.0 H A:HIS56 3.0 0.0 1.0 CG A:HIS56 3.1 0.0 1.0 HE1 A:HIS56 3.2 0.0 1.0 HB2 A:CYS31 3.2 0.0 1.0 CB A:CYS31 3.2 0.0 1.0 HB2 A:CYS59 3.3 0.0 1.0 HB3 A:CYS31 3.3 0.0 1.0 CB A:CYS59 3.3 0.0 1.0 HB3 A:CYS34 3.4 0.0 1.0 HB3 A:HIS33 3.4 0.0 1.0 CB A:CYS34 3.5 0.0 1.0 CB A:HIS56 3.5 0.0 1.0 HB3 A:CYS59 3.6 0.0 1.0 N A:CYS34 3.7 0.0 1.0 H A:GLY35 3.8 0.0 1.0 N A:HIS56 3.9 0.0 1.0 NE2 A:HIS56 4.1 0.0 1.0 CA A:CYS34 4.2 0.0 1.0 CD2 A:HIS56 4.2 0.0 1.0 H A:HIS33 4.3 0.0 1.0 HD2 A:HIS33 4.3 0.0 1.0 HB2 A:CYS34 4.4 0.0 1.0 HB3 A:HIS56 4.4 0.0 1.0 CA A:HIS56 4.4 0.0 1.0 CB A:HIS33 4.4 0.0 1.0 HD21 A:LEU38 4.5 0.0 1.0 HA A:VAL55 4.5 0.0 1.0 N A:GLY35 4.6 0.0 1.0 HB A:VAL55 4.6 0.0 1.0 H A:SER36 4.6 0.0 1.0 HB2 A:SER36 4.7 0.0 1.0 CA A:CYS59 4.7 0.0 1.0 CA A:CYS31 4.7 0.0 1.0 C A:HIS33 4.8 0.0 1.0 HA A:CYS59 4.9 0.0 1.0 C A:CYS34 4.9 0.0 1.0 N A:HIS33 4.9 0.0 1.0 H A:ASP32 5.0 0.0 1.0 H A:CYS59 5.0 0.0 1.0 HA A:CYS31 5.0 0.0 1.0 CD2 A:HIS33 5.0 0.0 1.0

N.Tochio, S.Koshiba, K.Saito, T.Tomizawa, S.Watanabe, T.Harada, T.Kigawa, S.Yokoyama. Solution Structure of the Second Phorbol Esters/Diacylglycerol Binding Domain of Human Protein Kinase C Alpha Type To Be Published.