Zinc in PDB 2eih: Crystal Structure of Nad-Dependent Alcohol Dehydrogenase

The structure of Crystal Structure of Nad-Dependent Alcohol Dehydrogenase, PDB code: 2eih was solved by N.Kamiya, T.Hikima, T.Matsu, N.Maoka, Riken Structuralgenomics/Proteomics Initiative (Rsgi), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.69 / 2.30
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	75.580, 133.890, 75.670, 90.00, 107.29, 90.00
R / Rfree (%)	21 / 26.7

The binding sites of Zinc atom in the Crystal Structure of Nad-Dependent Alcohol Dehydrogenase (pdb code 2eih). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Nad-Dependent Alcohol Dehydrogenase, PDB code: 2eih:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Nad-Dependent Alcohol Dehydrogenase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Nad-Dependent Alcohol Dehydrogenase within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn500 b:43.8 occ:1.00 SG A:CYS99 2.4 40.0 1.0 SG A:CYS93 2.5 51.6 1.0 SG A:CYS96 2.6 46.2 1.0 SG A:CYS107 2.6 38.9 1.0 CB A:CYS107 3.3 41.2 1.0 CB A:CYS99 3.4 40.7 1.0 CB A:CYS96 3.4 48.4 1.0 N A:CYS93 3.6 47.6 1.0 CB A:CYS93 3.8 50.7 1.0 N A:GLY94 3.8 51.3 1.0 N A:CYS96 3.8 52.2 1.0 CA A:CYS93 4.0 50.1 1.0 CA A:CYS96 4.2 49.8 1.0 C A:CYS93 4.3 50.9 1.0 N A:CYS99 4.3 39.8 1.0 N A:ARG95 4.3 55.5 1.0 CA A:CYS107 4.3 42.3 1.0 CB A:SER92 4.3 41.6 1.0 CA A:CYS99 4.4 40.3 1.0 CD A:PRO108 4.5 44.1 1.0 CA A:GLY94 4.6 53.3 1.0 C A:SER92 4.7 45.5 1.0 C A:CYS96 4.8 48.1 1.0 O A:CYS96 4.8 48.9 1.0 CA A:SER92 4.9 43.3 1.0 C A:ARG95 4.9 54.4 1.0 C A:GLY94 5.0 54.4 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Nad-Dependent Alcohol Dehydrogenase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Nad-Dependent Alcohol Dehydrogenase within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn501 b:43.8 occ:1.00 SG B:CYS107 2.4 36.6 1.0 SG B:CYS96 2.5 45.9 1.0 SG B:CYS99 2.5 37.0 1.0 SG B:CYS93 2.5 44.0 1.0 CB B:CYS96 3.2 43.9 1.0 CB B:CYS107 3.3 37.6 1.0 CB B:CYS99 3.6 34.5 1.0 CB B:CYS93 3.6 40.6 1.0 N B:CYS96 3.7 46.5 1.0 N B:CYS93 3.7 37.4 1.0 N B:GLY94 3.7 43.5 1.0 CA B:CYS96 4.0 44.6 1.0 CA B:CYS93 4.0 40.3 1.0 N B:ARG95 4.2 47.2 1.0 CA B:CYS107 4.3 40.7 1.0 C B:CYS93 4.3 42.0 1.0 N B:CYS99 4.3 34.7 1.0 CD B:PRO108 4.5 46.4 1.0 CA B:CYS99 4.5 34.8 1.0 CB B:SER92 4.6 34.9 1.0 CA B:GLY94 4.6 45.9 1.0 C B:CYS96 4.7 44.2 1.0 O B:CYS96 4.7 44.1 1.0 C B:SER92 4.7 37.4 1.0 C B:ARG95 4.8 47.8 1.0 C B:GLY94 4.9 46.6 1.0

N.Kamiya, T.Hikima, T.Matsu, N.Maoka. Crystal Structure Analysis of Putative Nad-Dependent Alcohol Dehydrogenase From Thermus Thermophilus HB8 To Be Published.