Atomistry » Zinc » PDB 1my0-1ndv » 1n94
Atomistry »
  Zinc »
    PDB 1my0-1ndv »
      1n94 »

Zinc in PDB 1n94: Aryl Tetrahydropyridine Inhbitors of Farnesyltransferase: Glycine, Phenylalanine and Histidine Derivates

Protein crystallography data

The structure of Aryl Tetrahydropyridine Inhbitors of Farnesyltransferase: Glycine, Phenylalanine and Histidine Derivates, PDB code: 1n94 was solved by S.L.Gwaltney Ii, S.J.O'connor, L.T.Nelson, G.M.Sullivan, H.Imade, W.Wang, L.Hasvold, Q.Li, J.Cohen, W.Z.Gu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 33.94 / 3.50
Space group P 61
Cell size a, b, c (Å), α, β, γ (°) 172.106, 172.106, 69.404, 90.00, 90.00, 120.00
R / Rfree (%) 29.5 / 29.6

Zinc Binding Sites:

The binding sites of Zinc atom in the Aryl Tetrahydropyridine Inhbitors of Farnesyltransferase: Glycine, Phenylalanine and Histidine Derivates (pdb code 1n94). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Aryl Tetrahydropyridine Inhbitors of Farnesyltransferase: Glycine, Phenylalanine and Histidine Derivates, PDB code: 1n94:

Zinc binding site 1 out of 1 in 1n94

Go back to Zinc Binding Sites List in 1n94
Zinc binding site 1 out of 1 in the Aryl Tetrahydropyridine Inhbitors of Farnesyltransferase: Glycine, Phenylalanine and Histidine Derivates


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Aryl Tetrahydropyridine Inhbitors of Farnesyltransferase: Glycine, Phenylalanine and Histidine Derivates within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn2

b:15.0
occ:1.00
OD1 B:ASP297 2.4 50.0 1.0
SG B:CYS299 2.6 28.0 1.0
OD2 B:ASP297 2.8 50.0 1.0
NE2 B:HIS362 2.9 29.1 1.0
CG B:ASP297 2.9 50.0 1.0
CE1 B:HIS362 3.4 29.1 1.0
CB B:CYS299 3.5 28.0 1.0
CD2 B:HIS362 3.7 29.1 1.0
CE2 B:TYR361 3.8 17.9 1.0
OD2 B:ASP352 4.2 59.2 1.0
N B:CYS299 4.3 16.0 1.0
ND1 B:HIS362 4.3 29.1 1.0
CB B:ASP297 4.4 50.0 1.0
CA B:CYS299 4.5 16.0 1.0
CG B:HIS362 4.5 29.1 1.0
CD2 B:TYR361 4.6 17.9 1.0
OH B:TYR361 4.6 17.9 1.0
CZ B:TYR361 4.7 17.9 1.0
CG B:ASP352 4.8 59.2 1.0

Reference:

S.L.Gwaltney Ii, S.J.O'connor, L.T.Nelson, G.M.Sullivan, H.Imade, W.Wang, L.Hasvold, Q.Li, J.Cohen, W.Z.Gu, S.K.Tahir, J.Bauch, K.Marsh, S.C.Ng, D.J.Frost, H.Zhang, S.Muchmore, C.G.Jakob, V.Stoll, C.Hutchins, S.H.Rosenberg, H.L.Sham. Aryl Tetrahydropyridine Inhibitors of Farnesyltransferase: Glycine, Phenylalanine and Histidine Derivatives. Bioorg.Med.Chem.Lett. V. 13 1359 2003.
ISSN: ISSN 0960-894X
PubMed: 12657282
DOI: 10.1016/S0960-894X(03)00095-7
Page generated: Mon Jan 25 16:10:17 2021

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy