Zinc in PDB 1i7w: Beta-Catenin/Phosphorylated E-Cadherin Complex

The structure of Beta-Catenin/Phosphorylated E-Cadherin Complex, PDB code: 1i7w was solved by A.H.Huber, W.I.Weis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	100.00 / 2.00
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	168.600, 85.300, 115.100, 90.00, 107.90, 90.00
R / Rfree (%)	20.6 / 24.5

The structure of Beta-Catenin/Phosphorylated E-Cadherin Complex also contains other interesting chemical elements:

Chlorine

(Cl)

8 atoms

The binding sites of Zinc atom in the Beta-Catenin/Phosphorylated E-Cadherin Complex (pdb code 1i7w). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Beta-Catenin/Phosphorylated E-Cadherin Complex, PDB code: 1i7w:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Beta-Catenin/Phosphorylated E-Cadherin Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Beta-Catenin/Phosphorylated E-Cadherin Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1 b:61.7 occ:0.30 SG A:CYS213 2.1 60.5 1.0 ND1 A:HIS176 2.2 64.4 1.0 CE1 A:HIS176 3.1 62.8 1.0 O A:HOH905 3.1 71.2 1.0 CG A:HIS176 3.2 63.4 1.0 CB A:CYS213 3.2 56.8 1.0 CA A:CYS213 3.6 54.6 1.0 CB A:HIS176 3.6 61.8 1.0 N A:CYS213 4.2 54.9 1.0 NE2 A:HIS176 4.2 61.7 1.0 CD2 A:HIS176 4.3 61.7 1.0 O A:GLU209 4.8 56.6 1.0 CA A:VAL173 4.8 60.0 1.0 C A:CYS213 4.8 50.9 1.0 O A:VAL173 4.9 60.5 1.0 C A:ARG212 5.0 54.9 1.0

Zinc binding site 2 out of 2 in the Beta-Catenin/Phosphorylated E-Cadherin Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Beta-Catenin/Phosphorylated E-Cadherin Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn2 b:61.7 occ:0.40 SG C:CYS213 2.1 52.2 1.0 ND1 C:HIS176 2.2 57.4 1.0 CB C:CYS213 3.1 44.0 1.0 NH2 C:ARG212 3.1 65.3 1.0 O C:HOH995 3.2 64.6 1.0 CG C:HIS176 3.2 53.1 1.0 CE1 C:HIS176 3.2 57.9 1.0 CB C:HIS176 3.5 48.8 1.0 CA C:CYS213 3.5 41.1 1.0 NH1 C:ARG212 3.6 67.8 1.0 CZ C:ARG212 3.7 66.0 1.0 NE2 C:HIS176 4.3 56.4 1.0 N C:CYS213 4.3 38.7 1.0 CD2 C:HIS176 4.3 54.6 1.0 C C:CYS213 4.7 39.7 1.0 CA C:VAL173 4.7 44.2 1.0 O C:VAL173 4.8 44.2 1.0 NE C:ARG212 4.9 62.1 1.0 O C:CYS213 4.9 39.8 1.0 CA C:HIS176 5.0 45.9 1.0 O C:GLU209 5.0 45.4 1.0

A.H.Huber, W.I.Weis. The Structure of the Beta-Catenin/E-Cadherin Complex and the Molecular Basis of Diverse Ligand Recognition By Beta-Catenin. Cell(Cambridge,Mass.) V. 105 391 2001.
ISSN: ISSN 0092-8674
PubMed: 11348595
DOI: 10.1016/S0092-8674(01)00330-0