Atomistry » Zinc » PDB 4efx-4eyn » 4epk
Atomistry »
  Zinc »
    PDB 4efx-4eyn »
      4epk »

Zinc in PDB 4epk: Evidence For A Dual Role of An Active Site Histidine in Alpha-Amino- Beta-Carboxymuconate-Epsilon-Semialdehyde Decarboxylase

Protein crystallography data

The structure of Evidence For A Dual Role of An Active Site Histidine in Alpha-Amino- Beta-Carboxymuconate-Epsilon-Semialdehyde Decarboxylase, PDB code: 4epk was solved by L.Huo, A.J.Fielding, Y.Chen, T.Li, H.Iwaki, J.P.Hosler, L.Chen, Y.Hasegawa, L.Que Jr., A.Liu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 32.35 / 2.60
Space group P 42 21 2
Cell size a, b, c (Å), α, β, γ (°) 91.504, 91.504, 170.123, 90.00, 90.00, 90.00
R / Rfree (%) 20.8 / 28.1

Other elements in 4epk:

The structure of Evidence For A Dual Role of An Active Site Histidine in Alpha-Amino- Beta-Carboxymuconate-Epsilon-Semialdehyde Decarboxylase also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Evidence For A Dual Role of An Active Site Histidine in Alpha-Amino- Beta-Carboxymuconate-Epsilon-Semialdehyde Decarboxylase (pdb code 4epk). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Evidence For A Dual Role of An Active Site Histidine in Alpha-Amino- Beta-Carboxymuconate-Epsilon-Semialdehyde Decarboxylase, PDB code: 4epk:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 4epk

Go back to Zinc Binding Sites List in 4epk
Zinc binding site 1 out of 2 in the Evidence For A Dual Role of An Active Site Histidine in Alpha-Amino- Beta-Carboxymuconate-Epsilon-Semialdehyde Decarboxylase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Evidence For A Dual Role of An Active Site Histidine in Alpha-Amino- Beta-Carboxymuconate-Epsilon-Semialdehyde Decarboxylase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn401

b:49.3
occ:1.00
NE2 A:HIS11 2.2 44.7 1.0
NE2 A:HIS9 2.3 48.7 1.0
NE2 A:HIS177 2.3 46.1 1.0
OD1 A:ASP294 2.9 58.5 1.0
OD2 A:ASP294 3.0 68.6 1.0
CD2 A:HIS11 3.1 49.0 1.0
CG A:ASP294 3.1 65.1 1.0
CD2 A:HIS177 3.2 44.5 1.0
CE1 A:HIS11 3.2 48.7 1.0
CE1 A:HIS9 3.3 50.2 1.0
CD2 A:HIS9 3.3 48.2 1.0
CE1 A:HIS177 3.4 37.7 1.0
CB A:ASP294 4.3 57.0 1.0
CG A:HIS11 4.3 44.8 1.0
ND1 A:HIS11 4.3 49.7 1.0
ND1 A:HIS9 4.4 59.0 1.0
CG A:HIS177 4.4 43.2 1.0
CG A:HIS9 4.4 57.8 1.0
ND1 A:HIS177 4.4 45.2 1.0
CA A:ASP294 4.6 52.4 1.0

Zinc binding site 2 out of 2 in 4epk

Go back to Zinc Binding Sites List in 4epk
Zinc binding site 2 out of 2 in the Evidence For A Dual Role of An Active Site Histidine in Alpha-Amino- Beta-Carboxymuconate-Epsilon-Semialdehyde Decarboxylase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Evidence For A Dual Role of An Active Site Histidine in Alpha-Amino- Beta-Carboxymuconate-Epsilon-Semialdehyde Decarboxylase within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn401

b:64.0
occ:1.00
NE2 B:HIS177 2.3 63.8 1.0
NE2 B:HIS11 2.3 54.2 1.0
NE2 B:HIS9 2.4 60.1 1.0
OD2 B:ASP294 2.5 72.0 1.0
CD2 B:HIS177 3.1 65.3 1.0
CE1 B:HIS9 3.2 62.8 1.0
CG B:ASP294 3.2 65.3 1.0
CE1 B:HIS11 3.2 67.3 1.0
CD2 B:HIS11 3.2 66.1 1.0
CE1 B:HIS177 3.3 72.1 1.0
OD1 B:ASP294 3.5 73.7 1.0
CD2 B:HIS9 3.5 57.3 1.0
CG B:HIS177 4.3 70.7 1.0
ND1 B:HIS11 4.3 69.7 1.0
ND1 B:HIS9 4.3 62.3 1.0
ND1 B:HIS177 4.4 73.7 1.0
CG B:HIS11 4.4 67.0 1.0
CB B:ASP294 4.4 61.6 1.0
CG B:HIS9 4.5 62.6 1.0
CA B:ASP294 4.8 61.6 1.0
CE1 B:PHE297 4.8 74.2 1.0
CD1 B:PHE297 5.0 76.9 1.0

Reference:

L.Huo, A.J.Fielding, Y.Chen, T.Li, H.Iwaki, J.P.Hosler, L.Chen, Y.Hasegawa, L.Que, A.Liu. Evidence For A Dual Role of An Active Site Histidine in Alpha-Amino-Beta-Carboxymuconate-Epsilon-Semialdehyde Decarboxylase Biochemistry V. 51 5811 2012.
ISSN: ISSN 0006-2960
PubMed: 22746257
DOI: 10.1021/BI300635B
Page generated: Sat Oct 26 22:02:53 2024

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy