Zinc in PDB 8wtb: Crystal Structure of Mcsa/Mcsb Complex Truncated By Chymotrypsin

The structure of Crystal Structure of Mcsa/Mcsb Complex Truncated By Chymotrypsin, PDB code: 8wtb was solved by M.Arifuzzaman, E.Kwon, D.Y.Kim, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	88.63 / 2.90
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	179.869, 75.59, 79.19, 90, 99.78, 90
R / Rfree (%)	20.5 / 25.9

The binding sites of Zinc atom in the Crystal Structure of Mcsa/Mcsb Complex Truncated By Chymotrypsin (pdb code 8wtb). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Mcsa/Mcsb Complex Truncated By Chymotrypsin, PDB code: 8wtb:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Mcsa/Mcsb Complex Truncated By Chymotrypsin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Mcsa/Mcsb Complex Truncated By Chymotrypsin within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:49.3 occ:1.00 SG B:CYS102 2.3 45.0 1.0 SG B:CYS84 2.3 54.4 1.0 SG B:CYS81 2.3 52.5 1.0 SG B:CYS99 2.4 56.0 1.0 CB B:CYS81 3.1 62.9 1.0 N B:CYS99 3.4 47.5 1.0 N B:CYS102 3.4 52.6 1.0 CB B:CYS84 3.4 52.5 1.0 CB B:CYS99 3.4 50.6 1.0 CB B:CYS102 3.6 41.9 1.0 N B:CYS84 3.8 54.9 1.0 CA B:CYS99 3.8 51.2 1.0 CA B:CYS102 3.8 49.8 1.0 CA B:CYS84 4.1 50.9 1.0 C B:GLY98 4.1 50.0 1.0 C B:CYS99 4.2 52.8 1.0 O B:CYS99 4.2 50.8 1.0 CA B:GLY98 4.4 56.8 1.0 C B:GLU101 4.4 50.1 1.0 CA B:CYS81 4.6 60.4 1.0 N B:GLY98 4.6 52.7 1.0 N B:GLU101 4.6 55.7 1.0 C B:CYS84 4.6 58.1 1.0 CB B:LYS83 4.8 59.1 1.0 C B:LYS83 4.8 61.0 1.0 N B:GLY85 4.8 55.5 1.0 CB B:GLU101 4.8 48.7 1.0 CA B:GLU101 4.8 48.7 1.0 CB B:MET86 4.9 55.0 1.0 N B:MET86 5.0 52.5 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Mcsa/Mcsb Complex Truncated By Chymotrypsin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Mcsa/Mcsb Complex Truncated By Chymotrypsin within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn201 b:51.9 occ:1.00 SG D:CYS102 2.3 41.3 1.0 SG D:CYS81 2.3 52.8 1.0 SG D:CYS84 2.3 67.8 1.0 CB D:CYS84 2.3 57.6 1.0 SG D:CYS99 2.4 56.9 1.0 CB D:CYS81 3.2 59.7 1.0 CA D:CYS84 3.5 57.1 1.0 N D:CYS102 3.5 59.5 1.0 N D:CYS84 3.6 63.8 1.0 CB D:CYS99 3.6 53.5 1.0 CB D:CYS102 3.7 46.2 1.0 N D:CYS99 3.7 51.9 1.0 C D:GLY98 3.9 45.5 1.0 CA D:CYS102 3.9 53.7 1.0 O D:CYS99 4.1 49.8 1.0 CA D:CYS99 4.1 54.2 1.0 CA D:GLY98 4.1 41.3 1.0 CB D:GLU101 4.3 60.4 1.0 C D:CYS99 4.4 53.9 1.0 O D:GLY98 4.4 45.2 1.0 C D:GLU101 4.5 58.5 1.0 CG D:LYS83 4.6 61.6 1.0 CA D:CYS81 4.7 58.6 1.0 C D:LYS83 4.7 65.3 1.0 C D:CYS84 4.7 63.8 1.0 N D:GLU101 4.7 56.4 1.0 CA D:GLU101 4.7 57.5 1.0 CB D:MET86 4.9 57.0 1.0

M.Arifuzzaman, E.Kwon, D.Y.Kim. Structural Insights Into the Regulation of Protein-Arginine Kinase Mcsb By Mcsa. Proc.Natl.Acad.Sci.Usa V. 121 12121 2024.
ISSN: ESSN 1091-6490
PubMed: 38625935
DOI: 10.1073/PNAS.2320312121