Zinc in PDB 8wni: Crystal Structure of H. Pylori Isoleucyl-Trna Synthetase (Hpilers) in Complex with Val

All present enzymatic activity of Crystal Structure of H. Pylori Isoleucyl-Trna Synthetase (Hpilers) in Complex with Val:
6.1.1.5;

The structure of Crystal Structure of H. Pylori Isoleucyl-Trna Synthetase (Hpilers) in Complex with Val, PDB code: 8wni was solved by Y.Guo, S.Li, T.Zhang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	51.19 / 1.95
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	52.692, 52.857, 103.041, 92.19, 97.63, 103.82
R / Rfree (%)	16.6 / 19.3

The binding sites of Zinc atom in the Crystal Structure of H. Pylori Isoleucyl-Trna Synthetase (Hpilers) in Complex with Val (pdb code 8wni). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of H. Pylori Isoleucyl-Trna Synthetase (Hpilers) in Complex with Val, PDB code: 8wni:

Zinc binding site 1 out of 1 in the Crystal Structure of H. Pylori Isoleucyl-Trna Synthetase (Hpilers) in Complex with Val


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of H. Pylori Isoleucyl-Trna Synthetase (Hpilers) in Complex with Val within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:20.6 occ:1.00 SG A:CYS895 2.3 23.3 1.0 SG A:CYS913 2.3 20.7 1.0 SG A:CYS898 2.3 21.9 1.0 SG A:CYS910 2.3 23.6 1.0 CB A:CYS895 3.1 23.2 1.0 CB A:CYS913 3.2 20.8 1.0 CB A:CYS898 3.4 24.1 1.0 CB A:CYS910 3.5 25.3 1.0 N A:CYS898 3.7 22.8 1.0 N A:CYS910 3.8 25.9 1.0 NH2 A:ARG912 4.0 20.1 1.0 CA A:CYS898 4.1 24.1 1.0 CA A:CYS910 4.2 24.2 1.0 N A:CYS913 4.2 22.5 1.0 CA A:CYS913 4.3 23.5 1.0 NE A:ARG912 4.5 22.0 1.0 CB A:ARG897 4.6 23.4 1.0 NH2 A:ARG900 4.6 28.3 1.0 CA A:CYS895 4.6 24.4 1.0 C A:ARG897 4.7 24.6 1.0 C A:CYS910 4.8 25.0 1.0 CZ A:ARG912 4.8 22.1 1.0 O A:CYS910 4.8 22.7 1.0 C A:PRO909 4.9 23.2 1.0 N A:ARG897 4.9 24.1 1.0 C A:CYS898 4.9 23.9 1.0 NE A:ARG900 4.9 25.8 1.0 CA A:ARG897 5.0 24.6 1.0

X.Chen, Y.Guo, J.Shi, Y.Wang, X.Guo, G.Wu, S.Li, T.Zhang. Structural Basis For Substrate and Antibiotic Recognition By Helicobacter Pylori Isoleucyl-Trna Synthetase. Febs Lett. 2024.
ISSN: ISSN 0014-5793
PubMed: 38246751
DOI: 10.1002/1873-3468.14805