Zinc in PDB 8we4: Sars-Cov-2 Omicron Xbb.1.5 Rbd Complexed with Human ACE2 and S304

The binding sites of Zinc atom in the Sars-Cov-2 Omicron Xbb.1.5 Rbd Complexed with Human ACE2 and S304 (pdb code 8we4). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Sars-Cov-2 Omicron Xbb.1.5 Rbd Complexed with Human ACE2 and S304, PDB code: 8we4:

Zinc binding site 1 out of 1 in the Sars-Cov-2 Omicron Xbb.1.5 Rbd Complexed with Human ACE2 and S304


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sars-Cov-2 Omicron Xbb.1.5 Rbd Complexed with Human ACE2 and S304 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn905 b:55.7 occ:1.00 OE2 A:GLU402 1.9 60.3 1.0 NE2 A:HIS378 2.0 60.3 1.0 NE2 A:HIS374 2.1 60.3 1.0 CD2 A:HIS374 2.7 60.3 1.0 CD2 A:HIS378 2.8 60.3 1.0 CD A:GLU402 3.0 60.3 1.0 CE1 A:HIS378 3.2 60.3 1.0 CE1 A:HIS374 3.2 60.3 1.0 OE2 A:GLU375 3.4 60.3 1.0 OE1 A:GLU402 3.8 60.3 1.0 CG A:GLU402 3.8 60.3 1.0 CG A:HIS374 3.9 60.3 1.0 CG A:HIS378 4.0 60.3 1.0 ND1 A:HIS374 4.2 60.3 1.0 ND1 A:HIS378 4.2 60.3 1.0 CD A:GLU375 4.4 60.3 1.0 OE1 A:GLU375 4.8 60.3 1.0 CB A:GLU402 4.9 60.3 1.0

W.Li, Z.Xu, T.Niu, Y.Xie, Z.Zhao, D.Li, Q.He, W.Sun, K.Shi, W.Guo, Z.Chang, K.Liu, Z.Fan, J.Qi, G.F.Gao. Key Mechanistic Features of the Trade-Off Between Antibody Escape and Host Cell Binding in the Sars-Cov-2 Omicron Variant Spike Proteins. Embo J. V. 43 1484 2024.
ISSN: ESSN 1460-2075
PubMed: 38467833
DOI: 10.1038/S44318-024-00062-Z