Zinc in PDB 8uqb: Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1)

Enzymatic activity of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1)

All present enzymatic activity of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1):
2.3.2.23; 2.3.2.24; 2.3.2.27;

Protein crystallography data

The structure of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1), PDB code: 8uqb was solved by Q.Hu, M.V.Botuyan, G.Mer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 39.37 / 2.48
Space group P 32 2 1
Cell size a, b, c (Å), α, β, γ (°) 101.948, 101.948, 86.992, 90, 90, 120
R / Rfree (%) 21.8 / 26

Other elements in 8uqb:

The structure of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1) also contains other interesting chemical elements:

Chlorine (Cl) 4 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1) (pdb code 8uqb). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1), PDB code: 8uqb:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 8uqb

Go back to Zinc Binding Sites List in 8uqb
Zinc binding site 1 out of 2 in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn4001

b:50.3
occ:1.00
 ND1 A:HIS33 2.0 44.6 1.0
SG A:CYS51 2.3 45.0 1.0
SG A:CYS31 2.3 48.1 1.0
SG A:CYS54 2.3 47.5 1.0
CE1 A:HIS33 3.0 49.5 1.0
CG A:HIS33 3.0 52.2 1.0
CB A:CYS51 3.1 49.3 1.0
CB A:CYS31 3.2 54.2 1.0
CB A:HIS33 3.4 47.0 1.0
CB A:CYS54 3.6 36.3 1.0
N A:CYS54 3.9 48.7 1.0
NE2 A:HIS33 4.1 44.5 1.0
CD2 A:HIS33 4.1 43.9 1.0
CA A:CYS54 4.4 50.3 1.0
N A:HIS33 4.4 47.4 1.0
CB A:PHE53 4.5 47.2 1.0
CA A:HIS33 4.5 49.9 1.0
CA A:CYS31 4.5 48.1 1.0
CA A:CYS51 4.6 58.6 1.0
O A:CYS31 4.7 45.1 1.0
C A:CYS31 4.7 47.2 1.0
C A:PHE53 4.9 45.0 1.0
CB A:ARG56 5.0 64.9 1.0
C A:CYS54 5.0 47.9 1.0
CD2 A:PHE53 5.0 50.5 1.0
CD1 A:LEU29 5.0 61.1 1.0

Zinc binding site 2 out of 2 in 8uqb

Go back to Zinc Binding Sites List in 8uqb
Zinc binding site 2 out of 2 in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20- Residue Linker (Crystallization Condition 1) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn4002

b:75.4
occ:1.00
 SG A:CYS36 2.3 83.9 1.0
SG A:CYS16 2.3 68.4 1.0
SG A:CYS19 2.3 76.3 1.0
SG A:CYS39 2.3 65.3 1.0
CB A:CYS39 3.3 72.1 1.0
CB A:CYS19 3.4 65.7 1.0
CB A:CYS16 3.6 75.9 1.0
CB A:CYS36 3.7 66.1 1.0
N A:CYS19 3.8 62.2 1.0
N A:CYS36 4.0 64.5 1.0
CA A:CYS19 4.2 69.8 1.0
CB A:ILE18 4.4 53.1 1.0
CA A:CYS36 4.4 68.0 1.0
CA A:CYS39 4.5 71.7 1.0
N A:CYS39 4.5 75.2 1.0
C A:ILE18 4.8 60.9 1.0
N A:ILE18 4.9 61.1 1.0
O A:CYS36 4.9 67.3 1.0
CA A:ILE18 4.9 60.4 1.0
CA A:CYS16 5.0 69.5 1.0

Reference:

Q.Hu, M.V.Botuyan, G.Mer. Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 20-Residue Linker (Crystallization Condition 1) To Be Published.
Page generated: Thu Oct 31 12:27:24 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy