Zinc in PDB 8uks: Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry
Enzymatic activity of Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry
All present enzymatic activity of Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry:
2.7.7.6;
2.7.7.6;
Protein crystallography data
The structure of Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry, PDB code: 8uks
was solved by
P.Hou,
J.Oh,
D.Wang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 47.76 / 3.40 |
| Space group | C 1 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 157.118, 221.626, 189.961, 90, 97.4, 90 |
| R / Rfree (%) | 26.7 / 30.2 |
Other elements in 8uks:
The structure of Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry also contains other interesting chemical elements:
| Magnesium | (Mg) | 2 atoms |
Zinc Binding Sites:
The binding sites of Zinc atom in the Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry
(pdb code 8uks). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 8 binding sites of Zinc where determined in the Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry, PDB code: 8uks:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8;
In total 8 binding sites of Zinc where determined in the Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry, PDB code: 8uks:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8;
Zinc binding site 1 out of 8 in 8uks
Go back to
Zinc Binding Sites List in 8uks
Zinc binding site 1 out
of 8 in the Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry within 5.0Å range:
|
Zinc binding site 2 out of 8 in 8uks
Go back to
Zinc Binding Sites List in 8uks
Zinc binding site 2 out
of 8 in the Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry within 5.0Å range:
|
Zinc binding site 3 out of 8 in 8uks
Go back to
Zinc Binding Sites List in 8uks
Zinc binding site 3 out
of 8 in the Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry within 5.0Å range:
|
Zinc binding site 4 out of 8 in 8uks
Go back to
Zinc Binding Sites List in 8uks
Zinc binding site 4 out
of 8 in the Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry within 5.0Å range:
|
Zinc binding site 5 out of 8 in 8uks
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Zinc Binding Sites List in 8uks
Zinc binding site 5 out
of 8 in the Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry within 5.0Å range:
|
Zinc binding site 6 out of 8 in 8uks
Go back to
Zinc Binding Sites List in 8uks
Zinc binding site 6 out
of 8 in the Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry within 5.0Å range:
|
Zinc binding site 7 out of 8 in 8uks
Go back to
Zinc Binding Sites List in 8uks
Zinc binding site 7 out
of 8 in the Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry within 5.0Å range:
|
Zinc binding site 8 out of 8 in 8uks
Go back to
Zinc Binding Sites List in 8uks
Zinc binding site 8 out
of 8 in the Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of Rna Polymerase II Elongation Complex with Fapy-Dg Lesion Soaking with Ctp Before Chemistry within 5.0Å range:
|
Reference:
S.Gao,
P.Hou,
J.Oh,
D.Wang,
M.M.Greenberg.
Molecular Mechanism of Rna Polymerase II Transcriptional Mutagenesis By the Epimerizable Dna Lesion, Fapy·Dg. J.Am.Chem.Soc. V. 146 6274 2024.
ISSN: ESSN 1520-5126
PubMed: 38393762
DOI: 10.1021/JACS.3C14476
Page generated: Thu Oct 31 12:19:14 2024
ISSN: ESSN 1520-5126
PubMed: 38393762
DOI: 10.1021/JACS.3C14476
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