Zinc in PDB 8uib: Structure of the Human INTS9-INTS11-BRAT1 Complex

The binding sites of Zinc atom in the Structure of the Human INTS9-INTS11-BRAT1 Complex (pdb code 8uib). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of the Human INTS9-INTS11-BRAT1 Complex, PDB code: 8uib:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of the Human INTS9-INTS11-BRAT1 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the Human INTS9-INTS11-BRAT1 Complex within 5.0Å range: probe atom residue distance (Å) B Occ K:Zn801 b:47.4 occ:1.00 OD2 K:ASP178 2.1 34.2 1.0 ND1 K:HIS70 2.3 26.9 1.0 NE2 K:HIS157 2.3 34.8 1.0 NE2 K:HIS68 2.3 26.9 1.0 CE1 K:HIS70 2.7 26.9 1.0 CG K:ASP178 2.7 34.2 1.0 CD2 K:HIS157 2.8 34.8 1.0 CD2 K:HIS68 3.1 26.9 1.0 CB K:ASP178 3.2 34.2 1.0 CE1 K:HIS68 3.3 26.9 1.0 CE1 K:HIS157 3.3 34.8 1.0 NE2 K:HIS392 3.4 38.7 1.0 SG T:CYS820 3.5 33.0 1.0 CG K:HIS70 3.6 26.9 1.0 OD1 K:ASP178 3.7 34.2 1.0 CB T:CYS820 3.7 33.0 1.0 CG K:HIS157 3.9 34.8 1.0 NE2 K:HIS70 4.0 26.9 1.0 CE1 K:HIS392 4.1 38.7 1.0 ND1 K:HIS157 4.1 34.8 1.0 ZN K:ZN802 4.1 39.5 1.0 CG K:HIS68 4.3 26.9 1.0 ND1 K:HIS68 4.3 26.9 1.0 CD2 K:HIS392 4.3 38.7 1.0 CB K:HIS70 4.3 26.9 1.0 CD2 K:HIS70 4.4 26.9 1.0 CA K:ASP178 4.5 34.2 1.0 NE2 K:HIS73 4.8 24.8 1.0 O K:ASP178 5.0 34.2 1.0 CD2 K:HIS73 5.0 24.8 1.0

Zinc binding site 2 out of 2 in the Structure of the Human INTS9-INTS11-BRAT1 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of the Human INTS9-INTS11-BRAT1 Complex within 5.0Å range: probe atom residue distance (Å) B Occ K:Zn802 b:39.5 occ:1.00 OD2 K:ASP72 2.0 25.8 1.0 SG T:CYS820 2.3 33.0 1.0 NE2 K:HIS414 2.3 35.2 1.0 NE2 K:HIS73 2.3 24.8 1.0 CD2 K:HIS73 2.7 24.8 1.0 OD2 K:ASP178 2.8 34.2 1.0 CE1 K:HIS414 2.9 35.2 1.0 CG K:ASP72 2.9 25.8 1.0 OD1 K:ASP72 3.2 25.8 1.0 CD2 K:HIS414 3.4 35.2 1.0 CB T:CYS820 3.5 33.0 1.0 CE1 K:HIS73 3.6 24.8 1.0 CG K:ASP178 3.8 34.2 1.0 ND1 K:HIS414 4.0 35.2 1.0 CG K:HIS73 4.0 24.8 1.0 OD1 K:ASP178 4.1 34.2 1.0 ZN K:ZN801 4.1 47.4 1.0 CG K:HIS414 4.3 35.2 1.0 CB K:ASP72 4.3 25.8 1.0 CA T:CYS820 4.3 33.0 1.0 CE1 K:HIS68 4.4 26.9 1.0 ND1 K:HIS73 4.4 24.8 1.0 CG1 K:VAL15 4.5 35.7 1.0 NE2 K:HIS68 4.5 26.9 1.0 O K:ASP72 4.8 25.8 1.0 OG K:SER18 4.9 27.6 1.0 C K:ASP72 4.9 25.8 1.0 ND1 K:HIS70 5.0 26.9 1.0

M.H.Lin, M.K.Jensen, N.D.Elrod, H.F.Chu, M.Haseley, A.C.Beam, K.L.Huang, W.Chiang, W.K.Russell, K.Williams, C.Proschel, E.J.Wagner, L.Tong. Cytoplasmic Binding Partners of the Integrator Endonuclease INTS11 and Its Paralog CPSF73 Are Required For Their Nuclear Function. Mol.Cell V. 84 2900 2024.
ISSN: ISSN 1097-2765
PubMed: 39032490
DOI: 10.1016/J.MOLCEL.2024.06.017