Zinc in PDB 8tho: Solution Structure of the Zinc Finger Repeat Domain of BCL11A (ZNF456)

The binding sites of Zinc atom in the Solution Structure of the Zinc Finger Repeat Domain of BCL11A (ZNF456) (pdb code 8tho). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Solution Structure of the Zinc Finger Repeat Domain of BCL11A (ZNF456), PDB code: 8tho:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Solution Structure of the Zinc Finger Repeat Domain of BCL11A (ZNF456)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Solution Structure of the Zinc Finger Repeat Domain of BCL11A (ZNF456) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:0.0 occ:1.00 NE2 A:HIS29 2.1 0.0 1.0 NE2 A:HIS25 2.1 0.0 1.0 SG A:CYS12 2.3 0.0 1.0 SG A:CYS9 2.3 0.0 1.0 H A:CYS12 3.0 0.0 1.0 CE1 A:HIS25 3.0 0.0 1.0 CE1 A:HIS29 3.1 0.0 1.0 CD2 A:HIS29 3.1 0.0 1.0 HE1 A:HIS25 3.2 0.0 1.0 CD2 A:HIS25 3.2 0.0 1.0 CB A:CYS9 3.2 0.0 1.0 HB2 A:CYS9 3.2 0.0 1.0 HB2 A:CYS12 3.3 0.0 1.0 HE2 A:LYS14 3.3 0.0 1.0 CB A:CYS12 3.3 0.0 1.0 HE1 A:HIS29 3.4 0.0 1.0 HD2 A:HIS29 3.4 0.0 1.0 HB3 A:CYS9 3.5 0.0 1.0 HD2 A:HIS25 3.5 0.0 1.0 HA A:ARG26 3.5 0.0 1.0 N A:CYS12 3.7 0.0 1.0 HZ1 A:LYS14 3.9 0.0 1.0 HB2 A:TYR11 4.0 0.0 1.0 CA A:CYS12 4.1 0.0 1.0 HZ2 A:LYS14 4.1 0.0 1.0 ND1 A:HIS25 4.2 0.0 1.0 HB2 A:ARG26 4.2 0.0 1.0 CE A:LYS14 4.2 0.0 1.0 ND1 A:HIS29 4.2 0.0 1.0 HB3 A:CYS12 4.3 0.0 1.0 NZ A:LYS14 4.3 0.0 1.0 CG A:HIS25 4.3 0.0 1.0 CG A:HIS29 4.3 0.0 1.0 HG2 A:ARG26 4.4 0.0 1.0 CA A:ARG26 4.4 0.0 1.0 HA A:CYS12 4.5 0.0 1.0 HG2 A:LYS14 4.5 0.0 1.0 HG3 A:ARG26 4.6 0.0 1.0 H A:TYR11 4.6 0.0 1.0 CA A:CYS9 4.7 0.0 1.0 C A:TYR11 4.7 0.0 1.0 CB A:ARG26 4.7 0.0 1.0 N A:ARG26 4.8 0.0 1.0 CG A:ARG26 4.8 0.0 1.0 HE3 A:LYS14 4.9 0.0 1.0 HA A:CYS9 4.9 0.0 1.0 O A:HIS25 5.0 0.0 1.0 CB A:TYR11 5.0 0.0 1.0

Zinc binding site 2 out of 3 in the Solution Structure of the Zinc Finger Repeat Domain of BCL11A (ZNF456)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Solution Structure of the Zinc Finger Repeat Domain of BCL11A (ZNF456) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn202 b:0.0 occ:1.00 NE2 A:HIS57 2.1 0.0 1.0 NE2 A:HIS53 2.2 0.0 1.0 SG A:CYS37 2.3 0.0 1.0 SG A:CYS40 2.3 0.0 1.0 H A:CYS40 2.6 0.0 1.0 CD2 A:HIS57 3.1 0.0 1.0 CE1 A:HIS53 3.1 0.0 1.0 N A:CYS40 3.2 0.0 1.0 CE1 A:HIS57 3.2 0.0 1.0 HB2 A:LEU39 3.2 0.0 1.0 HB2 A:CYS40 3.2 0.0 1.0 CD2 A:HIS53 3.3 0.0 1.0 CB A:CYS40 3.3 0.0 1.0 CB A:CYS37 3.3 0.0 1.0 HE1 A:HIS53 3.3 0.0 1.0 HD2 A:HIS57 3.4 0.0 1.0 HB2 A:CYS37 3.4 0.0 1.0 HE1 A:HIS57 3.4 0.0 1.0 HD2 A:HIS53 3.5 0.0 1.0 HB3 A:CYS37 3.5 0.0 1.0 CA A:CYS40 3.8 0.0 1.0 H A:LEU39 4.0 0.0 1.0 C A:LEU39 4.1 0.0 1.0 HD11 A:LEU39 4.2 0.0 1.0 CB A:LEU39 4.2 0.0 1.0 HB3 A:CYS40 4.2 0.0 1.0 CG A:HIS57 4.3 0.0 1.0 ND1 A:HIS57 4.3 0.0 1.0 ND1 A:HIS53 4.3 0.0 1.0 CG A:HIS53 4.4 0.0 1.0 CA A:LEU39 4.6 0.0 1.0 HA A:CYS40 4.6 0.0 1.0 N A:LEU39 4.7 0.0 1.0 CA A:CYS37 4.7 0.0 1.0 HB3 A:LEU39 4.7 0.0 1.0 HB3 A:TYR42 4.7 0.0 1.0 HD13 A:LEU39 4.8 0.0 1.0 C A:CYS40 4.8 0.0 1.0 O A:CYS40 4.8 0.0 1.0 HA A:CYS37 4.9 0.0 1.0 CD1 A:LEU39 4.9 0.0 1.0

Zinc binding site 3 out of 3 in the Solution Structure of the Zinc Finger Repeat Domain of BCL11A (ZNF456)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Solution Structure of the Zinc Finger Repeat Domain of BCL11A (ZNF456) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn203 b:0.0 occ:1.00 NE2 A:HIS88 2.2 0.0 1.0 NE2 A:HIS83 2.2 0.0 1.0 SG A:CYS70 2.3 0.0 1.0 SG A:CYS67 2.3 0.0 1.0 CE1 A:HIS88 3.0 0.0 1.0 HB2 A:CYS70 3.1 0.0 1.0 HE1 A:HIS88 3.1 0.0 1.0 CE1 A:HIS83 3.2 0.0 1.0 HG13 A:ILE69 3.2 0.0 1.0 HB3 A:CYS67 3.3 0.0 1.0 CD2 A:HIS83 3.3 0.0 1.0 CB A:CYS70 3.3 0.0 1.0 CB A:CYS67 3.3 0.0 1.0 HE1 A:HIS83 3.4 0.0 1.0 CD2 A:HIS88 3.4 0.0 1.0 HD2 A:HIS83 3.5 0.0 1.0 H A:CYS70 3.6 0.0 1.0 HB2 A:CYS67 3.6 0.0 1.0 HD2 A:HIS88 3.8 0.0 1.0 HD12 A:ILE69 3.9 0.0 1.0 N A:CYS70 4.0 0.0 1.0 CG1 A:ILE69 4.1 0.0 1.0 HB3 A:CYS70 4.1 0.0 1.0 HB3 A:MET72 4.1 0.0 1.0 CA A:CYS70 4.2 0.0 1.0 HG12 A:ILE69 4.2 0.0 1.0 ND1 A:HIS88 4.3 0.0 1.0 HD21 A:LEU80 4.3 0.0 1.0 ND1 A:HIS83 4.4 0.0 1.0 HE3 A:TRP87 4.4 0.0 1.0 CG A:HIS83 4.4 0.0 1.0 HA A:CYS70 4.4 0.0 1.0 CG A:HIS88 4.5 0.0 1.0 HA A:MET84 4.5 0.0 1.0 CD1 A:ILE69 4.5 0.0 1.0 HB2 A:MET84 4.5 0.0 1.0 CA A:CYS67 4.7 0.0 1.0 HD13 A:ILE69 4.8 0.0 1.0 HB2 A:MET72 4.9 0.0 1.0 C A:ILE69 4.9 0.0 1.0 H A:MET72 5.0 0.0 1.0

T.Viennet, M.Yin, A.Jayaraj, W.Kim, Z.-Y.J.Sun, H.-S.Seo, S.Dhe-Paganon, S.H.Orkin, H.Arthanari. Structural and Dynamic Investigation of Dna-Binding By BCL11A Reveals A Specific Role For ZNF6 To Be Published.