Zinc in PDB 8t70: Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fptii and Tkcmiim Peptide

The structure of Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fptii and Tkcmiim Peptide, PDB code: 8t70 was solved by Y.Wang, L.S.Beese, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.77 / 1.89
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	140.768, 140.768, 129.503, 90, 90, 90
R / Rfree (%)	18.5 / 21.2

The binding sites of Zinc atom in the Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fptii and Tkcmiim Peptide (pdb code 8t70). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fptii and Tkcmiim Peptide, PDB code: 8t70:

Zinc binding site 1 out of 1 in the Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fptii and Tkcmiim Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fptii and Tkcmiim Peptide within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn601 b:28.8 occ:1.00 OD2 B:ASP323 2.1 31.3 1.0 NE2 B:HIS410 2.3 30.1 1.0 SG B:CYS325 2.3 25.8 1.0 S1 B:BT6606 2.3 36.1 1.0 OD1 B:ASP323 2.6 27.4 1.0 CG B:ASP323 2.6 28.5 1.0 CD2 B:HIS410 3.0 29.9 1.0 CB B:CYS325 3.3 25.2 1.0 CE1 B:HIS410 3.4 30.8 1.0 C1 B:BT6606 3.5 45.5 1.0 C6 B:BT6606 3.7 44.4 1.0 CE2 B:TYR409 3.9 32.7 1.0 CB B:ASP323 4.1 25.7 1.0 N B:CYS325 4.2 26.0 1.0 O B:HOH868 4.2 38.2 1.0 O B:HOH728 4.2 29.8 1.0 CG B:HIS410 4.2 24.8 1.0 CB B:ASP400 4.2 25.9 1.0 CA B:CYS325 4.3 29.6 1.0 ND1 B:HIS410 4.4 29.5 1.0 OH B:TYR409 4.5 28.6 1.0 CG B:ASP400 4.5 29.6 1.0 CZ B:TYR409 4.7 26.3 1.0 CD2 B:TYR409 4.7 30.0 1.0 CA B:ASP400 4.7 28.5 1.0 C2 B:BT6606 4.8 46.3 1.0 OD2 B:ASP400 4.8 31.8 1.0 OD1 B:ASP400 4.9 30.7 1.0

Y.Wang, L.S.Beese. Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fptii and Tkcmiim Peptide To Be Published.