Zinc in PDB 8t3w: Structure of BRE1-Nucleosome Complex - STATE2
Enzymatic activity of Structure of BRE1-Nucleosome Complex - STATE2
All present enzymatic activity of Structure of BRE1-Nucleosome Complex - STATE2:
2.3.2.27;
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of BRE1-Nucleosome Complex - STATE2
(pdb code 8t3w). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the
Structure of BRE1-Nucleosome Complex - STATE2, PDB code: 8t3w:
Jump to Zinc binding site number:
1;
2;
3;
4;
Zinc binding site 1 out
of 4 in 8t3w
Go back to
Zinc Binding Sites List in 8t3w
Zinc binding site 1 out
of 4 in the Structure of BRE1-Nucleosome Complex - STATE2
![](/pictures/ZN/pdb/t3/8t3w-ZN-sphere_01.jpg) Mono view
![](/pictures/ZN/pdb/t3/8t3w-ZN-sphere_01_stereo.jpg) Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Structure of BRE1-Nucleosome Complex - STATE2 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
K:Zn801
b:153.9
occ:1.00
|
ND1
|
K:HIS665
|
2.1
|
138.4
|
1.0
|
SG
|
K:CYS683
|
2.3
|
119.4
|
1.0
|
SG
|
K:CYS663
|
2.3
|
139.7
|
1.0
|
SG
|
K:CYS686
|
2.3
|
125.6
|
1.0
|
CE1
|
K:HIS665
|
2.5
|
138.4
|
1.0
|
CB
|
K:CYS663
|
2.7
|
139.7
|
1.0
|
CB
|
K:CYS686
|
3.1
|
125.6
|
1.0
|
OG1
|
K:THR685
|
3.1
|
124.4
|
1.0
|
CB
|
K:CYS683
|
3.3
|
119.4
|
1.0
|
CG
|
K:HIS665
|
3.3
|
138.4
|
1.0
|
N
|
K:CYS686
|
3.5
|
125.6
|
1.0
|
NE2
|
K:HIS665
|
3.7
|
138.4
|
1.0
|
CA
|
K:CYS686
|
3.8
|
125.6
|
1.0
|
CB
|
K:HIS665
|
4.0
|
138.4
|
1.0
|
CD2
|
K:HIS665
|
4.1
|
138.4
|
1.0
|
CA
|
K:CYS663
|
4.2
|
139.7
|
1.0
|
CB
|
K:THR685
|
4.4
|
124.4
|
1.0
|
C
|
K:CYS686
|
4.5
|
125.6
|
1.0
|
C
|
K:THR685
|
4.6
|
124.4
|
1.0
|
C
|
K:CYS663
|
4.7
|
139.7
|
1.0
|
CA
|
K:CYS683
|
4.7
|
119.4
|
1.0
|
N
|
K:ASN687
|
4.7
|
119.7
|
1.0
|
O
|
K:CYS663
|
4.9
|
139.7
|
1.0
|
N
|
K:THR685
|
4.9
|
124.4
|
1.0
|
CA
|
K:THR685
|
4.9
|
124.4
|
1.0
|
N
|
K:HIS665
|
4.9
|
138.4
|
1.0
|
N
|
K:CYS663
|
5.0
|
139.7
|
1.0
|
|
Zinc binding site 2 out
of 4 in 8t3w
Go back to
Zinc Binding Sites List in 8t3w
Zinc binding site 2 out
of 4 in the Structure of BRE1-Nucleosome Complex - STATE2
![](/pictures/ZN/pdb/t3/8t3w-ZN-sphere_02.jpg) Mono view
![](/pictures/ZN/pdb/t3/8t3w-ZN-sphere_02_stereo.jpg) Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Structure of BRE1-Nucleosome Complex - STATE2 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
K:Zn802
b:174.2
occ:1.00
|
SG
|
K:CYS668
|
2.3
|
143.2
|
1.0
|
SG
|
K:CYS651
|
2.3
|
163.4
|
1.0
|
SG
|
K:CYS671
|
2.3
|
136.3
|
1.0
|
SG
|
K:CYS648
|
2.3
|
162.6
|
1.0
|
CB
|
K:CYS648
|
2.6
|
162.6
|
1.0
|
CB
|
K:CYS651
|
2.8
|
163.4
|
1.0
|
CB
|
K:CYS671
|
3.1
|
136.3
|
1.0
|
CB
|
K:CYS668
|
3.4
|
143.2
|
1.0
|
N
|
K:CYS651
|
3.4
|
163.4
|
1.0
|
CA
|
K:CYS651
|
3.7
|
163.4
|
1.0
|
CA
|
K:CYS648
|
4.0
|
162.6
|
1.0
|
N
|
K:CYS671
|
4.2
|
136.3
|
1.0
|
CA
|
K:CYS671
|
4.2
|
136.3
|
1.0
|
N
|
K:CYS668
|
4.3
|
143.2
|
1.0
|
CA
|
K:CYS668
|
4.4
|
143.2
|
1.0
|
C
|
K:CYS648
|
4.4
|
162.6
|
1.0
|
C
|
K:LEU650
|
4.5
|
157.7
|
1.0
|
O
|
K:CYS648
|
4.5
|
162.6
|
1.0
|
CB
|
K:LEU650
|
4.5
|
157.7
|
1.0
|
C
|
K:CYS651
|
4.7
|
163.4
|
1.0
|
N
|
K:CYS648
|
4.8
|
162.6
|
1.0
|
N
|
K:SER652
|
4.8
|
164.7
|
1.0
|
N
|
K:LEU650
|
4.8
|
157.7
|
1.0
|
CA
|
K:LEU650
|
4.9
|
157.7
|
1.0
|
O
|
K:CYS668
|
4.9
|
143.2
|
1.0
|
C
|
K:CYS668
|
4.9
|
143.2
|
1.0
|
|
Zinc binding site 3 out
of 4 in 8t3w
Go back to
Zinc Binding Sites List in 8t3w
Zinc binding site 3 out
of 4 in the Structure of BRE1-Nucleosome Complex - STATE2
![](/pictures/ZN/pdb/t3/8t3w-ZN-sphere_03.jpg) Mono view
![](/pictures/ZN/pdb/t3/8t3w-ZN-sphere_03_stereo.jpg) Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Structure of BRE1-Nucleosome Complex - STATE2 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
L:Zn801
b:208.9
occ:1.00
|
CE1
|
L:HIS665
|
1.9
|
173.8
|
1.0
|
ND1
|
L:HIS665
|
2.3
|
173.8
|
1.0
|
SG
|
L:CYS663
|
2.3
|
172.8
|
1.0
|
OG1
|
L:THR685
|
2.9
|
182.4
|
1.0
|
SG
|
L:CYS683
|
2.9
|
186.2
|
1.0
|
SG
|
L:CYS686
|
2.9
|
190.4
|
1.0
|
NE2
|
L:HIS665
|
3.1
|
173.8
|
1.0
|
CB
|
L:CYS686
|
3.1
|
190.4
|
1.0
|
CB
|
L:CYS663
|
3.3
|
172.8
|
1.0
|
N
|
L:CYS686
|
3.4
|
190.4
|
1.0
|
CG
|
L:HIS665
|
3.5
|
173.8
|
1.0
|
CB
|
L:CYS683
|
3.8
|
186.2
|
1.0
|
CA
|
L:CYS686
|
3.8
|
190.4
|
1.0
|
CD2
|
L:HIS665
|
3.9
|
173.8
|
1.0
|
CB
|
L:THR685
|
4.2
|
182.4
|
1.0
|
C
|
L:CYS686
|
4.5
|
190.4
|
1.0
|
C
|
L:THR685
|
4.5
|
182.4
|
1.0
|
N
|
L:ASN687
|
4.5
|
188.6
|
1.0
|
CB
|
L:HIS665
|
4.6
|
173.8
|
1.0
|
CA
|
L:CYS663
|
4.7
|
172.8
|
1.0
|
CA
|
L:THR685
|
4.7
|
182.4
|
1.0
|
N
|
L:THR685
|
4.8
|
182.4
|
1.0
|
O
|
L:CYS663
|
4.9
|
172.8
|
1.0
|
|
Zinc binding site 4 out
of 4 in 8t3w
Go back to
Zinc Binding Sites List in 8t3w
Zinc binding site 4 out
of 4 in the Structure of BRE1-Nucleosome Complex - STATE2
![](/pictures/ZN/pdb/t3/8t3w-ZN-sphere_04.jpg) Mono view
![](/pictures/ZN/pdb/t3/8t3w-ZN-sphere_04_stereo.jpg) Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Structure of BRE1-Nucleosome Complex - STATE2 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
L:Zn802
b:214.6
occ:1.00
|
SG
|
L:CYS668
|
2.3
|
189.7
|
1.0
|
SG
|
L:CYS648
|
2.3
|
189.0
|
1.0
|
SG
|
L:CYS671
|
2.3
|
191.0
|
1.0
|
SG
|
L:CYS651
|
2.3
|
190.1
|
1.0
|
CB
|
L:CYS648
|
3.0
|
189.0
|
1.0
|
CB
|
L:CYS671
|
3.2
|
191.0
|
1.0
|
CB
|
L:CYS651
|
3.3
|
190.1
|
1.0
|
N
|
L:CYS651
|
3.6
|
190.1
|
1.0
|
CB
|
L:CYS668
|
3.7
|
189.7
|
1.0
|
N
|
L:CYS671
|
4.1
|
191.0
|
1.0
|
CA
|
L:CYS651
|
4.1
|
190.1
|
1.0
|
CB
|
L:LEU650
|
4.1
|
186.6
|
1.0
|
CA
|
L:CYS671
|
4.2
|
191.0
|
1.0
|
CA
|
L:CYS648
|
4.4
|
189.0
|
1.0
|
N
|
L:CYS668
|
4.5
|
189.7
|
1.0
|
C
|
L:LEU650
|
4.6
|
186.6
|
1.0
|
CA
|
L:CYS668
|
4.6
|
189.7
|
1.0
|
OD1
|
L:ASN654
|
4.7
|
181.8
|
1.0
|
CA
|
L:LEU650
|
4.7
|
186.6
|
1.0
|
N
|
L:LEU650
|
4.8
|
186.6
|
1.0
|
C
|
L:CYS648
|
4.8
|
189.0
|
1.0
|
CB
|
L:ASN654
|
4.8
|
181.8
|
1.0
|
CB
|
L:ASN670
|
4.8
|
187.6
|
1.0
|
O
|
L:CYS648
|
4.9
|
189.0
|
1.0
|
O
|
L:CYS668
|
4.9
|
189.7
|
1.0
|
N
|
L:SER652
|
4.9
|
188.0
|
1.0
|
C
|
L:CYS651
|
5.0
|
190.1
|
1.0
|
|
Reference:
F.Zhao,
C.W.Hicks,
C.Wolberger.
Cryo-Em Structure of BRE1-Nucleosome Complex in State 2 To Be Published.
Page generated: Thu Dec 28 13:41:43 2023
|