Zinc in PDB 8t13: Cryo-Em Structure of DENV2 NS5 in Complex with Human STAT2 with the N- Terminal Domain of STAT2 Disordered

The binding sites of Zinc atom in the Cryo-Em Structure of DENV2 NS5 in Complex with Human STAT2 with the N- Terminal Domain of STAT2 Disordered (pdb code 8t13). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of DENV2 NS5 in Complex with Human STAT2 with the N- Terminal Domain of STAT2 Disordered, PDB code: 8t13:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of DENV2 NS5 in Complex with Human STAT2 with the N- Terminal Domain of STAT2 Disordered


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of DENV2 NS5 in Complex with Human STAT2 with the N- Terminal Domain of STAT2 Disordered within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1001 b:141.2 occ:1.00 NE2 B:HIS712 2.0 122.7 1.0 NE2 B:HIS714 2.0 107.7 1.0 SG B:CYS728 2.3 118.8 1.0 SG B:CYS847 2.3 140.6 1.0 CD2 B:HIS712 2.8 121.1 1.0 CD2 B:HIS714 3.0 105.5 1.0 CE1 B:HIS714 3.1 104.1 1.0 CE1 B:HIS712 3.2 123.1 1.0 CB B:CYS728 3.4 111.7 1.0 CB B:CYS847 3.8 140.0 1.0 CG B:HIS712 4.0 121.2 1.0 CG B:HIS714 4.1 103.4 1.0 ND1 B:HIS714 4.2 102.0 1.0 ND1 B:HIS712 4.2 122.7 1.0 CD2 B:LEU839 4.4 123.1 1.0 NH2 B:ARG769 4.5 110.7 1.0 CA B:CYS728 4.8 109.4 1.0 CA B:CYS847 4.9 141.1 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of DENV2 NS5 in Complex with Human STAT2 with the N- Terminal Domain of STAT2 Disordered


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of DENV2 NS5 in Complex with Human STAT2 with the N- Terminal Domain of STAT2 Disordered within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1002 b:30.0 occ:1.00 NE2 B:HIS442 1.8 111.7 1.0 SG B:CYS450 2.0 119.3 1.0 CB B:CYS447 2.2 115.4 1.0 SG B:CYS447 2.6 116.0 1.0 CE1 B:HIS442 2.8 109.5 1.0 CD2 B:HIS442 2.8 111.6 1.0 CA B:CYS447 2.8 117.7 1.0 N B:GLU448 3.4 125.3 1.0 OE1 B:GLU438 3.5 124.1 1.0 C B:CYS447 3.5 119.4 1.0 OE2 B:GLU438 3.5 126.2 1.0 CB B:CYS450 3.6 118.1 1.0 CD B:GLU438 3.9 125.0 1.0 ND1 B:HIS442 3.9 108.1 1.0 CG B:HIS442 4.0 109.3 1.0 N B:CYS447 4.2 117.2 1.0 N B:THR449 4.2 116.3 1.0 N B:CYS450 4.3 116.5 1.0 O B:LYS446 4.5 119.2 1.0 O B:CYS447 4.6 119.1 1.0 CA B:CYS450 4.6 116.2 1.0 CA B:GLU448 4.7 126.6 1.0 C B:THR449 4.7 113.0 1.0 C B:LYS446 4.8 120.2 1.0 C B:GLU448 4.9 125.3 1.0

M.Biswal, J.Lu, J.Song. Cryo-Em Structure of DENV2 NS5 in Complex with Human STAT2 with the N-Terminal Domain of STAT2 Disordered To Be Published.