Zinc in PDB 8sic: Crystal Structure of Epstein-Barr Virus Glycoprotein 350 (GP350) in Complex with CY137C02, A Monoclonal Antibody Isolated From Macaques Immunized with A GP350 Nanoparticle Vaccine

The structure of Crystal Structure of Epstein-Barr Virus Glycoprotein 350 (GP350) in Complex with CY137C02, A Monoclonal Antibody Isolated From Macaques Immunized with A GP350 Nanoparticle Vaccine, PDB code: 8sic was solved by M.G.Joyce, J.L.Jensen, W.H.Chen, M.Kanekiyo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	71.38 / 2.76
Space group	P 21 2 21
Cell size a, b, c (Å), α, β, γ (°)	69.047, 71.377, 395.083, 90, 90, 90
R / Rfree (%)	24.6 / 29.5

The binding sites of Zinc atom in the Crystal Structure of Epstein-Barr Virus Glycoprotein 350 (GP350) in Complex with CY137C02, A Monoclonal Antibody Isolated From Macaques Immunized with A GP350 Nanoparticle Vaccine (pdb code 8sic). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Epstein-Barr Virus Glycoprotein 350 (GP350) in Complex with CY137C02, A Monoclonal Antibody Isolated From Macaques Immunized with A GP350 Nanoparticle Vaccine, PDB code: 8sic:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Epstein-Barr Virus Glycoprotein 350 (GP350) in Complex with CY137C02, A Monoclonal Antibody Isolated From Macaques Immunized with A GP350 Nanoparticle Vaccine


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Epstein-Barr Virus Glycoprotein 350 (GP350) in Complex with CY137C02, A Monoclonal Antibody Isolated From Macaques Immunized with A GP350 Nanoparticle Vaccine within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn507 b:83.3 occ:1.00 C E:HIS429 2.3 116.4 1.0 NE2 E:HIS426 2.3 79.0 1.0 NE2 G:HIS238 2.3 80.9 1.0 OE2 G:GLU101 2.4 86.4 1.0 OE1 G:GLU101 2.5 61.5 1.0 O E:HIS429 2.5 120.8 1.0 CD G:GLU101 2.7 75.1 1.0 CA E:HIS429 2.9 118.4 1.0 CD2 E:HIS426 2.9 81.0 1.0 CE1 G:HIS238 3.1 74.7 1.0 CD2 G:HIS238 3.1 70.5 1.0 CE1 E:HIS426 3.3 77.7 1.0 N E:HIS429 3.8 125.1 1.0 CG E:HIS426 4.0 76.8 1.0 CB E:HIS429 4.0 124.7 1.0 ND1 G:HIS238 4.0 76.0 1.0 CG G:HIS238 4.1 68.0 1.0 CG E:HIS429 4.1 128.3 1.0 CG2 G:VAL239 4.1 75.7 1.0 ND1 E:HIS426 4.2 75.0 1.0 CG G:GLU101 4.2 74.7 1.0 ND1 E:HIS429 4.4 126.1 1.0 CD2 E:HIS429 4.5 118.7 1.0 C E:HIS428 4.6 128.3 1.0 O E:HIS427 4.7 105.7 1.0 O E:HIS428 4.8 135.6 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Epstein-Barr Virus Glycoprotein 350 (GP350) in Complex with CY137C02, A Monoclonal Antibody Isolated From Macaques Immunized with A GP350 Nanoparticle Vaccine


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Epstein-Barr Virus Glycoprotein 350 (GP350) in Complex with CY137C02, A Monoclonal Antibody Isolated From Macaques Immunized with A GP350 Nanoparticle Vaccine within 5.0Å range: probe atom residue distance (Å) B Occ G:Zn510 b:130.8 occ:1.00 OE1 E:GLU101 2.1 93.0 1.0 O G:HIS429 2.1 118.7 1.0 NE2 E:HIS238 2.2 100.2 1.0 ND1 G:HIS426 2.3 115.3 1.0 OE2 E:GLU101 2.5 94.1 1.0 CD E:GLU101 2.5 86.4 1.0 C G:HIS429 2.6 125.2 1.0 CD2 E:HIS238 3.1 95.5 1.0 ND1 G:HIS429 3.1 144.2 1.0 CE1 E:HIS238 3.2 91.3 1.0 CG G:HIS426 3.2 112.9 1.0 CE1 G:HIS426 3.3 117.8 1.0 CB G:HIS426 3.4 110.1 1.0 CA G:HIS429 3.9 134.5 1.0 CG E:GLU101 4.0 76.7 1.0 CG G:HIS429 4.0 141.4 1.0 CE1 G:HIS429 4.0 140.1 1.0 CB G:HIS429 4.0 134.3 1.0 ND1 E:HIS238 4.2 85.7 1.0 CG E:HIS238 4.3 84.5 1.0 CG2 E:VAL239 4.3 96.9 1.0 CD2 G:HIS426 4.4 114.1 1.0 NE2 G:HIS426 4.4 117.1 1.0 CB E:GLU101 4.8 71.5 1.0 N G:HIS429 4.8 144.9 1.0 CA G:HIS426 4.9 108.2 1.0

M.G.Joyce, J.L.Jensen, W.H.Chen, M.Kanekiyo. Crystal Structure of Epstein-Barr Virus Glycoprotein 350 (GP350) in Complex with CY137C02, A Monoclonal Antibody Isolated From Macaques Immunized with A GP350 Nanoparticle Vaccine To Be Published.