Zinc in PDB 8r8r: Cryo-Em Structure of the Human Mpsf with Papoa C-Terminus Peptide (Papoac)

The binding sites of Zinc atom in the Cryo-Em Structure of the Human Mpsf with Papoa C-Terminus Peptide (Papoac) (pdb code 8r8r). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Cryo-Em Structure of the Human Mpsf with Papoa C-Terminus Peptide (Papoac), PDB code: 8r8r:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Cryo-Em Structure of the Human Mpsf with Papoa C-Terminus Peptide (Papoac)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of the Human Mpsf with Papoa C-Terminus Peptide (Papoac) within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn301 b:96.9 occ:1.00 NE2 C:HIS59 2.1 63.8 1.0 SG C:CYS49 2.3 72.1 1.0 SG C:CYS41 2.3 54.9 1.0 SG C:CYS55 2.3 66.8 1.0 CD2 C:HIS59 3.0 60.8 1.0 CE1 C:HIS59 3.1 60.1 1.0 CB C:CYS55 3.2 61.2 1.0 CB C:CYS41 3.3 46.7 1.0 CB C:CYS49 3.6 72.5 1.0 CG C:HIS59 4.2 59.8 1.0 ND1 C:HIS59 4.2 58.5 1.0 CB C:PHE44 4.5 60.4 1.0 O C:PHE57 4.6 51.6 1.0 CA C:CYS41 4.7 47.6 1.0 CA C:CYS55 4.7 57.8 1.0 CB C:PHE57 4.8 46.8 1.0 CA C:CYS49 4.9 72.4 1.0

Zinc binding site 2 out of 3 in the Cryo-Em Structure of the Human Mpsf with Papoa C-Terminus Peptide (Papoac)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of the Human Mpsf with Papoa C-Terminus Peptide (Papoac) within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn302 b:107.0 occ:1.00 NE2 C:HIS86 2.1 65.1 1.0 SG C:CYS68 2.3 75.4 1.0 SG C:CYS82 2.3 81.2 1.0 SG C:CYS76 2.3 72.2 1.0 CE1 C:HIS86 3.0 61.9 1.0 CD2 C:HIS86 3.1 68.1 1.0 CB C:CYS68 3.1 67.8 1.0 CB C:CYS82 3.4 80.4 1.0 CB C:CYS76 3.7 67.1 1.0 CB C:TRP71 4.1 54.8 1.0 ND1 C:HIS86 4.2 62.2 1.0 CG C:HIS86 4.2 64.7 1.0 CA C:CYS68 4.6 68.1 1.0 N C:TRP71 4.6 57.4 1.0 O C:PHE84 4.7 75.7 1.0 CA C:CYS82 4.8 81.8 1.0 CA C:TRP71 4.9 57.0 1.0 CA C:CYS76 4.9 65.2 1.0 N6 E:A2 4.9 76.4 1.0 CB C:PHE84 5.0 72.2 1.0

Zinc binding site 3 out of 3 in the Cryo-Em Structure of the Human Mpsf with Papoa C-Terminus Peptide (Papoac)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Cryo-Em Structure of the Human Mpsf with Papoa C-Terminus Peptide (Papoac) within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn303 b:128.2 occ:1.00 NE2 C:HIS114 2.1 86.4 1.0 SG C:CYS110 2.3 82.2 1.0 SG C:CYS96 2.3 82.5 1.0 SG C:CYS105 2.3 94.8 1.0 CE1 C:HIS114 3.0 85.9 1.0 CD2 C:HIS114 3.2 84.8 1.0 CB C:CYS105 3.2 90.6 1.0 CB C:CYS110 3.3 82.2 1.0 CB C:CYS96 3.4 80.5 1.0 ND1 C:HIS114 4.1 85.6 1.0 CG C:HIS114 4.3 85.3 1.0 CB C:TYR99 4.5 86.3 1.0 CA C:CYS105 4.6 91.7 1.0 CA C:CYS110 4.7 83.8 1.0 CA C:CYS96 4.8 80.9 1.0 O C:PHE112 4.8 80.0 1.0 N6 E:A5 4.8 79.9 1.0 CB C:PHE112 4.9 78.8 1.0

S.Todesca, F.Sandmeir, A.Keidel, E.Conti. Molecular Basis of Human Polya Polymerase Recruitment By Mpsf. Rna 2024.
ISSN: ESSN 1469-9001
PubMed: 38538052
DOI: 10.1261/RNA.079915.123