Zinc in PDB 8r2d: Integrator Cleavage Module Assembly Intermediate

The binding sites of Zinc atom in the Integrator Cleavage Module Assembly Intermediate (pdb code 8r2d). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Integrator Cleavage Module Assembly Intermediate, PDB code: 8r2d:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Integrator Cleavage Module Assembly Intermediate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Integrator Cleavage Module Assembly Intermediate within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn700 b:63.8 occ:1.00 OD2 C:ASP178 1.9 62.0 1.0 ND1 C:HIS70 2.1 43.6 1.0 NE2 C:HIS68 2.2 40.3 1.0 SG A:CYS820 2.5 74.1 1.0 NE2 C:HIS157 2.6 55.0 1.0 CD2 C:HIS68 2.7 40.3 1.0 CG C:HIS70 3.0 43.6 1.0 CE1 C:HIS70 3.2 43.6 1.0 CG C:ASP178 3.2 62.0 1.0 CB C:HIS70 3.2 43.6 1.0 CB A:CYS820 3.2 74.1 1.0 CE1 C:HIS68 3.4 40.3 1.0 CE1 C:HIS157 3.5 55.0 1.0 CD2 C:HIS157 3.6 55.0 1.0 ZN C:ZN701 3.8 55.8 1.0 OD1 C:ASP178 3.9 62.0 1.0 CG C:HIS68 4.0 40.3 1.0 CD2 C:HIS70 4.2 43.6 1.0 CB C:ASP178 4.2 62.0 1.0 NE2 C:HIS70 4.2 43.6 1.0 ND1 C:HIS68 4.3 40.3 1.0 ND1 C:HIS157 4.6 55.0 1.0 CA C:HIS70 4.6 43.6 1.0 CG C:HIS157 4.7 55.0 1.0 CA A:CYS820 4.7 74.1 1.0 CD2 C:HIS73 4.8 47.6 1.0 NE2 C:HIS73 4.9 47.6 1.0 N C:HIS70 4.9 43.6 1.0

Zinc binding site 2 out of 2 in the Integrator Cleavage Module Assembly Intermediate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Integrator Cleavage Module Assembly Intermediate within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn701 b:55.8 occ:1.00 NE2 C:HIS414 2.0 64.4 1.0 NE2 C:HIS73 2.2 47.6 1.0 SG A:CYS820 2.4 74.1 1.0 CD2 C:HIS414 2.5 64.4 1.0 CE1 C:HIS414 2.6 64.4 1.0 OD1 C:ASP178 2.9 62.0 1.0 CD2 C:HIS73 3.0 47.6 1.0 ND1 C:HIS414 3.2 64.4 1.0 CG C:HIS414 3.2 64.4 1.0 CE1 C:HIS73 3.3 47.6 1.0 OD2 C:ASP178 3.3 62.0 1.0 CG C:ASP178 3.5 62.0 1.0 NE2 C:HIS68 3.7 40.3 1.0 ZN C:ZN700 3.8 63.8 1.0 CE1 C:HIS68 3.9 40.3 1.0 CB A:CYS820 4.1 74.1 1.0 CG C:HIS73 4.2 47.6 1.0 ND1 C:HIS73 4.3 47.6 1.0 CB C:HIS414 4.5 64.4 1.0 CA A:CYS820 4.8 74.1 1.0 CB C:ASP72 4.9 52.7 1.0 CB C:ASP178 5.0 62.0 1.0

K.Sabath, C.Qiu, S.Jonas. Assembly Mechanism of Integrator'S Rna Cleavage Module. Mol.Cell 2024.
ISSN: ISSN 1097-2765
PubMed: 39032489
DOI: 10.1016/J.MOLCEL.2024.06.032