Zinc in PDB 8qoy: Capsular Polysaccharide Synthesis Multienzyme of Actinobacillus Pleuropneumoniae Serotype 3

The structure of Capsular Polysaccharide Synthesis Multienzyme of Actinobacillus Pleuropneumoniae Serotype 3, PDB code: 8qoy was solved by V.Di Domenico, C.Litschko, J.Schulze, A.Bethe, J.O.Cifuente, A.Marina, I.Budde, T.A.Mast, M.Sulewska, M.Berger, F.Buettner, R.Gerardy-Schahn, T.Fiebig, M.E.Guerin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.55 / 3.00
Space group	P 3 2 1
Cell size a, b, c (Å), α, β, γ (°)	207.911, 207.911, 93.659, 90, 90, 120
R / Rfree (%)	18.3 / 22.1

The binding sites of Zinc atom in the Capsular Polysaccharide Synthesis Multienzyme of Actinobacillus Pleuropneumoniae Serotype 3 (pdb code 8qoy). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Capsular Polysaccharide Synthesis Multienzyme of Actinobacillus Pleuropneumoniae Serotype 3, PDB code: 8qoy:

Zinc binding site 1 out of 1 in the Capsular Polysaccharide Synthesis Multienzyme of Actinobacillus Pleuropneumoniae Serotype 3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Capsular Polysaccharide Synthesis Multienzyme of Actinobacillus Pleuropneumoniae Serotype 3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1203 b:35.4 occ:1.00 OD2 A:ASP915 2.3 48.1 1.0 ND1 A:HIS885 2.3 49.7 1.0 NE2 A:HIS1143 2.3 37.3 1.0 NE2 A:HIS1145 2.3 45.7 1.0 OD1 A:ASP915 2.9 40.5 1.0 CD2 A:HIS1145 2.9 39.4 1.0 CG A:ASP915 2.9 39.1 1.0 CG A:HIS885 3.1 40.6 1.0 CE1 A:HIS885 3.1 39.9 1.0 CD2 A:HIS1143 3.2 34.7 1.0 CE1 A:HIS1143 3.3 43.7 1.0 CE1 A:HIS1145 3.4 52.9 1.0 CB A:HIS885 3.5 34.4 1.0 N A:HIS885 3.7 42.7 1.0 NE2 A:HIS885 4.1 38.9 1.0 CD2 A:HIS885 4.1 43.5 1.0 CG A:HIS1145 4.2 49.7 1.0 CA A:HIS885 4.2 35.8 1.0 CG A:HIS1143 4.3 36.6 1.0 ND1 A:HIS1143 4.3 46.7 1.0 C A:LYS884 4.3 37.1 1.0 ND1 A:HIS1145 4.4 62.8 1.0 CB A:ASP915 4.4 35.5 1.0 CA A:LYS884 4.5 36.6 1.0 N A:ASP915 4.8 38.0 1.0 N A:LYS884 4.9 41.5 1.0

C.Litschko, V.Di Domenico, J.Schulze, A.Bethe, O.G.Ovchinnikova, S.Li, T.Voskuilen, J.O.Cifuente, A.Marina, I.Budde, T.A.Mast, M.Sulewska, M.Berger, F.Buettner, R.Gerardy-Schahn, T.L.Lower, C.Whitfield, J.D.C.Codee, M.Schubert, M.E.Guerin, T.Fiebig. Transition Transferases Prime Bacterial Capsule Polymerization Nat.Chem.Biol. 2024.
ISSN: ESSN 1552-4469
DOI: 10.1038/S41589-024-01664-8