Zinc in PDB 8pbl: E. Coli Rna Polymerase Elongation Complex Stalled at Thymine Dimer Lesion

Enzymatic activity of E. Coli Rna Polymerase Elongation Complex Stalled at Thymine Dimer Lesion

All present enzymatic activity of E. Coli Rna Polymerase Elongation Complex Stalled at Thymine Dimer Lesion:
2.7.7.6;

Other elements in 8pbl:

The structure of E. Coli Rna Polymerase Elongation Complex Stalled at Thymine Dimer Lesion also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the E. Coli Rna Polymerase Elongation Complex Stalled at Thymine Dimer Lesion (pdb code 8pbl). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the E. Coli Rna Polymerase Elongation Complex Stalled at Thymine Dimer Lesion, PDB code: 8pbl:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 8pbl

Go back to Zinc Binding Sites List in 8pbl
Zinc binding site 1 out of 2 in the E. Coli Rna Polymerase Elongation Complex Stalled at Thymine Dimer Lesion


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of E. Coli Rna Polymerase Elongation Complex Stalled at Thymine Dimer Lesion within 5.0Å range:
probe atom residue distance (Å) B Occ
G:Zn1501

b:296.9
occ:1.00
SG G:CYS88 2.3 245.2 1.0
SG G:CYS85 2.3 276.9 1.0
SG G:CYS72 2.3 254.7 1.0
SG G:CYS70 2.3 258.0 1.0
CB G:CYS70 2.5 255.0 1.0
CB G:CYS85 3.0 274.8 1.0
CB G:CYS88 3.7 242.7 1.0
CB G:CYS72 3.7 253.6 1.0
CA G:CYS70 3.9 254.1 1.0
N G:CYS88 3.9 243.1 1.0
N G:CYS72 4.1 254.1 1.0
CA G:CYS88 4.4 242.6 1.0
O G:VAL90 4.4 225.7 1.0
CA G:CYS85 4.5 275.2 1.0
N G:LEU71 4.5 235.8 1.0
CA G:CYS72 4.5 253.9 1.0
C G:CYS70 4.5 253.9 1.0
CB G:LYS87 4.7 248.3 1.0
N G:CYS70 4.9 253.7 1.0
C G:CYS85 4.9 275.0 1.0
CD2 G:TYR75 4.9 265.3 1.0
C G:LYS87 4.9 247.8 1.0
N G:VAL90 4.9 224.4 1.0
N G:GLY73 5.0 265.1 1.0
N G:GLY89 5.0 229.4 1.0
N G:LYS87 5.0 248.7 1.0

Zinc binding site 2 out of 2 in 8pbl

Go back to Zinc Binding Sites List in 8pbl
Zinc binding site 2 out of 2 in the E. Coli Rna Polymerase Elongation Complex Stalled at Thymine Dimer Lesion


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of E. Coli Rna Polymerase Elongation Complex Stalled at Thymine Dimer Lesion within 5.0Å range:
probe atom residue distance (Å) B Occ
G:Zn1502

b:150.4
occ:1.00
SG G:CYS895 2.3 128.7 1.0
SG G:CYS898 2.3 134.1 1.0
SG G:CYS888 2.3 124.4 1.0
SG G:CYS814 2.3 129.6 1.0
CB G:CYS888 3.2 119.7 1.0
CB G:CYS898 3.2 123.3 1.0
NH2 G:ARG883 3.4 119.0 1.0
CB G:CYS814 3.4 125.1 1.0
CA G:CYS888 3.6 119.8 1.0
CB G:CYS895 3.7 122.1 1.0
N G:ASP889 4.1 144.7 1.0
CG2 G:THR890 4.3 125.5 1.0
C G:CYS888 4.3 123.2 1.0
N G:CYS895 4.3 117.2 1.0
N G:CYS898 4.3 119.0 1.0
CA G:CYS898 4.3 119.9 1.0
N G:CYS814 4.4 124.7 1.0
CZ G:ARG883 4.4 124.0 1.0
CG2 G:THR816 4.4 132.8 1.0
CA G:CYS814 4.5 129.0 1.0
NE G:ARG883 4.5 123.2 1.0
CA G:CYS895 4.5 116.5 1.0
OG1 G:THR890 4.7 116.5 1.0
N G:CYS888 4.9 117.8 1.0
O G:CYS895 4.9 119.6 1.0

Reference:

J.Woodgate, H.Mosai, P.Brazda, F.Stevenson-Jones, N.Zenkin. Coupled Translation Specifically Destroys Non-Functional Transcription Elongation Complexes Stalled By Dna Lesions To Be Published.
Page generated: Thu Oct 31 09:22:05 2024

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