Zinc in PDB 9b85: Cryo-Em Structure of Human Dynactin Complex Bound to Chlamydia Effector DRE1

The binding sites of Zinc atom in the Cryo-Em Structure of Human Dynactin Complex Bound to Chlamydia Effector DRE1 (pdb code 9b85). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Cryo-Em Structure of Human Dynactin Complex Bound to Chlamydia Effector DRE1, PDB code: 9b85:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Cryo-Em Structure of Human Dynactin Complex Bound to Chlamydia Effector DRE1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Human Dynactin Complex Bound to Chlamydia Effector DRE1 within 5.0Å range: probe atom residue distance (Å) B Occ K:Zn501 b:600.0 occ:1.00 OE2 K:GLU35 1.9 600.0 1.0 OE1 K:GLU35 2.2 600.0 1.0 CD K:GLU35 2.3 600.0 1.0 HG3 K:LYS279 3.3 720.0 1.0 CG K:GLU35 3.8 600.0 1.0 HE3 K:LYS279 4.1 720.0 1.0 HB3 K:LYS279 4.1 720.0 1.0 HG3 K:GLU35 4.2 720.0 1.0 HD2 K:LYS279 4.2 720.0 1.0 CG K:LYS279 4.2 600.0 1.0 HG2 K:GLU35 4.3 720.0 1.0 HB2 K:CYS33 4.4 720.0 1.0 HB2 K:LYS279 4.6 720.0 1.0 CB K:LYS279 4.6 600.0 1.0 HB2 K:GLU35 4.6 720.0 1.0 CD K:LYS279 4.7 600.0 1.0 CB K:GLU35 4.7 600.0 1.0 HB3 K:GLU35 4.7 720.0 1.0 HG K:CYS33 4.9 720.0 1.0 CE K:LYS279 4.9 600.0 1.0 SG K:CYS33 4.9 600.0 1.0

Zinc binding site 2 out of 3 in the Cryo-Em Structure of Human Dynactin Complex Bound to Chlamydia Effector DRE1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of Human Dynactin Complex Bound to Chlamydia Effector DRE1 within 5.0Å range: probe atom residue distance (Å) B Occ K:Zn502 b:567.4 occ:1.00 OE1 K:GLU56 2.0 567.8 1.0 OE2 K:GLU56 2.0 578.6 1.0 OD1 K:ASN72 2.2 562.1 1.0 CD K:GLU56 2.3 574.0 1.0 CG K:ASN72 3.2 599.1 1.0 HB2 K:ASN72 3.3 703.8 1.0 HG K:CYS54 3.6 720.0 1.0 CG K:GLU56 3.8 590.0 1.0 CB K:ASN72 3.8 586.5 1.0 ND2 K:ASN72 4.2 562.1 1.0 H K:ASN72 4.3 614.7 1.0 HG3 K:GLU56 4.3 707.9 1.0 HG2 K:GLU56 4.3 707.9 1.0 HD21 K:ASN72 4.4 674.5 1.0 HB3 K:ALA71 4.5 650.8 1.0 HB3 K:ASN72 4.5 703.8 1.0 HB3 K:GLU56 4.6 720.0 1.0 HB2 K:GLU56 4.6 720.0 1.0 CB K:GLU56 4.6 600.0 1.0 HE3 K:MET58 4.7 716.1 1.0 N K:ASN72 4.8 512.2 1.0 SG K:CYS54 4.8 600.0 1.0 CA K:ASN72 5.0 513.1 1.0

Zinc binding site 3 out of 3 in the Cryo-Em Structure of Human Dynactin Complex Bound to Chlamydia Effector DRE1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Cryo-Em Structure of Human Dynactin Complex Bound to Chlamydia Effector DRE1 within 5.0Å range: probe atom residue distance (Å) B Occ K:Zn503 b:532.1 occ:1.00 SG K:CYS76 2.4 574.4 1.0 HB3 K:CYS76 2.4 617.1 1.0 SG K:CYS111 2.5 589.1 1.0 SG K:CYS79 2.5 544.7 1.0 SG K:CYS114 2.6 570.8 1.0 HB2 K:CYS111 2.6 711.6 1.0 CB K:CYS76 2.7 514.3 1.0 CB K:CYS111 2.9 593.0 1.0 HB2 K:CYS76 2.9 617.1 1.0 HB3 K:CYS111 3.0 711.6 1.0 HG K:CYS79 3.1 653.7 1.0 HG K:CYS111 3.1 706.9 1.0 H K:CYS79 3.2 720.0 1.0 HB3 K:HIS81 3.4 683.0 1.0 HG K:CYS76 3.5 689.2 1.0 HG K:CYS114 3.5 685.0 1.0 HB3 K:TRP116 3.5 720.0 1.0 H K:CYS114 3.6 714.0 1.0 H K:HIS81 3.8 634.9 1.0 CB K:CYS79 3.8 578.0 1.0 N K:CYS79 3.9 600.0 1.0 HB3 K:CYS79 4.0 693.7 1.0 CB K:CYS114 4.0 576.1 1.0 HB3 K:CYS114 4.0 691.3 1.0 HD21 K:LEU83 4.2 687.5 1.0 CA K:CYS76 4.2 537.0 1.0 HB3 K:PHE113 4.2 720.0 1.0 HD23 K:LEU83 4.3 687.5 1.0 HB2 K:TRP116 4.3 720.0 1.0 H K:TRP116 4.4 720.0 1.0 CA K:CYS111 4.4 600.0 1.0 O K:HIS81 4.4 497.9 1.0 HA3 K:GLY78 4.4 666.3 1.0 H K:GLY78 4.4 655.2 1.0 CA K:CYS79 4.4 578.1 1.0 CB K:HIS81 4.4 569.2 1.0 CB K:TRP116 4.4 600.0 1.0 N K:CYS114 4.5 595.0 1.0 HD2 K:PHE113 4.6 720.0 1.0 H K:MET80 4.6 583.2 1.0 N K:HIS81 4.6 529.0 1.0 HA2 K:GLY78 4.7 666.3 1.0 O K:CYS76 4.7 400.5 1.0 HA K:CYS111 4.7 720.0 1.0 HB2 K:HIS81 4.7 683.0 1.0 C K:CYS76 4.7 550.4 1.0 HB2 K:CYS79 4.7 693.7 1.0 CD2 K:LEU83 4.7 572.9 1.0 HB2 K:CYS114 4.8 691.3 1.0 HA K:CYS76 4.8 644.4 1.0 C K:GLY78 4.8 560.2 1.0 H K:CYS76 4.8 642.8 1.0 CA K:CYS114 4.8 600.0 1.0 H K:PHE113 4.9 720.0 1.0 C K:CYS79 4.9 593.9 1.0 N K:MET80 4.9 486.0 1.0 CA K:GLY78 4.9 555.3 1.0 HD2 K:HIS81 4.9 676.9 1.0 CA K:HIS81 4.9 571.4 1.0 N K:GLY78 4.9 546.0 1.0

J.Sherry, K.I.Pawar, L.Dolat, E.Smith, I.C.Chang, K.Pha, R.Kaake, D.L.Swaney, C.Herrera, E.Mcmahon, R.J.Bastidas, J.R.Johnson, R.H.Valdivia, N.J.Krogan, C.A.Elwell, K.Verba, J.N.Engel. The Chlamydia Effector DRE1 Binds Dynactin to Reposition Host Organelles During Infection. Cell Rep V. 44 15509 2025.
ISSN: ESSN 2211-1247
PubMed: 40186871
DOI: 10.1016/J.CELREP.2025.115509