Atomistry » Zinc » PDB 8otr-8p7r » 8p4b
Atomistry »
  Zinc »
    PDB 8otr-8p7r »
      8p4b »

Zinc in PDB 8p4b: Structural Insights Into Human Co-Transcriptional Capping - Structure 2

Enzymatic activity of Structural Insights Into Human Co-Transcriptional Capping - Structure 2

All present enzymatic activity of Structural Insights Into Human Co-Transcriptional Capping - Structure 2:
2.7.7.50; 2.7.7.6; 3.6.1.74;

Other elements in 8p4b:

The structure of Structural Insights Into Human Co-Transcriptional Capping - Structure 2 also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Structural Insights Into Human Co-Transcriptional Capping - Structure 2 (pdb code 8p4b). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 8 binding sites of Zinc where determined in the Structural Insights Into Human Co-Transcriptional Capping - Structure 2, PDB code: 8p4b:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Zinc binding site 1 out of 8 in 8p4b

Go back to Zinc Binding Sites List in 8p4b
Zinc binding site 1 out of 8 in the Structural Insights Into Human Co-Transcriptional Capping - Structure 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structural Insights Into Human Co-Transcriptional Capping - Structure 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn2001

b:110.1
occ:1.00
 SG A:CYS74 2.3 95.8 1.0
SG A:CYS71 2.3 99.8 1.0
NE2 A:HIS84 2.3 83.0 1.0
CB A:CYS71 2.6 99.8 1.0
CD2 A:HIS84 2.8 83.0 1.0
SG A:CYS81 3.3 92.4 1.0
CB A:CYS81 3.4 92.4 1.0
CE1 A:HIS84 3.6 83.0 1.0
O A:PRO82 3.7 82.6 1.0
O A:CYS74 3.7 95.8 1.0
CB A:CYS74 3.9 95.8 1.0
CG A:HIS84 4.1 83.0 1.0
OG1 A:THR73 4.1 97.2 1.0
CA A:CYS71 4.1 99.8 1.0
N A:CYS74 4.2 95.8 1.0
CA A:CYS74 4.4 95.8 1.0
ND1 A:HIS84 4.4 83.0 1.0
CA A:GLY63 4.4 92.5 1.0
C A:CYS74 4.4 95.8 1.0
O A:GLN62 4.6 87.8 1.0
C A:CYS71 4.7 99.8 1.0
CA A:CYS81 4.8 92.4 1.0
N A:CYS71 4.9 99.8 1.0
C A:PRO82 4.9 82.6 1.0
C A:GLY63 4.9 92.5 1.0
O A:ARG61 5.0 92.8 1.0

Zinc binding site 2 out of 8 in 8p4b

Go back to Zinc Binding Sites List in 8p4b
Zinc binding site 2 out of 8 in the Structural Insights Into Human Co-Transcriptional Capping - Structure 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structural Insights Into Human Co-Transcriptional Capping - Structure 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn2002

b:153.2
occ:1.00
 SG A:CYS114 2.3 130.9 1.0
SG A:CYS111 2.3 132.7 1.0
CB A:CYS114 3.1 130.9 1.0
CE1 A:TYR187 3.3 139.1 1.0
SG A:CYS184 3.4 140.0 1.0
CD1 A:TYR187 3.4 139.1 1.0
N A:CYS184 3.5 140.0 1.0
CZ A:TYR187 3.9 139.1 1.0
CB A:CYS111 3.9 132.7 1.0
CA A:GLY183 4.0 139.0 1.0
CG A:TYR187 4.1 139.1 1.0
CB A:CYS184 4.2 140.0 1.0
C A:GLY183 4.3 139.0 1.0
CD A:LYS116 4.3 128.9 1.0
CE2 A:TYR187 4.4 139.1 1.0
CA A:CYS184 4.5 140.0 1.0
O A:GLY182 4.5 135.6 1.0
OH A:TYR187 4.5 139.1 1.0
CD2 A:TYR187 4.5 139.1 1.0
CA A:CYS114 4.6 130.9 1.0
O A:PHE112 4.6 125.8 1.0
CB A:LYS116 4.8 128.9 1.0
NZ A:LYS116 4.9 128.9 1.0
CB A:TYR187 4.9 139.1 1.0
N A:GLY185 4.9 140.5 1.0
CG A:LYS116 4.9 128.9 1.0

Zinc binding site 3 out of 8 in 8p4b

Go back to Zinc Binding Sites List in 8p4b
Zinc binding site 3 out of 8 in the Structural Insights Into Human Co-Transcriptional Capping - Structure 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structural Insights Into Human Co-Transcriptional Capping - Structure 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn1201

b:124.0
occ:1.00
 SG B:CYS1122 2.3 93.7 1.0
SG B:CYS1119 2.3 93.3 1.0
SG B:CYS1137 2.3 102.5 1.0
CB B:CYS1119 2.5 93.3 1.0
SG B:CYS1140 2.7 106.3 1.0
CB B:CYS1137 3.4 102.5 1.0
CB B:CYS1140 3.6 106.3 1.0
CB B:CYS1122 3.7 93.7 1.0
N B:CYS1122 3.7 93.7 1.0
O B:CYS1122 3.9 93.7 1.0
CA B:CYS1119 4.0 93.3 1.0
CA B:CYS1122 4.1 93.7 1.0
ND2 B:ASN1142 4.3 105.5 1.0
O B:CYS1137 4.4 102.5 1.0
C B:CYS1122 4.4 93.7 1.0
CB B:LEU1121 4.6 92.0 1.0
C B:CYS1119 4.7 93.3 1.0
CA B:CYS1137 4.7 102.5 1.0
N B:CYS1119 4.7 93.3 1.0
C B:LEU1121 4.8 92.0 1.0
C B:CYS1137 4.8 102.5 1.0
N B:LEU1121 4.9 92.0 1.0
CA B:CYS1140 4.9 106.3 1.0
CG B:ASN1142 5.0 105.5 1.0

Zinc binding site 4 out of 8 in 8p4b

Go back to Zinc Binding Sites List in 8p4b
Zinc binding site 4 out of 8 in the Structural Insights Into Human Co-Transcriptional Capping - Structure 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Structural Insights Into Human Co-Transcriptional Capping - Structure 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn301

b:130.6
occ:1.00
 SG C:CYS94 2.3 89.9 1.0
SG C:CYS90 2.3 101.4 1.0
SG C:CYS88 2.3 94.9 1.0
SG C:CYS97 2.3 85.0 1.0
CB C:CYS88 3.1 94.9 1.0
CB C:CYS97 3.2 85.0 1.0
CB C:CYS90 3.5 101.4 1.0
CB C:CYS94 3.7 89.9 1.0
N C:CYS97 3.9 85.0 1.0
N C:CYS94 4.0 89.9 1.0
CA C:CYS97 4.2 85.0 1.0
CA C:CYS94 4.3 89.9 1.0
N C:CYS90 4.4 101.4 1.0
CA C:CYS88 4.5 94.9 1.0
CA C:CYS90 4.5 101.4 1.0
C C:GLU96 4.6 86.4 1.0
O C:CYS94 4.6 89.9 1.0
CB C:GLU96 4.7 86.4 1.0
C C:CYS94 4.8 89.9 1.0
C C:CYS88 4.8 94.9 1.0
C C:PHE93 4.8 86.7 1.0
O C:GLU91 4.8 100.4 1.0

Zinc binding site 5 out of 8 in 8p4b

Go back to Zinc Binding Sites List in 8p4b
Zinc binding site 5 out of 8 in the Structural Insights Into Human Co-Transcriptional Capping - Structure 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Structural Insights Into Human Co-Transcriptional Capping - Structure 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
I:Zn201

b:161.8
occ:1.00
 SG I:CYS42 2.3 137.6 1.0
SG I:CYS20 2.3 127.8 1.0
SG I:CYS39 2.3 137.5 1.0
SG I:CYS17 2.3 128.6 1.0
CB I:CYS39 3.3 137.5 1.0
CB I:CYS17 3.3 128.6 1.0
CB I:CYS42 3.8 137.6 1.0
CB I:CYS20 3.9 127.8 1.0
N I:CYS20 4.0 127.8 1.0
N I:CYS42 4.0 137.6 1.0
CB I:GLU19 4.3 129.2 1.0
CA I:CYS42 4.4 137.6 1.0
CA I:CYS20 4.5 127.8 1.0
CB I:ASN41 4.5 131.9 1.0
CA I:CYS39 4.7 137.5 1.0
O I:CYS42 4.8 137.6 1.0
CA I:CYS17 4.8 128.6 1.0
CB I:TYR44 4.9 135.8 1.0
ND2 I:ASN22 4.9 123.9 1.0
C I:CYS42 4.9 137.6 1.0
CG I:GLU19 4.9 129.2 1.0
C I:CYS20 4.9 127.8 1.0
C I:GLU19 5.0 129.2 1.0
CB I:ASN22 5.0 123.9 1.0

Zinc binding site 6 out of 8 in 8p4b

Go back to Zinc Binding Sites List in 8p4b
Zinc binding site 6 out of 8 in the Structural Insights Into Human Co-Transcriptional Capping - Structure 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Structural Insights Into Human Co-Transcriptional Capping - Structure 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
I:Zn202

b:142.5
occ:1.00
 SG I:CYS119 2.3 119.3 1.0
SG I:CYS86 2.3 117.5 1.0
SG I:CYS114 2.3 113.3 1.0
SG I:CYS89 2.3 122.4 1.0
CB I:CYS86 2.8 117.5 1.0
CB I:CYS114 3.2 113.3 1.0
CB I:CYS119 3.6 119.3 1.0
CB I:CYS89 3.8 122.4 1.0
CB I:HIS91 4.1 116.6 1.0
N I:CYS89 4.3 122.4 1.0
CA I:CYS86 4.3 117.5 1.0
CB I:HIS121 4.4 112.9 1.0
O I:THR115 4.5 112.2 1.0
CA I:CYS89 4.5 122.4 1.0
N I:HIS91 4.5 116.6 1.0
CA I:CYS114 4.7 113.3 1.0
N I:GLY90 4.9 120.3 1.0
CE I:LYS88 4.9 117.5 1.0
CA I:CYS119 4.9 119.3 1.0
C I:CYS89 4.9 122.4 1.0
C I:CYS86 4.9 117.5 1.0
CA I:HIS91 5.0 116.6 1.0

Zinc binding site 7 out of 8 in 8p4b

Go back to Zinc Binding Sites List in 8p4b
Zinc binding site 7 out of 8 in the Structural Insights Into Human Co-Transcriptional Capping - Structure 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Structural Insights Into Human Co-Transcriptional Capping - Structure 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
J:Zn101

b:87.8
occ:1.00
 SG J:CYS7 2.3 60.4 1.0
SG J:CYS44 2.3 69.3 1.0
SG J:CYS45 2.3 67.3 1.0
N J:CYS45 2.5 67.3 1.0
CB J:CYS10 2.8 63.6 1.0
C J:CYS44 2.9 69.3 1.0
CA J:CYS45 2.9 67.3 1.0
CB J:CYS45 3.1 67.3 1.0
CB J:CYS44 3.1 69.3 1.0
CB J:CYS7 3.2 60.4 1.0
O J:CYS44 3.4 69.3 1.0
N J:CYS10 3.6 63.6 1.0
CA J:CYS44 3.6 69.3 1.0
CA J:CYS10 3.8 63.6 1.0
SG J:CYS10 4.1 63.6 1.0
C J:CYS45 4.4 67.3 1.0
N J:CYS44 4.5 69.3 1.0
CA J:CYS7 4.7 60.4 1.0
CB J:THR9 4.7 60.7 1.0
C J:THR9 4.8 60.7 1.0
N J:GLY11 4.8 61.5 1.0
C J:CYS10 4.9 63.6 1.0
NE J:ARG42 4.9 67.9 1.0

Zinc binding site 8 out of 8 in 8p4b

Go back to Zinc Binding Sites List in 8p4b
Zinc binding site 8 out of 8 in the Structural Insights Into Human Co-Transcriptional Capping - Structure 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 8 of Structural Insights Into Human Co-Transcriptional Capping - Structure 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
L:Zn101

b:147.1
occ:1.00
 SG L:CYS19 2.3 105.7 1.0
SG L:CYS22 2.3 107.7 1.0
SG L:CYS39 2.3 120.5 1.0
SG L:CYS36 2.3 116.3 1.0
CB L:CYS19 3.1 105.7 1.0
CB L:CYS36 3.3 116.3 1.0
O L:GLU38 3.5 123.8 1.0
CB L:CYS22 3.5 107.7 1.0
N L:CYS22 3.9 107.7 1.0
CB L:CYS39 4.0 120.5 1.0
CA L:CYS22 4.3 107.7 1.0
C L:GLU38 4.3 123.8 1.0
CB L:TYR41 4.4 106.6 1.0
CA L:CYS19 4.5 105.7 1.0
CA L:CYS36 4.7 116.3 1.0
C L:CYS22 4.8 107.7 1.0
OG1 L:THR24 4.9 107.5 1.0
N L:TYR41 4.9 106.6 1.0
CB L:GLU21 4.9 108.7 1.0
CA L:CYS39 4.9 120.5 1.0
CB L:THR24 4.9 107.5 1.0
N L:HIS23 4.9 105.2 1.0
N L:CYS39 5.0 120.5 1.0

Reference:

G.Garg, C.Dienemann, L.Farnung, J.Schwarz, A.Linden, H.Urlaub, P.Cramer. Structural Insights Into Human Co-Transcriptional Capping. Mol.Cell V. 83 2464 2023.
ISSN: ISSN 1097-2765
PubMed: 37369200
DOI: 10.1016/J.MOLCEL.2023.06.002
Page generated: Thu Dec 28 13:32:04 2023

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy