Zinc in PDB 8okx: Structure of Cgas in Complex with SPSB3-Elobc

Enzymatic activity of Structure of Cgas in Complex with SPSB3-Elobc

All present enzymatic activity of Structure of Cgas in Complex with SPSB3-Elobc:
2.7.7.86;

Zinc Binding Sites:

The binding sites of Zinc atom in the Structure of Cgas in Complex with SPSB3-Elobc (pdb code 8okx). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Cgas in Complex with SPSB3-Elobc, PDB code: 8okx:

Zinc binding site 1 out of 1 in 8okx

Go back to Zinc Binding Sites List in 8okx
Zinc binding site 1 out of 1 in the Structure of Cgas in Complex with SPSB3-Elobc


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Cgas in Complex with SPSB3-Elobc within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn601

b:77.5
occ:1.00
NE2 A:HIS390 2.1 56.7 1.0
SG A:CYS397 2.3 90.8 1.0
SG A:CYS396 2.3 91.7 1.0
SG A:CYS404 2.3 64.5 1.0
CD2 A:HIS390 2.9 56.7 1.0
CB A:CYS404 3.2 64.5 1.0
CE1 A:HIS390 3.2 56.7 1.0
CB A:CYS396 3.6 91.7 1.0
CB A:CYS397 3.9 90.8 1.0
N A:CYS404 4.0 64.5 1.0
C A:CYS396 4.1 91.7 1.0
CA A:CYS404 4.1 64.5 1.0
CG A:HIS390 4.1 56.7 1.0
N A:CYS397 4.1 90.8 1.0
ND1 A:HIS390 4.2 56.7 1.0
O A:CYS404 4.3 64.5 1.0
O A:CYS396 4.4 91.7 1.0
CA A:CYS396 4.4 91.7 1.0
C A:CYS404 4.5 64.5 1.0
CA A:CYS397 4.6 90.8 1.0
CA A:GLY391 4.7 56.7 1.0
N A:GLY391 4.9 56.7 1.0
NH2 A:ARG406 5.0 56.7 1.0
C A:LYS403 5.0 92.0 1.0

Reference:

P.B.Xu, A.Ablasser. Nuclear Degradation of Cgas Is Essential For Immune Homeostasis Nature 2024.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-024-07112-W
Page generated: Thu Oct 31 08:51:07 2024

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