Zinc in PDB 8okq: Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_2

All present enzymatic activity of Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_2:
4.2.1.1;

The structure of Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_2, PDB code: 8okq was solved by J.Brynda, P.M.Rezacova, E.Kudova, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.92 / 1.00
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.25, 41.27, 72.37, 90, 104.37, 90
R / Rfree (%)	16.8 / 17.9

The binding sites of Zinc atom in the Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_2 (pdb code 8okq). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_2, PDB code: 8okq:

Zinc binding site 1 out of 1 in the Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:10.0 occ:1.00 N19 A:VQC302 1.9 7.8 0.5 NE2 A:HIS94 2.0 10.5 1.0 NE2 A:HIS96 2.0 10.4 1.0 ND1 A:HIS119 2.0 9.7 1.0 CE1 A:HIS119 2.9 9.8 1.0 CD2 A:HIS94 3.0 10.4 1.0 CD2 A:HIS96 3.0 10.2 1.0 CE1 A:HIS94 3.0 10.4 1.0 CE1 A:HIS96 3.0 11.1 1.0 S22 A:VQC302 3.1 10.9 0.5 CG A:HIS119 3.1 9.4 1.0 O20 A:VQC302 3.3 12.0 0.5 CB A:HIS119 3.6 9.6 1.0 O25 A:VQC302 3.7 11.6 0.5 O A:HOH617 3.8 22.6 1.0 OG1 A:THR198 3.9 10.2 1.0 OE1 A:GLU106 4.0 10.0 1.0 NE2 A:HIS119 4.1 9.8 1.0 CG A:HIS94 4.1 11.1 1.0 ND1 A:HIS94 4.2 10.9 1.0 ND1 A:HIS96 4.2 11.2 1.0 CG A:HIS96 4.2 10.2 1.0 CD2 A:HIS119 4.2 9.7 1.0 O A:HOH605 4.3 24.0 1.0 O21 A:VQC302 4.3 12.7 0.5 CD A:GLU106 4.9 9.9 1.0

J.Brynda, P.M.Rezacova, E.Kudova. Carbonic Anhydrase in Complex with STERIOD_SULPHAMOYL To Be Published.