Zinc in PDB 8of4: Nucleosome Bound Human SIRT6 (Composite)

All present enzymatic activity of Nucleosome Bound Human SIRT6 (Composite):
2.3.1.286;

The binding sites of Zinc atom in the Nucleosome Bound Human SIRT6 (Composite) (pdb code 8of4). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Nucleosome Bound Human SIRT6 (Composite), PDB code: 8of4:

Zinc binding site 1 out of 1 in the Nucleosome Bound Human SIRT6 (Composite)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Nucleosome Bound Human SIRT6 (Composite) within 5.0Å range: probe atom residue distance (Å) B Occ L:Zn401 b:105.9 occ:1.00 SG L:CYS144 2.1 61.8 1.0 SG L:CYS177 2.1 71.1 1.0 SG L:CYS141 2.4 66.3 1.0 SG L:CYS166 2.9 72.9 1.0 CB L:CYS177 3.1 71.1 1.0 CB L:CYS141 3.5 66.3 1.0 CB L:CYS144 3.5 61.8 1.0 CB L:CYS166 3.9 72.9 1.0 N L:CYS144 4.1 61.8 1.0 CA L:CYS144 4.3 61.8 1.0 OG1 L:THR146 4.4 59.8 1.0 CA L:CYS177 4.5 71.1 1.0 C L:CYS144 4.7 61.8 1.0 CA L:CYS141 4.8 66.3 1.0 CG2 L:VAL168 4.9 70.1 1.0 CB L:VAL168 4.9 70.1 1.0 N L:GLY179 4.9 72.4 1.0 C L:LYS143 4.9 65.6 1.0 CB L:LYS143 4.9 65.6 1.0 CA L:GLY179 4.9 72.4 1.0 CB L:THR146 5.0 59.8 1.0 C L:CYS177 5.0 71.1 1.0

E.Smirnova, E.Bignon, P.Schultz, G.Papai, A.Ben-Shem. Binding to Nucleosome Poises SIRT6 For Histone H3 De-Acetylation Elife 2023.
ISSN: ESSN 2050-084X
DOI: 10.7554/ELIFE.87989.1