Zinc in PDB 8ehn: Prrsv-1 PLP2 Domain

The structure of Prrsv-1 PLP2 Domain, PDB code: 8ehn was solved by B.A.Bailey-Elkin, B.L.Mark, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.58 / 2.30
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	67.499, 102.347, 100.739, 90, 90, 90
R / Rfree (%)	20 / 25.3

The binding sites of Zinc atom in the Prrsv-1 PLP2 Domain (pdb code 8ehn). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Prrsv-1 PLP2 Domain, PDB code: 8ehn:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Prrsv-1 PLP2 Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Prrsv-1 PLP2 Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn601 b:78.6 occ:1.00 SG A:CYS521 2.3 74.8 1.0 SG A:CYS516 2.3 73.8 1.0 SG A:CYS485 2.3 82.1 1.0 SG A:CYS525 2.4 98.6 1.0 CB A:CYS521 3.2 77.6 1.0 CB A:CYS485 3.3 66.9 1.0 CB A:CYS516 3.3 73.7 1.0 CB A:CYS525 3.4 96.0 1.0 CA A:CYS516 3.9 77.3 1.0 CA A:CYS485 3.9 71.4 1.0 CD A:PRO486 4.2 79.7 1.0 NH2 A:ARG483 4.3 117.1 1.0 ND2 A:ASN487 4.5 101.5 1.0 C A:CYS485 4.6 82.9 1.0 CA A:CYS521 4.7 83.8 1.0 N A:PRO486 4.7 77.8 1.0 N A:CYS516 4.8 80.2 1.0 CB A:ASN487 4.8 78.5 1.0 CA A:CYS525 4.8 102.6 1.0 N A:ASN487 4.9 76.0 1.0

Zinc binding site 2 out of 2 in the Prrsv-1 PLP2 Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Prrsv-1 PLP2 Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn601 b:89.2 occ:1.00 SG B:CYS516 2.3 89.4 1.0 SG B:CYS521 2.3 91.5 1.0 SG B:CYS485 2.3 88.8 1.0 SG B:CYS525 2.4 96.8 1.0 CB B:CYS521 3.1 101.6 1.0 CB B:CYS516 3.3 78.7 1.0 CB B:CYS485 3.4 92.7 1.0 CB B:CYS525 3.4 101.1 1.0 CA B:CYS516 3.9 82.5 1.0 CA B:CYS485 4.1 82.6 1.0 CD B:PRO486 4.2 87.5 1.0 NH2 B:ARG483 4.5 127.1 1.0 ND2 B:ASN487 4.6 98.3 1.0 CA B:CYS521 4.7 109.1 1.0 C B:CYS485 4.7 87.9 1.0 N B:PRO486 4.8 85.3 1.0 N B:CYS516 4.8 81.9 1.0 CA B:CYS525 4.8 120.4 1.0 CB B:ASN487 4.8 69.2 1.0 N B:ASN487 4.9 80.0 1.0

B.A.Bailey-Elkin, R.C.M.Knaap, A.De Silva, I.M.Boekhoud, S.Mous, N.Van Vught, M.Khajehpour, E.Van Den Born, M.Kikkert, B.L.Mark. Demonstrating the Importance of Porcine Reproductive and Respiratory Syndrome Virus Papain-Like Protease 2 Deubiquitinating Activity in Viral Replication By Structure-Guided Mutagenesis Plos Pathog. 2023.
ISSN: ESSN 1553-7374