Zinc in PDB 8aqs: Ba.4/5 Sars-Cov-2 Spike Bound to Human ACE2 (Local)

All present enzymatic activity of Ba.4/5 Sars-Cov-2 Spike Bound to Human ACE2 (Local):
3.4.17.23;

The binding sites of Zinc atom in the Ba.4/5 Sars-Cov-2 Spike Bound to Human ACE2 (Local) (pdb code 8aqs). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Ba.4/5 Sars-Cov-2 Spike Bound to Human ACE2 (Local), PDB code: 8aqs:

Zinc binding site 1 out of 1 in the Ba.4/5 Sars-Cov-2 Spike Bound to Human ACE2 (Local)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Ba.4/5 Sars-Cov-2 Spike Bound to Human ACE2 (Local) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn906 b:104.9 occ:1.00 NE2 B:HIS374 2.3 57.4 1.0 NE2 B:HIS378 2.3 58.9 1.0 OE2 B:GLU402 2.4 75.0 1.0 CD2 B:HIS378 3.1 53.4 1.0 CD2 B:HIS374 3.1 58.1 1.0 CD B:GLU402 3.3 76.4 1.0 CE1 B:HIS374 3.3 53.7 1.0 CE1 B:HIS378 3.4 55.4 1.0 OE1 B:GLU402 3.7 77.0 1.0 CG B:HIS374 4.2 49.5 1.0 CG B:HIS378 4.3 45.0 1.0 ND1 B:HIS374 4.3 53.9 1.0 CG B:GLU402 4.4 66.5 1.0 ND1 B:HIS378 4.4 53.3 1.0 OE2 B:GLU375 4.6 65.2 1.0

C.N.Dong, L.Kelvin, T.Priscilla, B.Bertrand, N.Sergey, M.Alexander, T.Didier, S.Henning, P.Florence. Cryo-Em Structures and Binding of Mouse and Human ACE2 to Sars-Cov-2 Variants of Concern Indicate That Mutations Enabling Immune Escape Could Expand Host Range To Be Published 2023.
DOI: 10.1371/JOURNAL.PPAT.1011206