Zinc in PDB 8abz: Rna Polymerase at U-Rich Pause Bound to Non-Regulatory Rna - Pause Prone, Closed Clamp State

All present enzymatic activity of Rna Polymerase at U-Rich Pause Bound to Non-Regulatory Rna - Pause Prone, Closed Clamp State:
2.7.7.6;

The structure of Rna Polymerase at U-Rich Pause Bound to Non-Regulatory Rna - Pause Prone, Closed Clamp State also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Rna Polymerase at U-Rich Pause Bound to Non-Regulatory Rna - Pause Prone, Closed Clamp State (pdb code 8abz). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Rna Polymerase at U-Rich Pause Bound to Non-Regulatory Rna - Pause Prone, Closed Clamp State, PDB code: 8abz:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Rna Polymerase at U-Rich Pause Bound to Non-Regulatory Rna - Pause Prone, Closed Clamp State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Rna Polymerase at U-Rich Pause Bound to Non-Regulatory Rna - Pause Prone, Closed Clamp State within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1502 b:130.7 occ:1.00 SG D:CYS88 2.3 80.5 1.0 SG D:CYS85 2.3 79.1 1.0 SG D:CYS72 2.3 75.8 1.0 SG D:CYS70 2.3 77.7 1.0 CB D:CYS70 3.0 77.7 1.0 CB D:CYS85 3.1 79.1 1.0 CB D:CYS88 3.1 80.5 1.0 N D:CYS88 3.7 80.5 1.0 N D:CYS72 3.8 75.8 1.0 CB D:CYS72 3.8 75.8 1.0 N D:LYS74 3.9 81.5 1.0 CB D:LYS74 3.9 81.5 1.0 CA D:CYS88 4.0 80.5 1.0 N D:GLY73 4.1 72.1 1.0 CA D:CYS72 4.2 75.8 1.0 CA D:CYS70 4.3 77.7 1.0 N D:LEU71 4.3 66.1 1.0 N D:TYR75 4.4 88.3 1.0 C D:CYS72 4.4 75.8 1.0 C D:CYS70 4.4 77.7 1.0 CA D:LYS74 4.5 81.5 1.0 CA D:CYS85 4.5 79.1 1.0 C D:LYS87 4.7 85.5 1.0 CB D:LYS87 4.7 85.5 1.0 C D:CYS85 4.8 79.1 1.0 C D:GLY73 4.9 72.1 1.0 C D:LEU71 4.9 66.1 1.0 N D:LYS87 4.9 85.5 1.0 C D:CYS88 5.0 80.5 1.0 C D:LYS74 5.0 81.5 1.0

Zinc binding site 2 out of 2 in the Rna Polymerase at U-Rich Pause Bound to Non-Regulatory Rna - Pause Prone, Closed Clamp State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Rna Polymerase at U-Rich Pause Bound to Non-Regulatory Rna - Pause Prone, Closed Clamp State within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1503 b:60.6 occ:1.00 SG D:CYS895 2.3 26.3 1.0 SG D:CYS898 2.3 27.9 1.0 SG D:CYS888 2.3 39.0 1.0 SG D:CYS814 2.3 42.7 1.0 CB D:CYS814 2.9 42.7 1.0 CB D:CYS898 3.3 27.9 1.0 CB D:CYS888 3.3 39.0 1.0 CB D:CYS895 3.7 26.3 1.0 CA D:CYS888 3.8 39.0 1.0 N D:CYS814 4.1 42.7 1.0 CA D:CYS814 4.1 42.7 1.0 OG1 D:THR890 4.3 40.6 1.0 OG1 D:THR816 4.3 52.0 1.0 N D:CYS895 4.3 26.3 1.0 N D:CYS898 4.4 27.9 1.0 N D:ASP889 4.4 49.6 1.0 CA D:CYS898 4.4 27.9 1.0 CA D:CYS895 4.6 26.3 1.0 C D:CYS888 4.6 39.0 1.0 N D:CYS888 5.0 39.0 1.0 C D:CYS814 5.0 42.7 1.0

S.Dey, C.Batisse, J.Shukla, M.W.Webster, M.Takacs, C.Saint-Andre, A.Weixlbaumer. Structural Insights Into Rna-Mediated Transcription Regulation in Bacteria. Mol.Cell V. 82 3885 2022.
ISSN: ISSN 1097-2765
PubMed: 36220101
DOI: 10.1016/J.MOLCEL.2022.09.020