Zinc in PDB 7z8r: CAND1-CUL1-RBX1

The binding sites of Zinc atom in the CAND1-CUL1-RBX1 (pdb code 7z8r). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the CAND1-CUL1-RBX1, PDB code: 7z8r:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the CAND1-CUL1-RBX1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of CAND1-CUL1-RBX1 within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn201 b:86.5 occ:1.00 ND1 R:HIS80 2.0 74.7 1.0 SG R:CYS45 2.3 84.8 1.0 SG R:CYS42 2.3 81.6 1.0 SG R:CYS83 2.3 73.5 1.0 CB R:CYS42 2.8 81.6 1.0 CE1 R:HIS80 2.8 74.7 1.0 CG R:HIS80 3.1 74.7 1.0 CB R:CYS45 3.5 84.8 1.0 CB R:CYS83 3.5 73.5 1.0 CB R:HIS80 3.6 74.7 1.0 N R:CYS45 3.9 84.8 1.0 NE2 R:HIS80 4.0 74.7 1.0 CD2 R:HIS80 4.2 74.7 1.0 O R:CYS45 4.2 84.8 1.0 CA R:CYS45 4.2 84.8 1.0 N R:HIS80 4.3 74.7 1.0 CA R:CYS42 4.3 81.6 1.0 CA R:HIS80 4.6 74.7 1.0 C R:CYS45 4.6 84.8 1.0 CB R:CYS53 4.9 88.8 1.0 CA R:CYS83 4.9 73.5 1.0 CB R:ILE44 5.0 79.7 1.0 C R:CYS42 5.0 81.6 1.0

Zinc binding site 2 out of 3 in the CAND1-CUL1-RBX1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of CAND1-CUL1-RBX1 within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn202 b:73.1 occ:1.00 OD2 R:ASP97 2.0 71.2 1.0 ND1 R:HIS77 2.0 62.6 1.0 SG R:CYS75 2.3 60.6 1.0 SG R:CYS94 2.3 68.9 1.0 CG R:ASP97 2.8 71.2 1.0 CE1 R:HIS77 2.9 62.6 1.0 CG R:HIS77 3.1 62.6 1.0 CB R:CYS75 3.3 60.6 1.0 CB R:CYS94 3.5 68.9 1.0 CB R:ASP97 3.5 71.2 1.0 OD1 R:ASP97 3.6 71.2 1.0 CB R:HIS77 3.6 62.6 1.0 NE2 R:HIS77 4.0 62.6 1.0 CD2 R:HIS77 4.2 62.6 1.0 N R:ASP97 4.3 71.2 1.0 CA R:ASP97 4.6 71.2 1.0 CA R:CYS75 4.6 60.6 1.0 O R:CYS75 4.7 60.6 1.0 CZ3 R:TRP101 4.7 65.3 1.0 C R:LEU96 4.7 68.1 1.0 C R:CYS75 4.8 60.6 1.0 CB R:LEU96 4.8 68.1 1.0 CA R:HIS77 4.9 62.6 1.0 CA R:CYS94 4.9 68.9 1.0 CE3 R:TRP101 4.9 65.3 1.0 N R:HIS77 4.9 62.6 1.0

Zinc binding site 3 out of 3 in the CAND1-CUL1-RBX1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of CAND1-CUL1-RBX1 within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn203 b:94.5 occ:1.00 ND1 R:HIS82 2.0 76.2 1.0 SG R:CYS68 2.3 85.0 1.0 SG R:CYS56 2.3 94.1 1.0 SG R:CYS53 2.3 88.8 1.0 CE1 R:HIS82 2.6 76.2 1.0 CB R:CYS56 2.9 94.1 1.0 CG R:HIS82 3.3 76.2 1.0 NE2 R:HIS82 3.8 76.2 1.0 CB R:CYS68 3.9 85.0 1.0 CB R:HIS82 4.0 76.2 1.0 CB R:CYS53 4.1 88.8 1.0 CD2 R:HIS82 4.2 76.2 1.0 CA R:CYS56 4.2 94.1 1.0 CD1 R:LEU52 4.4 90.2 1.0 N R:CYS56 4.4 94.1 1.0 O R:GLU67 4.6 86.3 1.0 CA R:CYS68 4.7 85.0 1.0 N R:CYS53 4.8 88.8 1.0 O R:THR64 5.0 88.6 1.0 CA R:CYS53 5.0 88.8 1.0

K.Baek, D.C.Scott, L.T.Henneberg, M.T.King, M.Mann, B.A.Schulman. Systemwide Disassembly and Assembly of Scf Ubiquitin Ligase Complexes. Cell 2023.
ISSN: ISSN 1097-4172
PubMed: 37028429
DOI: 10.1016/J.CELL.2023.02.035