Zinc in PDB 7z7e: Crystal Structure of P63 Dna Binding Domain in Complex with Inhibitory Darpin G4

The structure of Crystal Structure of P63 Dna Binding Domain in Complex with Inhibitory Darpin G4, PDB code: 7z7e was solved by A.Strubel, J.Gebel, A.Chaikuad, P.Muenick, V.Doetsch, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.29 / 1.80
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	96.578, 96.578, 77.071, 90, 90, 120
R / Rfree (%)	19.7 / 24.9

The binding sites of Zinc atom in the Crystal Structure of P63 Dna Binding Domain in Complex with Inhibitory Darpin G4 (pdb code 7z7e). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of P63 Dna Binding Domain in Complex with Inhibitory Darpin G4, PDB code: 7z7e:

Zinc binding site 1 out of 1 in the Crystal Structure of P63 Dna Binding Domain in Complex with Inhibitory Darpin G4


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of P63 Dna Binding Domain in Complex with Inhibitory Darpin G4 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:32.5 occ:1.00 HD1 A:HIS209 1.2 31.8 0.0 HG A:CYS274 1.4 32.6 0.0 ND1 A:HIS209 2.1 31.9 1.0 SG A:CYS270 2.3 35.1 1.0 SG A:CYS274 2.3 32.6 1.0 SG A:CYS206 2.3 31.6 1.0 HG A:CYS206 2.5 31.6 0.0 HG A:CYS270 2.7 35.1 0.0 HB2 A:HIS209 2.8 32.0 1.0 HB3 A:CYS274 2.9 32.5 1.0 CE1 A:HIS209 3.0 36.4 1.0 CB A:CYS274 3.1 32.2 1.0 CG A:HIS209 3.1 34.2 1.0 H A:CYS206 3.1 31.3 1.0 HE1 A:HIS209 3.2 35.8 1.0 HB3 A:CYS270 3.2 32.4 1.0 CB A:CYS270 3.3 32.3 1.0 HA A:CYS270 3.3 30.2 1.0 HB3 A:CYS206 3.4 32.3 1.0 HE1 B:HIS35 3.4 68.6 1.0 HB2 A:CYS274 3.4 32.5 1.0 CB A:HIS209 3.5 32.1 1.0 CB A:CYS206 3.5 33.3 1.0 HE2 B:HIS35 3.6 64.7 0.0 CA A:CYS270 3.8 30.1 1.0 H A:HIS209 3.8 33.0 1.0 H A:ASN271 3.9 31.4 1.0 N A:CYS206 3.9 32.6 1.0 CE1 B:HIS35 4.0 70.9 1.0 HB3 A:HIS209 4.0 32.0 1.0 NE2 B:HIS35 4.1 64.8 1.0 HB2 A:CYS270 4.1 32.4 1.0 NE2 A:HIS209 4.2 38.6 1.0 CD2 A:HIS209 4.2 38.8 1.0 CA A:CYS206 4.3 30.6 1.0 HB2 A:CYS206 4.3 32.3 1.0 HB3 A:ARG205 4.5 29.6 1.0 N A:HIS209 4.5 32.7 1.0 CA A:CYS274 4.5 33.1 1.0 N A:ASN271 4.5 31.0 1.0 HA A:CYS274 4.5 33.1 1.0 O A:HOH584 4.6 31.5 1.0 HD22 A:ASN208 4.6 57.8 1.0 CA A:HIS209 4.6 29.8 1.0 HB3 A:ASN208 4.6 40.8 1.0 C A:CYS270 4.7 29.9 1.0 HA A:ARG205 4.7 29.3 1.0 O A:MET269 4.7 29.4 1.0 HD12 A:ILE167 4.8 31.0 1.0 O A:CYS206 4.9 30.7 1.0 C A:CYS206 4.9 32.1 1.0 HE2 A:HIS209 5.0 38.6 0.0 N A:CYS270 5.0 28.5 1.0

A.Strubel, P.Munick, A.Chaikuad, B.Dreier, J.Schaefer, J.Gebel, C.Osterburg, M.Tuppi, B.Schafer, S.Knapp, A.Pluckthun, V.Dotsch. Designed Ankyrin Repeat Proteins As A Tool Box For Analyzing P63. Cell Death Differ. V. 29 2445 2022.
ISSN: ISSN 1350-9047
PubMed: 35717504
DOI: 10.1038/S41418-022-01030-Y