Zinc in PDB 8x1n: Cryo-Em Structure of Human Alpha-Fetoprotein

The binding sites of Zinc atom in the Cryo-Em Structure of Human Alpha-Fetoprotein (pdb code 8x1n). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of Human Alpha-Fetoprotein, PDB code: 8x1n:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of Human Alpha-Fetoprotein


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Human Alpha-Fetoprotein within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn701 b:71.1 occ:1.00 NE2 A:HIS268 2.3 34.5 1.0 NE2 A:HIS264 2.3 36.2 1.0 NE2 A:HIS22 2.4 64.8 1.0 OD2 A:ASP280 2.4 42.6 1.0 CD2 A:HIS268 2.8 32.7 1.0 CD2 A:HIS22 3.1 65.2 1.0 CD2 A:HIS264 3.2 33.4 1.0 CE1 A:HIS268 3.3 35.4 1.0 CE1 A:HIS22 3.4 67.6 1.0 CE1 A:HIS264 3.4 31.6 1.0 CG A:ASP280 3.6 36.9 1.0 CG A:HIS268 3.9 27.5 1.0 OD1 A:ASP280 4.0 36.6 1.0 ND1 A:HIS268 4.2 30.1 1.0 CG A:HIS22 4.2 65.9 1.0 ND1 A:HIS22 4.3 66.3 1.0 CG A:HIS264 4.4 26.2 1.0 OD2 A:ASP276 4.4 51.1 1.0 ND1 A:HIS264 4.5 27.6 1.0 CD1 A:LEU32 4.7 47.1 1.0 CB A:ASP276 4.8 35.6 1.0 CB A:ASP280 4.8 28.3 1.0 CG A:ASP276 4.9 44.5 1.0

K.Liu, C.Wu, M.Zhu, J.Xu, B.Lin, H.Lin, Z.Liu, M.Li. Structural Characteristics of Alpha-Fetoprotein, Including N-Glycosylation, Metal Ion and Fatty Acid Binding Sites. Commun Biol V. 7 505 2024.
ISSN: ESSN 2399-3642
PubMed: 38678117
DOI: 10.1038/S42003-024-06219-0