Zinc in PDB 7z36: Crystal Structure of the KAP1 Tripartite Motif in Complex with the ZNF93 Krab Domain

Enzymatic activity of Crystal Structure of the KAP1 Tripartite Motif in Complex with the ZNF93 Krab Domain

Protein crystallography data

Zinc Binding Sites:

Zinc binding site 1 out of 8 in 7z36

Zinc Binding Sites List in 7z36

Zinc binding site 1 out of 8 in the Crystal Structure of the KAP1 Tripartite Motif in Complex with the ZNF93 Krab Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the KAP1 Tripartite Motif in Complex with the ZNF93 Krab Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:66.3 occ:1.00 ND1 A:HIS216 2.3 41.4 1.0 SG A:CYS251 2.3 81.6 1.0 SG A:CYS214 2.3 70.6 1.0 SG A:CYS248 2.3 70.7 1.0 HB2 A:HIS216 2.7 74.7 1.0 HB2 A:CYS251 2.9 85.3 1.0 CB A:CYS251 3.1 71.1 1.0 CG A:HIS216 3.2 62.8 1.0 CB A:CYS248 3.2 74.4 1.0 HB2 A:CYS248 3.2 89.3 1.0 H A:CYS251 3.2 75.8 1.0 HB3 A:CYS248 3.3 89.3 1.0 CE1 A:HIS216 3.3 46.2 1.0 HB2 A:CYS214 3.4 56.3 1.0 CB A:HIS216 3.4 62.2 1.0 HE1 A:HIS216 3.5 55.5 1.0 CB A:CYS214 3.5 47.0 1.0 HB A:VAL250 3.7 59.2 1.0 N A:CYS251 3.8 63.1 1.0 HB3 A:HIS216 3.8 74.7 1.0 HB3 A:CYS251 3.9 85.3 1.0 H A:HIS216 4.0 59.9 1.0 HB3 A:CYS214 4.0 56.3 1.0 CA A:CYS251 4.1 61.9 1.0 O A:CYS214 4.1 70.2 1.0 CD2 A:HIS216 4.3 57.8 1.0 NE2 A:HIS216 4.4 52.5 1.0 H A:VAL250 4.4 79.2 1.0 C A:CYS214 4.6 55.1 1.0 HB2 A:GLN253 4.6 82.0 1.0 N A:HIS216 4.6 49.9 1.0 HA A:CYS251 4.6 74.3 1.0 CA A:HIS216 4.6 51.5 1.0 HD22 A:LEU212 4.6 88.1 1.0 CA A:CYS214 4.6 56.7 1.0 CB A:VAL250 4.6 49.4 1.0 HG12 A:VAL250 4.7 57.7 1.0 H A:GLN253 4.7 75.6 1.0 CA A:CYS248 4.7 78.8 1.0 HB2 A:LEU212 4.7 76.4 1.0 HD23 A:LEU212 4.8 88.1 1.0 H A:CYS214 4.8 68.1 1.0 C A:VAL250 4.9 64.0 1.0 HB3 A:LEU212 5.0 76.4 1.0

Zinc binding site 2 out of 8 in 7z36

Zinc Binding Sites List in 7z36

Zinc binding site 2 out of 8 in the Crystal Structure of the KAP1 Tripartite Motif in Complex with the ZNF93 Krab Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the KAP1 Tripartite Motif in Complex with the ZNF93 Krab Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn502 b:77.6 occ:1.00 SG A:CYS196 2.2 78.6 1.0 SG A:CYS219 2.3 62.7 1.0 SG A:CYS199 2.3 74.5 1.0 SG A:CYS222 2.4 79.7 1.0 HB2 A:CYS219 2.9 78.6 1.0 HB2 A:CYS196 3.1 65.7 1.0 CB A:CYS196 3.1 54.7 1.0 HB3 A:CYS196 3.2 65.7 1.0 HB3 A:CYS199 3.2 87.7 1.0 CB A:CYS219 3.2 65.5 1.0 H A:CYS219 3.2 87.6 1.0 H A:CYS199 3.3 67.0 1.0 CB A:CYS199 3.4 73.1 1.0 HG13 A:VAL198 3.6 79.8 1.0 HG12 A:VAL198 3.8 79.8 1.0 HB2 A:CYS222 3.8 89.8 1.0 CB A:CYS222 3.9 74.8 1.0 HB3 A:CYS219 3.9 78.6 1.0 N A:CYS219 4.0 73.0 1.0 N A:CYS199 4.0 55.8 1.0 CG1 A:VAL198 4.1 66.5 1.0 HB2 A:CYS199 4.1 87.7 1.0 CA A:CYS219 4.2 75.4 1.0 CA A:CYS199 4.3 66.4 1.0 HB3 A:CYS222 4.3 89.8 1.0 HB2 A:GLU201 4.4 83.0 1.0 HH21 A:ARG207 4.4 124.1 1.0 HG11 A:VAL198 4.5 79.8 1.0 H A:VAL198 4.5 64.4 1.0 H A:GLU201 4.5 70.1 1.0 CA A:CYS196 4.6 49.6 1.0 HB1 A:ALA218 4.7 54.8 1.0 H A:CYS222 4.8 99.5 1.0 H A:ARG200 4.8 77.8 1.0 HA A:CYS219 4.9 90.5 1.0 HA A:ALA218 4.9 68.9 1.0 HB3 A:ALA221 4.9 97.7 1.0 HA A:CYS196 4.9 59.5 1.0 NH2 A:ARG207 4.9 103.4 1.0

Zinc binding site 3 out of 8 in 7z36

Zinc Binding Sites List in 7z36

Zinc binding site 3 out of 8 in the Crystal Structure of the KAP1 Tripartite Motif in Complex with the ZNF93 Krab Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of the KAP1 Tripartite Motif in Complex with the ZNF93 Krab Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn503 b:138.0 occ:1.00 HG A:CYS278 1.4 157.9 1.0 SG A:CYS298 2.3 105.3 1.0 SG A:CYS278 2.3 131.6 1.0 SG A:CYS301 2.3 120.8 1.0 ND1 A:HIS281 2.4 116.3 1.0 HB A:VAL280 2.7 162.9 1.0 HB2 A:HIS281 3.0 156.8 1.0 H A:HIS281 3.1 169.9 1.0 CG A:HIS281 3.3 122.6 1.0 CE1 A:HIS281 3.3 120.7 1.0 HB2 A:CYS301 3.4 131.9 1.0 H A:CYS301 3.5 128.2 1.0 HE1 A:HIS281 3.5 144.9 1.0 CB A:CYS301 3.5 109.9 1.0 CB A:HIS281 3.6 130.7 1.0 CB A:VAL280 3.6 135.8 1.0 N A:HIS281 3.6 141.6 1.0 HB3 A:CYS298 3.6 130.2 1.0 CB A:CYS298 3.7 108.5 1.0 HG12 A:VAL280 3.7 139.6 1.0 H A:CYS298 3.8 121.3 1.0 H A:VAL280 4.0 159.7 1.0 CB A:CYS278 4.0 123.5 1.0 N A:CYS301 4.0 106.8 1.0 HB2 A:ASP300 4.1 142.2 1.0 CG1 A:VAL280 4.1 116.3 1.0 HB2 A:CYS278 4.1 148.1 1.0 HB3 A:CYS278 4.2 148.1 1.0 HB2 A:GLU284 4.2 177.2 1.0 CA A:HIS281 4.2 139.1 1.0 HG11 A:VAL280 4.3 139.6 1.0 HB3 A:CYS301 4.3 131.9 1.0 CA A:CYS301 4.3 105.3 1.0 C A:VAL280 4.3 133.8 1.0 HB2 A:CYS298 4.3 130.2 1.0 CA A:VAL280 4.4 135.3 1.0 HB3 A:HIS281 4.4 156.8 1.0 NE2 A:HIS281 4.4 132.3 1.0 CD2 A:HIS281 4.4 125.0 1.0 HG3 A:GLU284 4.4 217.0 1.0 HG21 A:VAL280 4.5 145.6 1.0 CG2 A:VAL280 4.5 121.3 1.0 HG23 A:VAL280 4.5 145.6 1.0 HA A:CYS301 4.5 126.3 1.0 N A:CYS298 4.6 101.1 1.0 N A:VAL280 4.6 133.0 1.0 CA A:CYS298 4.7 109.0 1.0 HB3 A:GLU284 4.7 177.2 1.0 CB A:GLU284 4.9 147.7 1.0 HA A:HIS281 4.9 166.9 1.0 HD23 A:LEU286 4.9 132.1 1.0 H A:ASP300 4.9 123.7 1.0 CB A:ASP300 4.9 118.5 1.0 C A:ASP300 4.9 113.5 1.0

Zinc binding site 4 out of 8 in 7z36

Zinc Binding Sites List in 7z36

Zinc binding site 4 out of 8 in the Crystal Structure of the KAP1 Tripartite Motif in Complex with the ZNF93 Krab Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of the KAP1 Tripartite Motif in Complex with the ZNF93 Krab Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn504 b:132.9 occ:1.00 SG A:CYS293 2.3 140.0 1.0 SG A:CYS290 2.3 97.5 1.0 ND1 A:HIS306 2.3 116.6 1.0 ND1 A:HIS309 2.4 119.7 1.0 HB3 A:HIS306 2.6 144.7 1.0 CG A:HIS306 2.9 126.3 1.0 CE1 A:HIS309 3.2 118.3 1.0 HE1 A:HIS309 3.2 141.9 1.0 CE1 A:HIS306 3.2 115.0 1.0 CB A:HIS306 3.2 120.6 1.0 HB2 A:CYS293 3.4 148.3 1.0 HB3 A:SER292 3.5 142.4 1.0 CG A:HIS309 3.5 117.7 1.0 CB A:CYS293 3.5 123.6 1.0 HE1 A:HIS306 3.5 137.9 1.0 HB2 A:HIS309 3.6 129.1 1.0 HE22 A:GLN302 3.8 126.0 1.0 CD2 A:HIS306 3.9 111.5 1.0 HB2 A:HIS306 3.9 144.7 1.0 CB A:HIS309 4.0 107.6 1.0 HA A:HIS306 4.0 135.4 1.0 NE2 A:HIS306 4.0 107.7 1.0 H A:CYS293 4.0 144.2 1.0 CB A:CYS290 4.0 107.3 1.0 HB3 A:HIS309 4.0 129.1 1.0 HB3 A:CYS293 4.2 148.3 1.0 HB3 A:CYS290 4.2 128.7 1.0 CA A:HIS306 4.2 112.8 1.0 HB2 A:CYS290 4.3 128.7 1.0 N A:CYS293 4.3 120.2 1.0 NE2 A:HIS309 4.3 127.2 1.0 CB A:SER292 4.4 118.7 1.0 HG A:SER292 4.4 129.7 1.0 CA A:CYS293 4.5 118.8 1.0 OG A:SER292 4.5 108.1 1.0 CD2 A:HIS309 4.5 121.6 1.0 NE2 A:GLN302 4.6 105.0 1.0 HD2 A:HIS306 4.6 133.7 1.0 HE2 A:HIS306 4.7 129.2 1.0 O A:HIS306 4.8 119.8 1.0 C A:SER292 4.9 120.6 1.0 HA A:CYS293 4.9 142.5 1.0 HB2 A:SER292 5.0 142.4 1.0

Zinc binding site 5 out of 8 in 7z36

Zinc Binding Sites List in 7z36

Zinc binding site 5 out of 8 in the Crystal Structure of the KAP1 Tripartite Motif in Complex with the ZNF93 Krab Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Crystal Structure of the KAP1 Tripartite Motif in Complex with the ZNF93 Krab Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn501 b:40.0 occ:1.00 ND1 B:HIS216 2.2 33.2 1.0 SG B:CYS214 2.3 33.9 1.0 SG B:CYS248 2.3 41.4 1.0 SG B:CYS251 2.3 41.0 1.0 O B:VAL250 2.5 78.4 1.0 HB2 B:HIS216 2.8 44.2 1.0 HB3 B:CYS248 3.2 58.3 1.0 CG B:HIS216 3.2 50.1 1.0 CE1 B:HIS216 3.2 33.6 1.0 HB2 B:CYS214 3.2 47.2 1.0 CB B:CYS248 3.2 48.5 1.0 HB2 B:CYS248 3.4 58.3 1.0 HE1 B:HIS216 3.4 40.3 1.0 CB B:CYS214 3.4 39.3 1.0 CB B:HIS216 3.5 36.8 1.0 HB3 B:CYS251 3.8 42.6 1.0 HB B:VAL250 3.8 54.9 1.0 C B:VAL250 3.8 66.6 1.0 CB B:CYS251 3.8 35.5 1.0 H B:HIS216 3.9 41.4 1.0 HB3 B:CYS214 3.9 47.2 1.0 HB3 B:HIS216 4.0 44.2 1.0 HB3 B:GLN253 4.1 40.2 1.0 H B:GLN253 4.2 53.1 1.0 NE2 B:HIS216 4.3 37.0 1.0 CD2 B:HIS216 4.3 39.5 1.0 H B:VAL250 4.4 51.3 1.0 O B:CYS214 4.4 29.0 1.0 HD22 B:LEU212 4.5 46.1 1.0 HB2 B:CYS251 4.5 42.6 1.0 N B:HIS216 4.5 34.5 1.0 CA B:HIS216 4.6 36.5 1.0 CB B:VAL250 4.6 45.8 1.0 HB2 B:GLN253 4.6 40.2 1.0 CA B:CYS214 4.6 27.8 1.0 C B:CYS214 4.6 35.9 1.0 HG12 B:VAL250 4.6 50.3 1.0 CA B:CYS251 4.7 43.7 1.0 N B:CYS251 4.7 36.2 1.0 CA B:VAL250 4.7 48.0 1.0 CA B:CYS248 4.7 55.7 1.0 HD23 B:LEU212 4.8 46.1 1.0 CB B:GLN253 4.8 33.5 1.0 HB2 B:LEU212 4.8 38.0 1.0 H B:CYS214 4.8 45.6 1.0 H B:LYS252 4.8 46.0 1.0 N B:VAL250 4.9 42.8 1.0 HA B:CYS248 5.0 66.9 1.0 C B:CYS251 5.0 34.9 1.0

Zinc binding site 6 out of 8 in 7z36

Zinc Binding Sites List in 7z36

Zinc binding site 6 out of 8 in the Crystal Structure of the KAP1 Tripartite Motif in Complex with the ZNF93 Krab Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Crystal Structure of the KAP1 Tripartite Motif in Complex with the ZNF93 Krab Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn502 b:39.2 occ:1.00 SG B:CYS196 2.3 46.2 1.0 SG B:CYS219 2.3 45.8 1.0 SG B:CYS222 2.3 41.5 1.0 SG B:CYS199 2.3 46.0 1.0 HB2 B:CYS219 2.8 50.2 1.0 HB3 B:CYS196 3.0 48.2 1.0 HB2 B:CYS196 3.0 48.2 1.0 CB B:CYS196 3.0 40.2 1.0 CB B:CYS219 3.1 41.9 1.0 H B:CYS219 3.2 51.3 1.0 H B:CYS199 3.3 53.0 1.0 HB3 B:CYS199 3.3 56.0 1.0 HH21 B:ARG207 3.4 65.9 1.0 CB B:CYS199 3.4 46.7 1.0 HB2 B:CYS222 3.5 58.2 1.0 CB B:CYS222 3.6 48.5 1.0 HB B:VAL198 3.8 52.5 1.0 HB3 B:CYS219 3.8 50.2 1.0 N B:CYS199 4.0 44.1 1.0 N B:CYS219 4.0 42.8 1.0 HB3 B:CYS222 4.0 58.2 1.0 HB2 B:GLU201 4.1 71.0 1.0 NH2 B:ARG207 4.1 54.9 1.0 CA B:CYS219 4.2 38.4 1.0 HB2 B:CYS199 4.2 56.0 1.0 CA B:CYS199 4.3 44.7 1.0 H B:GLU201 4.3 53.5 1.0 HH22 B:ARG207 4.4 65.9 1.0 H B:VAL198 4.4 48.0 1.0 CA B:CYS196 4.5 46.9 1.0 HE B:ARG207 4.5 71.0 1.0 HB1 B:ALA218 4.6 57.1 1.0 H B:CYS222 4.7 71.5 1.0 H B:ARG200 4.8 57.5 1.0 CB B:VAL198 4.8 43.7 1.0 HA B:CYS219 4.8 46.1 1.0 HA B:CYS196 4.9 56.3 1.0 CA B:CYS222 4.9 47.9 1.0 HA B:ALA218 4.9 50.5 1.0 C B:CYS199 5.0 44.9 1.0 N B:CYS222 5.0 59.5 1.0

Zinc binding site 7 out of 8 in 7z36

Zinc Binding Sites List in 7z36

Zinc binding site 7 out of 8 in the Crystal Structure of the KAP1 Tripartite Motif in Complex with the ZNF93 Krab Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Crystal Structure of the KAP1 Tripartite Motif in Complex with the ZNF93 Krab Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn503 b:91.3 occ:1.00 SG B:CYS278 2.3 91.4 1.0 ND1 B:HIS281 2.3 104.9 1.0 SG B:CYS301 2.3 86.1 1.0 SG B:CYS298 2.3 66.9 1.0 HB2 B:HIS281 3.0 118.1 1.0 CE1 B:HIS281 3.2 93.7 1.0 HB2 B:CYS278 3.2 88.2 1.0 HB2 B:CYS301 3.2 98.6 1.0 CG B:HIS281 3.2 94.8 1.0 H B:CYS301 3.2 97.8 1.0 CB B:CYS278 3.3 73.5 1.0 H B:HIS281 3.3 103.2 1.0 HE1 B:HIS281 3.3 112.4 1.0 CB B:CYS301 3.4 82.2 1.0 HB3 B:CYS278 3.4 88.2 1.0 CB B:HIS281 3.6 98.4 1.0 N B:CYS301 3.8 81.5 1.0 HB B:VAL280 3.8 109.5 1.0 H B:CYS298 3.8 84.4 1.0 CB B:CYS298 3.9 93.5 1.0 HB3 B:CYS298 3.9 112.2 1.0 HB2 B:ASP300 4.1 111.6 1.0 CA B:CYS301 4.1 82.9 1.0 N B:HIS281 4.1 86.0 1.0 HB3 B:CYS301 4.2 98.6 1.0 NE2 B:HIS281 4.3 106.2 1.0 HA B:CYS301 4.3 99.5 1.0 HB3 B:HIS281 4.3 118.1 1.0 CD2 B:HIS281 4.3 101.2 1.0 CA B:HIS281 4.5 94.7 1.0 H B:VAL280 4.5 126.6 1.0 HB2 B:CYS298 4.6 112.2 1.0 N B:CYS298 4.6 70.3 1.0 CA B:CYS278 4.7 68.9 1.0 CA B:CYS298 4.7 76.4 1.0 C B:ASP300 4.7 82.6 1.0 CB B:VAL280 4.8 91.2 1.0 O B:CYS298 4.9 65.9 1.0 CB B:ASP300 4.9 93.0 1.0 HA B:CYS278 4.9 82.7 1.0 HB2 B:GLU284 4.9 119.7 1.0 HG23 B:VAL280 4.9 111.7 1.0 H B:ASP300 5.0 94.1 1.0

Zinc binding site 8 out of 8 in 7z36

Zinc Binding Sites List in 7z36

Zinc binding site 8 out of 8 in the Crystal Structure of the KAP1 Tripartite Motif in Complex with the ZNF93 Krab Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 8 of Crystal Structure of the KAP1 Tripartite Motif in Complex with the ZNF93 Krab Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn504 b:74.3 occ:1.00 HE2 B:HIS309 1.8 123.6 1.0 ND1 B:HIS306 2.2 76.6 1.0 HD2 B:HIS309 2.2 116.5 1.0 NE2 B:HIS309 2.3 103.0 1.0 SG B:CYS293 2.3 105.7 1.0 SG B:CYS290 2.3 64.3 1.0 CD2 B:HIS309 2.5 97.1 1.0 CE1 B:HIS306 2.9 70.7 1.0 HB2 B:CYS293 2.9 84.2 1.0 HB3 B:HIS306 3.0 107.3 1.0 CG B:HIS306 3.0 90.4 1.0 HE1 B:HIS306 3.2 84.9 1.0 CB B:CYS293 3.2 70.2 1.0 CB B:HIS306 3.5 89.4 1.0 CE1 B:HIS309 3.5 93.8 1.0 H B:CYS293 3.6 91.2 1.0 CB B:CYS290 3.6 65.2 1.0 HB3 B:CYS290 3.6 78.2 1.0 HB2 B:CYS290 3.8 78.2 1.0 CG B:HIS309 3.8 92.0 1.0 HB2 B:SER292 3.8 108.9 1.0 HE22 B:GLN302 3.8 99.8 1.0 NE2 B:HIS306 3.9 74.7 1.0 HB3 B:CYS293 3.9 84.2 1.0 CD2 B:HIS306 3.9 85.2 1.0 N B:CYS293 3.9 76.0 1.0 HE1 B:HIS309 4.1 112.5 1.0 CA B:CYS293 4.2 77.4 1.0 ND1 B:HIS309 4.2 98.7 1.0 HA B:HIS306 4.2 105.0 1.0 HB2 B:HIS306 4.2 107.3 1.0 CA B:HIS306 4.5 87.5 1.0 HG21 B:THR297 4.5 57.9 1.0 HE2 B:HIS306 4.6 89.7 1.0 NE2 B:GLN302 4.6 83.2 1.0 CB B:SER292 4.6 90.7 1.0 HA B:CYS293 4.7 92.9 1.0 C B:SER292 4.7 73.1 1.0 HB3 B:SER292 4.7 108.9 1.0 HD2 B:HIS306 4.7 102.3 1.0 HB2 B:HIS309 4.8 124.4 1.0 OE1 B:GLN302 4.8 60.0 1.0 O B:HIS306 4.8 89.8 1.0 CB B:HIS309 4.9 103.7 1.0 CA B:CYS290 4.9 51.2 1.0

Reference: