Zinc in PDB 7ya1: Cryo-Em Structure of HACE2-Bound Sars-Cov-2 Omicron Spike Protein with L371S, P373S and F375S Mutations (Local Refinement)

Enzymatic activity of Cryo-Em Structure of HACE2-Bound Sars-Cov-2 Omicron Spike Protein with L371S, P373S and F375S Mutations (Local Refinement)

All present enzymatic activity of Cryo-Em Structure of HACE2-Bound Sars-Cov-2 Omicron Spike Protein with L371S, P373S and F375S Mutations (Local Refinement):
3.4.17.23;

Zinc Binding Sites:

The binding sites of Zinc atom in the Cryo-Em Structure of HACE2-Bound Sars-Cov-2 Omicron Spike Protein with L371S, P373S and F375S Mutations (Local Refinement) (pdb code 7ya1). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of HACE2-Bound Sars-Cov-2 Omicron Spike Protein with L371S, P373S and F375S Mutations (Local Refinement), PDB code: 7ya1:

Zinc binding site 1 out of 1 in 7ya1

Go back to Zinc Binding Sites List in 7ya1
Zinc binding site 1 out of 1 in the Cryo-Em Structure of HACE2-Bound Sars-Cov-2 Omicron Spike Protein with L371S, P373S and F375S Mutations (Local Refinement)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of HACE2-Bound Sars-Cov-2 Omicron Spike Protein with L371S, P373S and F375S Mutations (Local Refinement) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn706

b:53.0
occ:1.00
CE1 A:HIS374 1.6 43.3 1.0
NE2 A:HIS378 2.3 43.3 1.0
NE2 A:HIS374 2.3 43.3 1.0
OE1 A:GLU402 2.3 43.3 1.0
OE2 A:GLU402 2.4 43.3 1.0
CD A:GLU402 2.5 43.3 1.0
ND1 A:HIS374 2.7 43.3 1.0
CE1 A:HIS378 3.2 43.3 1.0
CD2 A:HIS378 3.3 43.3 1.0
CD2 A:HIS374 3.5 43.3 1.0
CG A:HIS374 3.7 43.3 1.0
CG A:GLU402 3.7 43.3 1.0
ND1 A:HIS378 4.4 43.3 1.0
CG A:HIS378 4.4 43.3 1.0
CB A:GLU402 4.5 43.3 1.0
CA A:GLU402 4.8 43.3 1.0

Reference:

Z.Zhao, J.Zhou, M.Tian, M.Huang, S.Liu, Y.Xie, P.Han, C.Bai, P.Han, A.Zheng, L.Fu, Y.Gao, Q.Peng, Y.Li, Y.Chai, Z.Zhang, X.Zhao, H.Song, J.Qi, Q.Wang, P.Wang, G.F.Gao. Omicron Sars-Cov-2 Mutations Stabilize Spike Up-Rbd Conformation and Lead to A Non-Rbm-Binding Monoclonal Antibody Escape. Nat Commun V. 13 4958 2022.
ISSN: ESSN 2041-1723
PubMed: 36002453
DOI: 10.1038/S41467-022-32665-7
Page generated: Sat Apr 8 06:22:18 2023

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