Zinc in PDB 7y9y: Structure of the CAS7-11-CSX29-Guide Rna-Target Rna (No Pfs) Complex

The binding sites of Zinc atom in the Structure of the CAS7-11-CSX29-Guide Rna-Target Rna (No Pfs) Complex (pdb code 7y9y). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Structure of the CAS7-11-CSX29-Guide Rna-Target Rna (No Pfs) Complex, PDB code: 7y9y:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Structure of the CAS7-11-CSX29-Guide Rna-Target Rna (No Pfs) Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the CAS7-11-CSX29-Guide Rna-Target Rna (No Pfs) Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1701 b:83.2 occ:1.00 SG A:CYS86 2.3 73.6 1.0 SG A:CYS126 2.3 67.2 1.0 SG A:CYS115 2.3 85.3 1.0 SG A:CYS123 2.3 72.1 1.0 CB A:CYS123 3.3 67.6 1.0 CB A:CYS115 3.4 87.4 1.0 CB A:CYS126 3.5 61.4 1.0 CB A:CYS86 3.5 71.0 1.0 N A:CYS123 3.9 70.2 1.0 N A:CYS115 4.1 87.8 1.0 N A:CYS86 4.1 66.2 1.0 CA A:CYS123 4.1 67.5 1.0 N A:CYS126 4.2 63.4 1.0 CA A:CYS115 4.3 88.7 1.0 CA A:CYS86 4.4 68.0 1.0 CA A:CYS126 4.4 60.8 1.0 O A:CYS123 4.5 66.5 1.0 NH1 A:ARG131 4.6 66.6 1.0 C A:CYS123 4.6 67.4 1.0 O A:CYS86 4.8 72.3 1.0 C A:CYS86 4.8 70.1 1.0

Zinc binding site 2 out of 4 in the Structure of the CAS7-11-CSX29-Guide Rna-Target Rna (No Pfs) Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of the CAS7-11-CSX29-Guide Rna-Target Rna (No Pfs) Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1702 b:65.0 occ:1.00 SG A:CYS477 2.3 25.9 1.0 SG A:CYS474 2.3 29.1 1.0 SG A:CYS463 2.3 47.1 1.0 SG A:CYS472 2.3 41.0 1.0 CB A:CYS472 3.1 26.8 1.0 CB A:CYS477 3.3 20.0 1.0 CB A:CYS463 3.5 28.7 1.0 CB A:CYS474 3.7 21.6 1.0 N A:CYS477 4.2 9.2 1.0 N A:CYS474 4.2 23.7 1.0 CB A:ALA465 4.3 33.1 1.0 CA A:CYS477 4.3 12.4 1.0 CA A:CYS463 4.4 27.0 1.0 CA A:CYS472 4.4 23.4 1.0 CA A:CYS474 4.5 19.8 1.0 C A:CYS472 4.5 24.3 1.0 N A:MET473 4.8 20.3 1.0 O A:CYS472 4.9 34.3 1.0 NH1 A:ARG452 4.9 10.5 1.0 C A:CYS463 5.0 34.2 1.0

Zinc binding site 3 out of 4 in the Structure of the CAS7-11-CSX29-Guide Rna-Target Rna (No Pfs) Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structure of the CAS7-11-CSX29-Guide Rna-Target Rna (No Pfs) Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1703 b:101.1 occ:1.00 SG A:CYS708 2.3 47.7 1.0 SG A:CYS706 2.3 55.2 1.0 SG A:CYS711 2.3 46.2 1.0 CB A:CYS711 3.4 27.6 1.0 CB A:CYS706 3.5 59.5 1.0 CB A:CYS708 4.0 36.9 1.0 CA A:CYS711 4.3 23.9 1.0 N A:CYS711 4.3 25.9 1.0 N A:CYS708 4.7 39.7 1.0 CA A:CYS706 4.8 59.6 1.0 CA A:CYS708 4.9 37.0 1.0

Zinc binding site 4 out of 4 in the Structure of the CAS7-11-CSX29-Guide Rna-Target Rna (No Pfs) Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Structure of the CAS7-11-CSX29-Guide Rna-Target Rna (No Pfs) Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1704 b:48.5 occ:1.00 SG A:CYS1342 2.3 14.8 1.0 SG A:CYS1312 2.3 11.6 1.0 SG A:CYS1345 2.3 10.7 1.0 SG A:CYS965 2.3 10.5 1.0 CB A:CYS965 3.2 2.6 1.0 CB A:CYS1345 3.3 0.5 1.0 CB A:CYS1342 3.4 0.0 1.0 CB A:CYS1312 3.6 12.4 1.0 N A:CYS1312 3.9 12.9 1.0 N A:CYS1342 4.0 5.8 1.0 N A:CYS965 4.2 10.0 1.0 N A:CYS1345 4.3 0.7 1.0 CA A:CYS1342 4.3 0.0 1.0 CA A:CYS965 4.3 1.6 1.0 NH1 A:ARG876 4.3 15.1 1.0 CA A:CYS1312 4.4 10.6 1.0 CA A:CYS1345 4.4 0.0 1.0 O A:CYS1342 4.9 8.0 1.0 C A:CYS1342 4.9 8.2 1.0 C A:CYS965 4.9 13.2 1.0 CG A:ARG967 4.9 9.3 1.0 C A:PRO1311 4.9 13.7 1.0 O A:CYS965 4.9 11.3 1.0

K.Kato, S.Okazaki, C.Schmitt-Ulms, K.Jiang, W.Zhou, J.Ishikawa, Y.Isayama, S.Adachi, T.Nishizawa, K.S.Makarova, E.V.Koonin, O.O.Abudayyeh, J.S.Gootenberg, H.Nishimasu. Rna-Triggered Protein Cleavage and Cell Growth Arrest By the Type III-E Crispr Nuclease-Protease. Science V. 378 882 2022.
ISSN: ESSN 1095-9203
PubMed: 36423304
DOI: 10.1126/SCIENCE.ADD7347