Zinc in PDB 7y9x: Structure of the CAS7-11-CSX29-Guide Rna Complex

The binding sites of Zinc atom in the Structure of the CAS7-11-CSX29-Guide Rna Complex (pdb code 7y9x). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Structure of the CAS7-11-CSX29-Guide Rna Complex, PDB code: 7y9x:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Structure of the CAS7-11-CSX29-Guide Rna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the CAS7-11-CSX29-Guide Rna Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1701 b:44.7 occ:1.00 SG A:CYS472 2.3 20.3 1.0 SG A:CYS474 2.3 18.8 1.0 SG A:CYS463 2.3 30.8 1.0 SG A:CYS477 2.3 22.7 1.0 CB A:CYS477 3.2 16.6 1.0 CB A:CYS472 3.2 10.0 1.0 CB A:CYS463 3.5 18.7 1.0 CB A:CYS474 3.6 11.4 1.0 N A:CYS474 4.1 13.3 1.0 N A:CYS477 4.2 15.2 1.0 CA A:CYS477 4.3 11.8 1.0 CA A:CYS474 4.4 12.3 1.0 CA A:CYS472 4.5 10.4 1.0 CB A:ALA465 4.5 17.0 1.0 C A:CYS472 4.5 13.6 1.0 CA A:CYS463 4.6 22.3 1.0 O A:CYS472 4.8 20.1 1.0 N A:MET473 4.9 12.8 1.0 C A:CYS474 4.9 16.7 1.0 O A:CYS474 5.0 13.8 1.0

Zinc binding site 2 out of 4 in the Structure of the CAS7-11-CSX29-Guide Rna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of the CAS7-11-CSX29-Guide Rna Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1702 b:53.1 occ:1.00 ND1 A:HIS703 2.1 24.4 1.0 SG A:CYS711 2.3 27.2 1.0 SG A:CYS708 2.3 26.4 1.0 SG A:CYS706 2.3 26.9 1.0 CE1 A:HIS703 2.9 22.3 1.0 CG A:HIS703 3.3 19.0 1.0 CB A:CYS708 3.3 14.5 1.0 CB A:CYS706 3.3 32.0 1.0 CB A:CYS711 3.5 15.2 1.0 N A:CYS708 3.7 24.5 1.0 CB A:HIS703 3.7 22.8 1.0 CA A:HIS703 3.8 26.1 1.0 CA A:CYS708 4.0 19.3 1.0 N A:CYS711 4.0 11.2 1.0 NE2 A:HIS703 4.1 24.1 1.0 CD2 A:HIS703 4.3 21.1 1.0 CA A:CYS711 4.4 17.4 1.0 C A:CYS706 4.4 29.1 1.0 CA A:CYS706 4.5 28.6 1.0 N A:GLU707 4.5 25.9 1.0 CD1 A:LEU701 4.5 16.3 1.0 C A:CYS708 4.6 18.0 1.0 O A:CYS708 4.7 16.9 1.0 N A:HIS703 4.7 26.4 1.0 C A:HIS703 4.8 28.5 1.0 C A:GLU707 4.8 24.6 1.0 CB A:LEU710 4.8 20.7 1.0 O A:CYS706 4.9 30.6 1.0 O A:HIS703 5.0 30.4 1.0

Zinc binding site 3 out of 4 in the Structure of the CAS7-11-CSX29-Guide Rna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structure of the CAS7-11-CSX29-Guide Rna Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1703 b:39.8 occ:1.00 SG A:CYS1342 2.3 11.8 1.0 SG A:CYS1312 2.3 0.0 1.0 SG A:CYS1345 2.3 12.6 1.0 SG A:CYS965 2.3 4.2 1.0 CB A:CYS1342 3.3 18.1 1.0 CB A:CYS1345 3.4 12.1 1.0 CB A:CYS965 3.4 16.0 1.0 CB A:CYS1312 3.4 14.7 1.0 N A:CYS1312 3.8 21.3 1.0 N A:CYS1342 3.9 13.8 1.0 N A:CYS965 4.2 17.7 1.0 N A:CYS1345 4.2 23.1 1.0 CA A:CYS1342 4.2 22.0 1.0 CA A:CYS1312 4.3 13.8 1.0 CA A:CYS965 4.3 14.4 1.0 CA A:CYS1345 4.4 21.6 1.0 CG A:ARG967 4.6 18.1 1.0 NH1 A:ARG876 4.8 22.7 1.0 C A:CYS1342 4.9 16.7 1.0 C A:PRO1311 5.0 20.2 1.0 C A:CYS965 5.0 24.1 1.0

Zinc binding site 4 out of 4 in the Structure of the CAS7-11-CSX29-Guide Rna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Structure of the CAS7-11-CSX29-Guide Rna Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1704 b:84.6 occ:1.00 SG A:CYS86 2.3 55.0 1.0 SG A:CYS123 2.3 42.8 1.0 SG A:CYS115 2.3 51.9 1.0 SG A:CYS126 2.3 45.4 1.0 CB A:CYS86 2.7 42.4 1.0 CB A:CYS115 3.3 47.3 1.0 CB A:CYS126 3.4 37.7 1.0 CB A:CYS123 3.5 42.7 1.0 N A:CYS115 3.7 43.4 1.0 N A:CYS123 3.7 43.7 1.0 CA A:CYS86 3.9 38.8 1.0 N A:CYS86 3.9 42.9 1.0 CA A:CYS115 4.0 45.5 1.0 CA A:CYS123 4.2 41.4 1.0 N A:CYS126 4.4 38.8 1.0 CA A:CYS126 4.5 36.2 1.0 C A:PRO114 4.7 42.1 1.0 NH1 A:ARG131 4.8 45.2 1.0 O A:CYS123 4.8 45.6 1.0 C A:TYR122 4.8 49.7 1.0 C A:CYS123 4.8 41.3 1.0 C A:CYS86 4.9 39.8 1.0 CD1 A:TYR122 5.0 49.1 1.0 CA A:TYR122 5.0 49.8 1.0

K.Kato, S.Okazaki, C.Schmitt-Ulms, K.Jiang, W.Zhou, J.Ishikawa, Y.Isayama, S.Adachi, T.Nishizawa, K.S.Makarova, E.V.Koonin, O.O.Abudayyeh, J.S.Gootenberg, H.Nishimasu. Rna-Triggered Protein Cleavage and Cell Growth Arrest By the Type III-E Crispr Nuclease-Protease. Science V. 378 882 2022.
ISSN: ESSN 1095-9203
PubMed: 36423304
DOI: 10.1126/SCIENCE.ADD7347