Zinc in PDB 7uo9: Sars-Cov-2 Replication-Transcription Complex Bound to Utp, in A Pre- Catalytic State

All present enzymatic activity of Sars-Cov-2 Replication-Transcription Complex Bound to Utp, in A Pre- Catalytic State:
2.7.7.48;

The structure of Sars-Cov-2 Replication-Transcription Complex Bound to Utp, in A Pre- Catalytic State also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Sars-Cov-2 Replication-Transcription Complex Bound to Utp, in A Pre- Catalytic State (pdb code 7uo9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Sars-Cov-2 Replication-Transcription Complex Bound to Utp, in A Pre- Catalytic State, PDB code: 7uo9:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Sars-Cov-2 Replication-Transcription Complex Bound to Utp, in A Pre- Catalytic State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sars-Cov-2 Replication-Transcription Complex Bound to Utp, in A Pre- Catalytic State within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:37.8 occ:1.00 ND1 A:HIS295 2.2 15.0 1.0 SG A:CYS310 2.2 14.7 1.0 SG A:CYS301 2.3 17.3 1.0 SG A:CYS306 2.3 18.0 1.0 HA A:CYS301 3.0 17.3 1.0 HB2 A:HIS295 3.0 15.0 1.0 CE1 A:HIS295 3.1 15.0 1.0 HB2 A:CYS310 3.1 14.7 1.0 CG A:HIS295 3.2 15.0 1.0 HE1 A:HIS295 3.2 15.0 1.0 CB A:CYS310 3.3 14.7 1.0 CB A:CYS301 3.3 17.3 1.0 O A:CYS306 3.3 18.0 1.0 HB3 A:CYS301 3.4 17.3 1.0 H A:HIS295 3.5 15.0 1.0 O A:HOH1192 3.6 17.3 1.0 CB A:HIS295 3.6 15.0 1.0 CA A:CYS301 3.6 17.3 1.0 HB3 A:CYS310 3.7 14.7 1.0 CB A:CYS306 3.7 18.0 1.0 C A:CYS306 3.9 18.0 1.0 HB3 A:CYS306 3.9 18.0 1.0 H A:LEU302 4.0 18.7 1.0 HD1 A:HIS309 4.0 15.4 1.0 HB2 A:CYS301 4.2 17.3 1.0 N A:HIS295 4.2 15.0 1.0 NE2 A:HIS295 4.3 15.0 1.0 HB3 A:HIS295 4.3 15.0 1.0 CA A:CYS306 4.3 18.0 1.0 H A:CYS310 4.3 14.7 1.0 CD2 A:HIS295 4.3 15.0 1.0 HA A:CYS306 4.4 18.0 1.0 HA A:ILE307 4.4 16.8 1.0 N A:CYS301 4.5 17.3 1.0 HB2 A:CYS306 4.5 18.0 1.0 CA A:HIS295 4.5 15.0 1.0 CA A:CYS310 4.6 14.7 1.0 N A:LEU302 4.7 18.7 1.0 O A:THR293 4.7 17.4 1.0 N A:ILE307 4.7 16.8 1.0 HA A:CYS298 4.7 15.8 1.0 H A:CYS301 4.7 17.3 1.0 C A:CYS301 4.7 17.3 1.0 HA A:TYR294 4.7 14.2 1.0 N A:CYS310 4.8 14.7 1.0 O A:HIS295 4.9 15.0 1.0 HG23 A:THR293 4.9 17.4 1.0 ND1 A:HIS309 4.9 15.4 1.0 HG A:LEU302 4.9 18.7 1.0

Zinc binding site 2 out of 2 in the Sars-Cov-2 Replication-Transcription Complex Bound to Utp, in A Pre- Catalytic State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Sars-Cov-2 Replication-Transcription Complex Bound to Utp, in A Pre- Catalytic State within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1002 b:40.9 occ:1.00 HG A:CYS487 1.2 21.5 1.0 ND1 A:HIS642 2.0 20.0 1.0 SG A:CYS645 2.2 24.8 1.0 SG A:CYS487 2.3 21.5 1.0 SG A:CYS646 2.3 20.5 1.0 HB3 A:HIS642 2.6 20.0 1.0 CG A:HIS642 2.9 20.0 1.0 CE1 A:HIS642 3.1 20.0 1.0 CB A:HIS642 3.2 20.0 1.0 H A:CYS487 3.2 21.5 1.0 HE1 A:HIS642 3.3 20.0 1.0 HE1 A:PHE571 3.6 18.7 1.0 CB A:CYS487 3.6 21.5 1.0 HB2 A:CYS487 3.6 21.5 1.0 HB2 A:CYS646 3.6 20.5 1.0 CB A:CYS646 3.7 20.5 1.0 N A:CYS487 3.7 21.5 1.0 CB A:CYS645 3.7 24.8 1.0 HB2 A:CYS645 3.7 24.8 1.0 HA A:HIS642 3.9 20.0 1.0 HB2 A:HIS642 3.9 20.0 1.0 HA2 A:GLY486 3.9 19.9 1.0 H A:CYS646 3.9 20.5 1.0 N A:CYS646 4.0 20.5 1.0 HZ1 A:LYS532 4.1 19.2 1.0 CE1 A:PHE571 4.1 18.7 1.0 CD2 A:HIS642 4.1 20.0 1.0 NE2 A:HIS642 4.1 20.0 1.0 CA A:HIS642 4.1 20.0 1.0 CA A:CYS487 4.2 21.5 1.0 C A:CYS645 4.2 24.8 1.0 HB3 A:CYS487 4.3 21.5 1.0 HB3 A:CYS645 4.3 24.8 1.0 HD1 A:PHE571 4.4 18.7 1.0 C A:GLY486 4.4 19.9 1.0 HB3 A:CYS646 4.4 20.5 1.0 CA A:CYS646 4.4 20.5 1.0 HE2 A:LYS532 4.4 19.2 1.0 HA A:CYS487 4.5 21.5 1.0 CA A:CYS645 4.5 24.8 1.0 CD1 A:PHE571 4.5 18.7 1.0 H A:CYS645 4.5 24.8 1.0 CA A:GLY486 4.6 19.9 1.0 O A:HIS642 4.7 20.0 1.0 HA A:CYS646 4.8 20.5 1.0 NZ A:LYS532 4.8 19.2 1.0 O A:CYS645 4.8 24.8 1.0 HZ3 A:LYS532 4.9 19.2 1.0 CZ A:PHE571 4.9 18.7 1.0 C A:HIS642 4.9 20.0 1.0 HE2 A:HIS642 4.9 20.0 1.0 HD2 A:HIS642 4.9 20.0 1.0 HA3 A:GLY486 5.0 19.9 1.0 HZ A:PHE571 5.0 18.7 1.0 HZ A:PHE528 5.0 19.9 1.0

B.F.Malone, S.A.Darst. Sars-Cov-2 Replication-Transcription Complex Bound to Utp, in A Pre-Catalytic State To Be Published.